| Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax) JD Leverson, H Zhang, J Chen, SK Tahir, DC Phillips, J Xue, P Nimmer, ... Cell death & disease 6 (1), e1590-e1590, 2015 | 507 | 2015 |
| USP7 small-molecule inhibitors interfere with ubiquitin binding L Kategaya, P Di Lello, L Rougé, R Pastor, KR Clark, J Drummond, ... Nature 550 (7677), 534-538, 2017 | 309 | 2017 |
| Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation IE Wertz, K Newton, D Seshasayee, S Kusam, C Lam, J Zhang, ... Nature 528 (7582), 370-375, 2015 | 271 | 2015 |
| Therapeutic ligands antagonize estrogen receptor function by impairing its mobility J Guan, W Zhou, M Hafner, RA Blake, C Chalouni, IP Chen, T De Bruyn, ... Cell 178 (4), 949-963. e18, 2019 | 177 | 2019 |
| New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ... Science signaling 1 (45), ra12-ra12, 2008 | 174 | 2008 |
| Long-term potentiation and contextual fear conditioning increase neuronal glutamate uptake J Levenson, E Weeber, JC Selcher, LS Kategaya, JD Sweatt, A Eskin Nature neuroscience 5 (2), 155-161, 2002 | 168 | 2002 |
| The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer JD Joseph, B Darimont, W Zhou, A Arrazate, A Young, E Ingalla, K Walter, ... Elife 5, e15828, 2016 | 137 | 2016 |
| GDC-9545 (giredestrant): a potent and orally bioavailable selective estrogen receptor antagonist and degrader with an exceptional preclinical profile for ER+ breast cancer J Liang, JR Zbieg, RA Blake, JH Chang, S Daly, AG DiPasquale, ... Journal of Medicinal Chemistry 64 (16), 11841-11856, 2021 | 111 | 2021 |
| Werner syndrome helicase is required for the survival of cancer cells with microsatellite instability L Kategaya, SK Perumal, JH Hager, LD Belmont Iscience 13, 488-497, 2019 | 86 | 2019 |
| Discovery of small-molecule inhibitors of ubiquitin specific protease 7 (USP7) using integrated NMR and in silico techniques P Di Lello, R Pastor, JM Murray, RA Blake, F Cohen, TD Crawford, ... Journal of medicinal chemistry 60 (24), 10056-10070, 2017 | 78 | 2017 |
| Long-term regulation of neuronal high-affinity glutamate and glutamine uptake in Aplysia J Levenson, S Endo, LS Kategaya, RI Fernandez, DG Brabham, J Chin, ... Proceedings of the National Academy of Sciences 97 (23), 12858-12863, 2000 | 66 | 2000 |
| Bili inhibits Wnt/β-catenin signaling by regulating the recruitment of axin to LRP6 LS Kategaya, B Changkakoty, T Biechele, WH Conrad, A Kaykas, ... PloS one 4 (7), e6129, 2009 | 37 | 2009 |
| Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock LS Kategaya, A Hilliard, L Zhang, JM Asara, LJ Ptáček, YH Fu PLoS one 7 (2), e31987, 2012 | 32 | 2012 |
| Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes C Metcalfe, E Ingalla, RA Blake, J Chang, A Daemen, T De Bruyn, ... Cancer Research 79 (4_Supplement), P5-04-07-P5-04-07, 2019 | 28 | 2019 |
| Coregulation of glutamate uptake and long-term sensitization in Aplysia O Khabour, J Levenson, LC Lyons, LS Kategaya, J Chin, JH Byrne, ... Journal of Neuroscience 24 (40), 8829-8837, 2004 | 25 | 2004 |
| Werner syndrome helicase is required for the survival of Cancer cells with microsatellite instability. iScience 13: 488–497 L Kategaya, SK Perumal, JH Hager, LD Belmont DOI: https://doi. org/10.1016/j. isci 6, 2019 | 7 | 2019 |
| Werner syndrome helicase is required for the survival of cancer cells with microsatellite instability. iScience 13, 488–497 (2019) L Kategaya, SK Perumal, JH Hager, LD Belmont Article CAS PubMed PubMed Central, 0 | 7 | |
| Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer JD Joseph, B Darimont, W Zhou, A Arrazate, A Young, E Ingalla, K Walter, ... Elife 8, e44851, 2019 | 6 | 2019 |
| Werner Syndrome Helicase Is Required for the Survival of Cancer Cells with Microsatellite Instability. iScience 2019, 13, 488–497 L Kategaya, SK Perumal, JH Hager, LD Belmont PubMed Abstract| Publisher Full Text| Free Full Text, 0 | 5 | |
| USP7 inhibitor compounds and methods of use R Blake, P Di Lello, J Drummond, CJ Heideker, L Kategaya, T Maurer, ... US Patent 9,573,899, 2017 | 1 | 2017 |
