Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time MR Jenkins, JA Rudd-Schmidt, JA Lopez, KM Ramsbottom, SI Mannering, ... Journal of Experimental Medicine 212 (3), 307-317, 2015 | 267 | 2015 |
Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse JA Lopez, MR Jenkins, JA Rudd-Schmidt, AJ Brennan, JC Danne, ... The Journal of Immunology 191 (5), 2328-2334, 2013 | 108 | 2013 |
Lipid order and charge protect killer T cells from accidental death JA Rudd-Schmidt, AW Hodel, T Noori, JA Lopez, HJ Cho, S Verschoor, ... Nature communications 10 (1), 5396, 2019 | 81 | 2019 |
Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin JA Spicer, G Lena, DM Lyons, KM Huttunen, CK Miller, PD O’Connor, ... Journal of medicinal chemistry 56 (23), 9542-9555, 2013 | 40 | 2013 |
Labeling phospholipid membranes with lipid mimetic luminescent metal complexes A Mechler, BD Stringer, MSH Mubin, EH Doeven, NW Phillips, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (11), 2939-2946, 2014 | 23 | 2014 |
Lipid specificity of the immune effector perforin AW Hodel, JA Rudd-Schmidt, JA Trapani, I Voskoboinik, ... Faraday Discussions 232, 236-255, 2021 | 10 | 2021 |
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1 D Castiblanco, JA Rudd-Schmidt, T Noori, VR Sutton, YH Hung, ... Blood, The Journal of the American Society of Hematology 139 (12), 1833-1849, 2022 | 9 | 2022 |
Distinguishing perforin-mediated lysis and granzyme-dependent apoptosis JA Rudd-Schmidt, JA Trapani, I Voskoboinik Methods in Enzymology 629, 291-306, 2019 | 8 | 2019 |
A cell-based functional assay that accurately links genotype to phenotype in familial HLH T Noori, JA Rudd-Schmidt, A Kane, K Frith, PE Gray, H Hu, D Hsu, ... Blood, The Journal of the American Society of Hematology 141 (19), 2330-2342, 2023 | 7 | 2023 |
ALFA-PRF: a novel approach to detect murine perforin release from CTLs into the immune synapse JA Rudd-Schmidt, RF Laine, T Noori, AJ Brennan, I Voskoboinik Frontiers in Immunology 13, 931820, 2022 | 2 | 2022 |
A cell-based functional assay that accurately links genotype to phenotype in familial HLH (vol 141, pg 2330, 2023) T Noori, JA Rudd-Schmidt, A Kane BLOOD 143 (6), 562-562, 2024 | | 2024 |
Acidic pH attenuates immune killing through inactivation of perforin AW Hodel, JA Rudd-Schmidt, T Noori, CJ Lupton, VCT Cheuk, JA Trapani, ... bioRxiv, 2024.07. 04.602105, 2024 | | 2024 |
Investigating the mechanism of cytotoxic lymphocyte resistance to perforin JA Rudd-Schmidt | | 2020 |