Programmed cell death ligand-1 (PD-L1) and CD8 expression profiling identify an immunologic subtype of pancreatic ductal adenocarcinomas with favorable survival L Danilova, WJ Ho, Q Zhu, T Vithayathil, A De Jesus-Acosta, NS Azad, ... Cancer immunology research 7 (6), 886-895, 2019 | 203 | 2019 |
Program Death 1 Immune Checkpoint and Tumor Microenvironment: Implications for Patients With Intrahepatic Cholangiocarcinoma PTM Gani F, Nagarajan N, Kim Y, Zhu Q, Luan L, Bhaijjee F, Anders RA Ann Surg Oncol 23 (8), 2610-7, 2013 | 154* | 2013 |
Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade S Berry, NA Giraldo, BF Green, TR Cottrell, JE Stein, EL Engle, H Xu, ... Science 372 (6547), eaba2609, 2021 | 147 | 2021 |
Neoadjuvant cabozantinib and nivolumab converts locally advanced HCC into resectable disease with enhanced antitumor immunity. WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ... Nature cancer 2 (9), 891-903, 2021 | 135 | 2021 |
Characterization of the immune microenvironment in hepatocellular carcinoma M Yarchoan, D Xing, L Luan, H Xu, RB Sharma, A Popovic, TM Pawlik, ... Clinical Cancer Research 23 (23), 7333-7339, 2017 | 135 | 2017 |
Axon guidance molecules promote perineural invasion and metastasis of orthotopic pancreatic tumors in mice NR Jurcak, AA Rucki, S Muth, E Thompson, R Sharma, D Ding, Q Zhu, ... Gastroenterology 157 (3), 838-850. e6, 2019 | 116 | 2019 |
Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/E2F transcription factor 1–dependent apoptotic … HX Sun, Y Xu, XR Yang, WM Wang, H Bai, RY Shi, SK Nayar, ... Hepatology 57 (3), 1088-1097, 2013 | 100 | 2013 |
The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma J Ai, Q Tang, Y Wu, Y Xu, T Feng, R Zhou, Y Chen, X Gao, Q Zhu, X Yue, ... Journal of the National Cancer Institute 103 (22), 1696-1712, 2011 | 98 | 2011 |
Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma Y Xu, V Chenna, C Hu, HX Sun, M Khan, H Bai, XR Yang, QF Zhu, YF Sun, ... Clinical Cancer Research 18 (5), 1291-1302, 2012 | 79 | 2012 |
Pharmacological activation of myosin II paralogs to correct cell mechanics defects A Surcel, WP Ng, H West-Foyle, Q Zhu, Y Ren, LB Avery, AK Krenc, ... Proceedings of the National Academy of Sciences 112 (5), 1428-1433, 2015 | 71 | 2015 |
A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human … B Hu, D Sun, C Sun, YF Sun, HX Sun, QF Zhu, XR Yang, YB Gao, ... Biochemical and biophysical research communications 468 (4), 525-532, 2015 | 68 | 2015 |
Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14 A Surcel, ES Schiffhauer, DG Thomas, Q Zhu, K DiNapoli, M Herbig, ... Biophysical Journal 116 (3), 260a, 2019 | 66 | 2019 |
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ... Nature Cancer 2 (9), 891-903, 2021 | 64 | 2021 |
Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy K Li, JA Tandurella, J Gai, Q Zhu, SJ Lim, DL Thomas, T Xia, G Mo, ... Cancer Cell 40 (11), 1374-1391. e7, 2022 | 63 | 2022 |
Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers M Yarchoan, L Cope, AN Ruggieri, RA Anders, AM Noonan, LW Goff, ... The Journal of Clinical Investigation 131 (24), 2021 | 57 | 2021 |
A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer M Yarchoan, CY Huang, Q Zhu, AK Ferguson, JN Durham, RA Anders, ... Cancer medicine 9 (4), 1485-1494, 2020 | 57 | 2020 |
Histopathological and immunophenotypic features of ipilimumab‐associated colitis compared to ulcerative colitis BL Adler, MK Pezhouh, A Kim, L Luan, Q Zhu, F Gani, M Yarchoan, ... Journal of internal medicine 283 (6), 568-577, 2018 | 51 | 2018 |
Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 KN Smith, NJ Llosa, TR Cottrell, N Siegel, H Fan, P Suri, HY Chan, H Guo, ... Journal for immunotherapy of cancer 7, 1-8, 2019 | 45 | 2019 |
Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization RAA Haibo Bai, Qingfeng Zhu, Alexandra Surcel, Tianzhi Luo, Yixin Ren, Bin ... American Journal of Physiology - Gastrointestinal and Liver Physiology 311 …, 2016 | 42 | 2016 |
Quantitative characterization of CD8+ T cell clustering and spatial heterogeneity in solid tumors C Gong, RA Anders, Q Zhu, JM Taube, B Green, W Cheng, IH Bartelink, ... Frontiers in oncology 8, 649, 2019 | 41 | 2019 |