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Huimei Wei
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Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression
X Chen, J Deng, X Zheng, J Zhang, Z Zhou, H Wei, CG Zhan, F Zheng
Chemico-biological interactions 306, 89-95, 2019
212019
Development of Fc-fused cocaine hydrolase for cocaine addiction treatment: catalytic and pharmacokinetic properties
X Chen, J Deng, W Cui, S Hou, J Zhang, X Zheng, X Ding, H Wei, Z Zhou, ...
The AAPS journal 20, 1-7, 2018
192018
Clinical potential of a rationally engineered enzyme for treatment of cocaine dependence: Long-lasting blocking of the psychostimulant, discriminative stimulus, and reinforcing …
T Zhang, H Wei, J Deng, F Zheng, CG Zhan
Neuropharmacology 176, 108251, 2020
152020
Reengineering of albumin-fused cocaine hydrolase CocH1 (TV-1380) to prolong its biological half-life
Y Cai, S Zhou, Z Jin, H Wei, L Shang, J Deng, CG Zhan, F Zheng
The AAPS journal 22, 1-11, 2020
142020
Effects of cebranopadol on cocaine-induced hyperactivity and cocaine pharmacokinetics in rats
H Wei, L Shang, CG Zhan, F Zheng
Scientific Reports 10 (1), 9254, 2020
112020
Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine
L Shang, Z Jin, H Wei, S Park, CG Zhan, F Zheng
Scientific Reports 13 (1), 640, 2023
72023
Cebranopadol reduces cocaine self-administration in male rats: Dose, treatment and safety consideration
H Wei, T Zhang, CG Zhan, F Zheng
Neuropharmacology 172, 108128, 2020
72020
In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase
L Shang, H Wei, J Deng, MJ Stewart, JE LeSaint, A Kyomuhangi, S Park, ...
Scientific Reports 14 (1), 10952, 2024
2024
Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats
H Wei, JE LeSaint, Z Jin, CG Zhan, F Zheng
Scientific Reports 14 (1), 927, 2024
2024
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