Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression X Chen, J Deng, X Zheng, J Zhang, Z Zhou, H Wei, CG Zhan, F Zheng Chemico-biological interactions 306, 89-95, 2019 | 21 | 2019 |
Development of Fc-fused cocaine hydrolase for cocaine addiction treatment: catalytic and pharmacokinetic properties X Chen, J Deng, W Cui, S Hou, J Zhang, X Zheng, X Ding, H Wei, Z Zhou, ... The AAPS journal 20, 1-7, 2018 | 19 | 2018 |
Clinical potential of a rationally engineered enzyme for treatment of cocaine dependence: Long-lasting blocking of the psychostimulant, discriminative stimulus, and reinforcing … T Zhang, H Wei, J Deng, F Zheng, CG Zhan Neuropharmacology 176, 108251, 2020 | 15 | 2020 |
Reengineering of albumin-fused cocaine hydrolase CocH1 (TV-1380) to prolong its biological half-life Y Cai, S Zhou, Z Jin, H Wei, L Shang, J Deng, CG Zhan, F Zheng The AAPS journal 22, 1-11, 2020 | 14 | 2020 |
Effects of cebranopadol on cocaine-induced hyperactivity and cocaine pharmacokinetics in rats H Wei, L Shang, CG Zhan, F Zheng Scientific Reports 10 (1), 9254, 2020 | 11 | 2020 |
Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine L Shang, Z Jin, H Wei, S Park, CG Zhan, F Zheng Scientific Reports 13 (1), 640, 2023 | 7 | 2023 |
Cebranopadol reduces cocaine self-administration in male rats: Dose, treatment and safety consideration H Wei, T Zhang, CG Zhan, F Zheng Neuropharmacology 172, 108128, 2020 | 7 | 2020 |
In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase L Shang, H Wei, J Deng, MJ Stewart, JE LeSaint, A Kyomuhangi, S Park, ... Scientific Reports 14 (1), 10952, 2024 | | 2024 |
Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats H Wei, JE LeSaint, Z Jin, CG Zhan, F Zheng Scientific Reports 14 (1), 927, 2024 | | 2024 |