Easy quantitative assessment of genome editing by sequence trace decomposition EK Brinkman, T Chen, M Amendola, B Van Steensel Nucleic acids research 42 (22), e168-e168, 2014 | 2331 | 2014 |
Single-cell dynamics of genome-nuclear lamina interactions J Kind, L Pagie, H Ortabozkoyun, S Boyle, SS De Vries, H Janssen, ... Cell 153 (1), 178-192, 2013 | 731 | 2013 |
The cohesin release factor WAPL restricts chromatin loop extension JHI Haarhuis, RH van der Weide, VA Blomen, JO Yáñez-Cuna, ... Cell 169 (4), 693-707. e14, 2017 | 680 | 2017 |
Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state BD Brown, B Gentner, A Cantore, S Colleoni, M Amendola, A Zingale, ... Nature biotechnology 25 (12), 1457-1467, 2007 | 679 | 2007 |
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke M Carlén, K Meletis, C Göritz, V Darsalia, E Evergren, K Tanigaki, ... Nature neuroscience 12 (3), 259-267, 2009 | 531 | 2009 |
Genome-wide maps of nuclear lamina interactions in single human cells J Kind, L Pagie, SS de Vries, L Nahidiazar, SS Dey, M Bienko, Y Zhan, ... Cell 163 (1), 134-147, 2015 | 489 | 2015 |
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters M Amendola, MA Venneri, A Biffi, E Vigna, L Naldini Nature biotechnology 23 (1), 108-116, 2005 | 387 | 2005 |
Stable knockdown of microRNA in vivo by lentiviral vectors B Gentner, G Schira, A Giustacchini, M Amendola, BD Brown, M Ponzoni, ... Nature methods 6 (1), 63-66, 2009 | 380 | 2009 |
Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3 SE Allan, AN Alstad, N Merindol, NK Crellin, M Amendola, R Bacchetta, ... Molecular Therapy 16 (1), 194-202, 2008 | 291 | 2008 |
Identification of hematopoietic stem cell–specific miRNAs enables gene therapy of globoid cell leukodystrophy B Gentner, I Visigalli, H Hiramatsu, E Lechman, S Ungari, A Giustacchini, ... Science translational medicine 2 (58), 58ra84-58ra84, 2010 | 228 | 2010 |
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus C Antoniani, V Meneghini, A Lattanzi, T Felix, O Romano, E Magrin, ... Blood, The Journal of the American Society of Hematology 131 (17), 1960-1973, 2018 | 215 | 2018 |
Optimization of CRISPR/Cas9 delivery to human hematopoietic stem and progenitor cells for therapeutic genomic rearrangements A Lattanzi, V Meneghini, G Pavani, F Amor, S Ramadier, T Felix, ... Molecular Therapy 27 (1), 137-150, 2019 | 128 | 2019 |
Nuclear lamins are not required for lamina‐associated domain organization in mouse embryonic stem cells M Amendola, B van Steensel EMBO reports 16 (5), 610-617, 2015 | 126 | 2015 |
Mechanisms and dynamics of nuclear lamina–genome interactions M Amendola, B van Steensel Current opinion in cell biology 28, 61-68, 2014 | 125 | 2014 |
Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform M Amendola, L Passerini, F Pucci, B Gentner, R Bacchetta, L Naldini Molecular therapy 17 (6), 1039-1052, 2009 | 122 | 2009 |
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype L Weber, G Frati, T Felix, G Hardouin, A Casini, C Wollenschlaeger, ... Science advances 6 (7), eaay9392, 2020 | 118 | 2020 |
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models A Lattanzi, M Neri, C Maderna, I Di Girolamo, S Martino, A Orlacchio, ... Human molecular genetics 19 (11), 2208-2227, 2010 | 86 | 2010 |
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy A Cozzi, E Rovelli, G Frizzale, A Campanella, M Amendola, P Arosio, ... Neurobiology of disease 37 (1), 77-85, 2010 | 79 | 2010 |
Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors S Bobisse, M Rondina, A Merlo, V Tisato, S Mandruzzato, M Amendola, ... Cancer research 69 (24), 9385-9394, 2009 | 77 | 2009 |
Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector E Vigna, M Amendola, F Benedicenti, AD Simmons, A Follenzi, L Naldini Molecular therapy 11 (5), 763-775, 2005 | 71 | 2005 |