| Accelerating biologics manufacturing by modeling or: is approval under the QbD and PAT approaches demanded by authorities acceptable without a digital-twin? S Zobel-Roos, A Schmidt, F Mestmäcker, M Mouellef, M Huter, ... Processes 7 (2), 94, 2019 | 92 | 2019 |
| Digital twin of mRNA-based SARS-COVID-19 vaccine manufacturing towards autonomous operation for improvements in speed, scale, robustness, flexibility and real-time release testing A Schmidt, H Helgers, FL Vetter, A Juckers, J Strube Processes 9 (5), 748, 2021 | 54 | 2021 |
| Digital twins in biomanufacturing S Zobel-Roos, A Schmidt, L Uhlenbrock, R Ditz, D Köster, J Strube Digital twins: Tools and concepts for smart biomanufacturing, 181-262, 2021 | 48 | 2021 |
| Towards autonomous operation by advanced process control—process analytical technology for continuous biologics antibody manufacturing H Helgers, A Schmidt, LJ Lohmann, FL Vetter, A Juckers, C Jensch, ... Processes 9 (1), 172, 2021 | 47 | 2021 |
| Process intensification in biologics manufacturing J Strube, R Ditz, M Kornecki, M Huter, A Schmidt, H Thiess, S Zobel-Roos Chemical Engineering and Processing-Process Intensification 133, 278-293, 2018 | 37 | 2018 |
| Integration of aqueous two-phase extraction as cell harvest and capture operation in the manufacturing process of monoclonal antibodies A Schmidt, M Richter, F Rudolph, J Strube Antibodies 6 (4), 21, 2017 | 33 | 2017 |
| Digital twins for continuous mRNA production H Helgers, A Hengelbrock, A Schmidt, J Strube Processes 9 (11), 1967, 2021 | 32 | 2021 |
| Distinct and quantitative validation method for predictive process modeling with examples of liquid-liquid extraction processes of complex feed mixtures A Schmidt, J Strube Processes 7 (5), 298, 2019 | 30 | 2019 |
| Accelerating biomanufacturing by modeling of continuous bioprocessing—piloting case study of monoclonal antibody manufacturing M Kornecki, A Schmidt, L Lohmann, M Huter, F Mestmäcker, L Klepzig, ... Processes 7 (8), 495, 2019 | 29 | 2019 |
| Process analytical technology as key‐enabler for digital twins in continuous biomanufacturing A Schmidt, H Helgers, LJ Lohmann, F Vetter, A Juckers, M Mouellef, ... Journal of Chemical Technology & Biotechnology 97 (9), 2336-2346, 2022 | 27 | 2022 |
| Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.—Part I: Conceptual Process Design and … M Sixt, A Schmidt, F Mestmäcker, MJ Huter, L Uhlenbrock, J Strube Processes 6 (9), 161, 2018 | 25 | 2018 |
| Technical potential for energy and GWP reduction in chemical–pharmaceutical industry in Germany and EU—focused on biologics and botanicals manufacturing A Schmidt, L Uhlenbrock, J Strube Processes 8 (7), 818, 2020 | 24 | 2020 |
| Process design and optimization towards digital twins for HIV-gag VLP production in HEK293 cells, including purification H Helgers, A Hengelbrock, A Schmidt, J Rosengarten, J Stitz, J Strube Processes 10 (2), 419, 2022 | 23 | 2022 |
| Application and fundamentals of liquid–liquid extraction processes: purification of biologicals, botanicals, and strategic metals A Schmidt, J Strube Kirk‐Othmer Encyclopedia of Chemical Technology, 1-52, 2000 | 23 | 2000 |
| Digital twin for HIV-gag VLP production in HEK293 cells A Hengelbrock, H Helgers, A Schmidt, FL Vetter, A Juckers, ... Processes 10 (5), 866, 2022 | 22 | 2022 |
| Fast and flexible mrna vaccine manufacturing as a solution to pandemic situations by adopting chemical engineering good practice—continuous autonomous operation in stainless … A Schmidt, H Helgers, FL Vetter, A Juckers, J Strube Processes 9 (11), 1874, 2021 | 22 | 2021 |
| Process automation and control strategy by quality-by-design in total continuous mRNA manufacturing platforms A Schmidt, H Helgers, FL Vetter, S Zobel-Roos, A Hengelbrock, J Strube Processes 10 (9), 1783, 2022 | 21 | 2022 |
| PAT as key-enabling technology for QbD in pharmaceutical manufacturing A conceptual review on upstream and downstream processing M Kornecki, A Schmidt, J Strube CHIMICA OGGI-CHEMISTRY TODAY 36 (6), 44-48, 2018 | 21 | 2018 |
| Development of a scale-up tool for pervaporation processes H Thiess, A Schmidt, J Strube Membranes 8 (1), 4, 2018 | 21 | 2018 |
| Integrated clarification and purification of monoclonal antibodies by membrane based separation of aqueous two-phase systems T Kruse, A Schmidt, M Kampmann, J Strube Antibodies 8 (3), 40, 2019 | 19 | 2019 |
Jörn StitzProfessor of Pharmaceutical Biotechnology, TH Köln在 th-koeln.de 的电子邮件经过验证
