| An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity W Guo, Y Chen, X Zhou, A Kar, P Ray, X Chen, EJ Rao, M Yang, H Ye, ... Nature structural & molecular biology 18 (7), 822-830, 2011 | 339 | 2011 |
| TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response P Wang, J Deng, J Dong, J Liu, EH Bigio, M Mesulam, T Wang, L Sun, ... PLoS genetics 15 (5), e1007947, 2019 | 196 | 2019 |
| FUS interacts with HSP60 to promote mitochondrial damage J Deng, M Yang, Y Chen, X Chen, J Liu, S Sun, H Cheng, Y Li, EH Bigio, ... PLoS genetics 11 (9), e1005357, 2015 | 182 | 2015 |
| Unraveling multistate unfolding of rabbit muscle creatine kinase IM Kuznetsova, OV Stepanenko, KK Turoverov, L Zhu, JM Zhou, AL Fink, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2002 | 124 | 2002 |
| Expression of human FUS protein in Drosophila leads to progressive neurodegeneration Y Chen, M Yang, J Deng, X Chen, Y Ye, L Zhu, J Liu, H Ye, Y Shen, Y Li, ... Protein & cell 2 (6), 477-486, 2011 | 119 | 2011 |
| FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models J Deng, P Wang, X Chen, H Cheng, J Liu, K Fushimi, L Zhu, JY Wu Proceedings of the National Academy of Sciences 115 (41), E9678-E9686, 2018 | 110 | 2018 |
| Relationship between stability of folding intermediates and amyloid formation for the yeast prion Ure2p: a quantitative analysis of the effects of pH and buffer system L Zhu, XJ Zhang, LY Wang, JM Zhou, S Perrett Journal of molecular biology 328 (1), 235-254, 2003 | 104 | 2003 |
| RNA-binding proteins in neurological diseases HL Zhou, M Mangelsdorf, JH Liu, L Zhu, JY Wu Science China Life Sciences 57, 432-444, 2014 | 89 | 2014 |
| Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression R Kong, F Yi, P Wen, J Liu, X Chen, J Ren, X Li, Y Shang, Y Nie, K Wu, ... The Journal of clinical investigation 125 (12), 4407-4420, 2015 | 85 | 2015 |
| Amyloid nucleation and hierarchical assembly of Ure2p fibrils: role of asparagine/glutamine repeat and nonrepeat regions of the prion domain Y Jiang, H Li, L Zhu, JM Zhou, S Perrett Journal of Biological Chemistry 279 (5), 3361-3369, 2004 | 67 | 2004 |
| USP 33 mediates S lit‐R obo signaling in inhibiting colorectal cancer cell migration Z Huang, P Wen, R Kong, H Cheng, B Zhang, C Quan, Z Bian, M Chen, ... International journal of cancer 136 (8), 1792-1802, 2015 | 66 | 2015 |
| The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide binding L Zhu, JO Wrabl, AP Hayashi, LS Rose, PJ Thomas Molecular Biology of the Cell 19 (8), 3599-3612, 2008 | 65 | 2008 |
| An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution L Zhu, M Xu, M Yang, Y Yang, Y Li, J Deng, L Ruan, J Liu, S Du, X Liu, ... Human molecular genetics 23 (25), 6863-6877, 2014 | 64 | 2014 |
| A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding L Zhu, L Millen, JL Mendoza, PJ Thomas Journal of Biological Chemistry 285 (48), 37271-37280, 2010 | 58 | 2010 |
| Pressure denaturation of the yeast prion protein Ure2 JM Zhou, L Zhu, C Balny, S Perrett Biochemical and Biophysical Research Communications 287 (1), 147-152, 2001 | 50 | 2001 |
| Diagnostic value of salivary real‐time quaking‐induced conversion in Parkinson's disease and multiple system atrophy M Luan, Y Sun, J Chen, Y Jiang, F Li, L Wei, W Sun, J Ma, L Song, J Liu, ... Movement Disorders 37 (5), 1059-1063, 2022 | 47 | 2022 |
| PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration Y Chen, J Deng, P Wang, M Yang, X Chen, L Zhu, J Liu, B Lu, Y Shen, ... Human molecular genetics 25 (23), 5059-5068, 2016 | 44 | 2016 |
| USP33, a new player in lung cancer, mediates Slit-Robo signaling P Wen, R Kong, J Liu, L Zhu, X Chen, X Li, Y Nie, K Wu, JY Wu Protein & cell 5 (9), 704-713, 2014 | 42 | 2014 |
| TDP-43 regulates cancer-associated microRNAs X Chen, Z Fan, W McGee, M Chen, R Kong, P Wen, T Xiao, X Chen, J Liu, ... Protein & Cell 9 (10), 848-866, 2018 | 38 | 2018 |
| MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2 Y Zhang, M Chen, Z Qiu, K Hu, W McGee, X Chen, J Liu, L Zhu, JY Wu Protein & cell 7 (7), 489-500, 2016 | 36 | 2016 |
