| Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease EM Rocha, B De Miranda, LH Sanders Neurobiology of disease 109, 249-257, 2018 | 695 | 2018 |
| LRRK2 activation in idiopathic Parkinson’s disease R Di Maio, EK Hoffman, EM Rocha, MT Keeney, LH Sanders, ... Science translational medicine 10 (451), eaar5429, 2018 | 456 | 2018 |
| Progressive decline of glucocerebrosidase in aging and P arkinson's disease EM Rocha, GA Smith, E Park, H Cao, E Brown, P Hallett, O Isacson Annals of clinical and translational neurology 2 (4), 433-438, 2015 | 213 | 2015 |
| GSK-3α is a central regulator of age-related pathologies in mice J Zhou, TA Freeman, F Ahmad, X Shang, E Mangano, E Gao, J Farber, ... The Journal of clinical investigation 123 (4), 1821-1832, 2013 | 170 | 2013 |
| Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons EM Rocha, GA Smith, E Park, H Cao, E Brown, MA Hayes, J Beagan, ... Neurobiology of disease 82, 495-503, 2015 | 165 | 2015 |
| Sustained systemic glucocerebrosidase inhibition induces brain α-synuclein aggregation, microglia and complement C1q activation in mice EM Rocha, GA Smith, E Park, H Cao, AR Graham, E Brown, JR McLean, ... Antioxidants & redox signaling 23 (6), 550-564, 2015 | 141 | 2015 |
| Interferon-γ plays a role in paraquat-induced neurodegeneration involving oxidative and proinflammatory pathways EN Mangano, D Litteljohn, R So, E Nelson, S Peters, C Bethune, J Bobyn, ... Neurobiology of Aging 33 (7), 1411-1426, 2012 | 107 | 2012 |
| Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection JR McLean, GA Smith, EM Rocha, MA Hayes, JA Beagan, PJ Hallett, ... Neuroscience letters 576, 73-78, 2014 | 103 | 2014 |
| Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease BR De Miranda, EM Rocha, Q Bai, A El Ayadi, D Hinkle, EA Burton, ... Neurobiology of disease 115, 101-114, 2018 | 100 | 2018 |
| Proinflammatory cytokines differentially influence adult hippocampal cell proliferation depending upon the route and chronicity of administration JA Seguin, J Brennan, E Mangano, S Hayley Neuropsychiatric Disease and Treatment, 5-14, 2009 | 100 | 2009 |
| Inflammatory priming of the substantia nigra influences the impact of later paraquat exposure: neuroimmune sensitization of neurodegeneration EN Mangano, S Hayley Neurobiology of Aging 30 (9), 1361-1378, 2009 | 99 | 2009 |
| Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's … GA Smith, EM Rocha, JR McLean, MA Hayes, SC Izen, O Isacson, ... Human molecular genetics 23 (17), 4510-4527, 2014 | 96 | 2014 |
| Inflammatory Mechanisms of Neurodegeneration in Toxin‐Based Models of Parkinson′ s Disease D Litteljohn, E Mangano, M Clarke, J Bobyn, K Moloney, S Hayley Parkinson’s disease 2011 (1), 713517, 2011 | 96 | 2011 |
| Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease SE Davies, PJ Hallett, T Moens, G Smith, E Mangano, HT Kim, ... Neurobiology of disease 64, 79-87, 2014 | 90 | 2014 |
| A Nurr1 agonist causes neuroprotection in a Parkinson’s disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly (I: C) GA Smith, EM Rocha, T Rooney, P Barneoud, JR McLean, J Beagan, ... PloS one 10 (3), e0121072, 2015 | 84 | 2015 |
| LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease EM Rocha, BR De Miranda, S Castro, R Drolet, NG Hatcher, L Yao, ... Neurobiology of disease 134, 104626, 2020 | 81 | 2020 |
| LRRK2 and idiopathic Parkinson’s disease EM Rocha, MT Keeney, R Di Maio, BR De Miranda, JT Greenamyre Trends in neurosciences 45 (3), 224-236, 2022 | 80 | 2022 |
| Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain PJ Hallett, M Huebecker, OR Brekk, EB Moloney, EM Rocha, ... Neurobiology of aging 67, 189-200, 2018 | 79 | 2018 |
| Fibroblast biomarkers of sporadic Parkinson’s disease and LRRK2 kinase inhibition GA Smith, J Jansson, EM Rocha, T Osborn, PJ Hallett, O Isacson Molecular neurobiology 53, 5161-5177, 2016 | 75 | 2016 |
| Behavior and pro-inflammatory cytokine variations among submissive and dominant mice engaged in aggressive encounters: moderation by corticosterone reactivity MC Audet, EN Mangano, H Anisman Frontiers in behavioral neuroscience 4, 156, 2010 | 61 | 2010 |
