Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo F Ellett, V Pazhakh, L Pase, EL Benard, H Weerasinghe, D Azabdaftari, ... PLoS pathogens 14 (6), e1007063, 2018 | 59 | 2018 |
Tools for high efficiency genetic manipulation of the human pathogen Penicillium marneffei HE Bugeja, KJ Boyce, H Weerasinghe, S Beard, A Jeziorowski, ... Fungal genetics and biology 49 (10), 772-778, 2012 | 52 | 2012 |
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways FAB Olivier, V Hilsenstein, H Weerasinghe, A Weir, S Hughes, S Crawford, ... Cell Reports 40 (12), 2022 | 29 | 2022 |
Immunometabolism in fungal infections: the need to eat to compete H Weerasinghe, A Traven Current opinion in microbiology 58, 32-40, 2020 | 28 | 2020 |
Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response H Weerasinghe, C Simm, TM Djajawi, I Tedja, TL Lo, DS Simpson, ... Cell Reports 42 (5), 2023 | 17 | 2023 |
Strategies for the molecular genetic manipulation and visualization of the human fungal pathogen Penicillium marneffei KJ Boyce, HE Bugeja, H Weerasinghe, MJ Payne, L Schreider Fungal Genetics Reports 59 (1), 1-12, 2012 | 16 | 2012 |
Disruption of iron homeostasis and mitochondrial metabolism are promising targets to inhibit Candida auris C Simm, H Weerasinghe, DR Thomas, PF Harrison, HJ Newton, ... Microbiology Spectrum 10 (2), e00100-22, 2022 | 14 | 2022 |
A unique aspartyl protease gene expansion in Talaromyces marneffei plays a role in growth inside host phagocytes M Payne, H Weerasinghe, I Tedja, A Andrianopoulos Virulence 10 (1), 277-291, 2019 | 10 | 2019 |
The novel Dbl homology/BAR domain protein, MsgA, of Talaromyces marneffei regulates yeast morphogenesis during growth inside host cells H Weerasinghe, HE Bugeja, A Andrianopoulos Scientific Reports 11 (1), 2334, 2021 | 8 | 2021 |
Organism-Wide Studies into Pathogenicity and Morphogenesis in Talaromyces Marneffei H Weerasinghe, M Payne, S Beard, A Andrianopoulos Future Microbiology 11 (4), 511-526, 2016 | 6 | 2016 |
The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress KPS Yau, H Weerasinghe, FAB Olivier, TL Lo, DR Powell, B Koch, ... PLoS Pathogens 19 (4), e1011338, 2023 | 4 | 2023 |
The short-chain fatty acid crotonate reduces invasive growth and immune escape of Candida albicans by regulating hyphal gene expression C McCrory, J Verma, TM Tucey, R Turner, H Weerasinghe, TH Beilharz, ... Mbio 14 (6), e02605-23, 2023 | 3 | 2023 |
Leveraging the MMV Pathogen Box to Engineer an Antifungal Compound with Improved Efficacy and Selectivity against Candida auris B Pan, H Weerasinghe, A Sezmis, MJ McDonald, A Traven, P Thompson, ... ACS Infectious Diseases 9 (10), 1901-1917, 2023 | 3 | 2023 |
The Escape of Candida albicans From Macrophages is Enabled by Host and Pathogen Pore-Forming Proteins FAB Olivier, V Hilsenstein, H Weerasinghe, JE Vince, MJ Hickey, ... Candida albicans, 0 | 1 | |
Metabolic homeostasis in fungal infections from the perspective of pathogens, immune cells, and whole-body systems H Weerasinghe, H Stölting, AJ Rose, A Traven Microbiology and Molecular Biology Reviews, e00171-22, 2024 | | 2024 |
The C-terminal protein interaction domain of the chromatin reader Yaf9 is critical for pathogenesis of Candida albicans TL Lo, Q Wang, J Nickson, BJW van Denderen, D Deveson Lucas, ... Msphere 9 (3), e00696-23, 2024 | | 2024 |
Candida auris evades innate immunity by using metabolic strategies to escape and kill macrophages while avoiding antimicrobial inflammation H Weerasinghe, C Simm, T Djajawi, I Tedja, TL Lo, D Shasha, N Mizrahi, ... bioRxiv, 2023.02. 28.529319, 2023 | | 2023 |
Morphological and metabolic adaptation to environmental conditions by Talaromyces marneffei and its role in the host. A Andrianopoulos, H Weerasinghe, M Payne MEDICAL MYCOLOGY 56, S63-S63, 2018 | | 2018 |
Identification and analysis of factors influencing intracellular growth of the pathogenic fungus Talaromyces marneffei H Weerasinghe University of Melbourne, 2017 | | 2017 |