The unfolded protein response triggers site-specific regulatory ubiquitylation of 40S ribosomal proteins R Higgins, JM Gendron, L Rising, R Mak, K Webb, SE Kaiser, N Zuzow, ... Molecular cell 59 (1), 35-49, 2015 | 148 | 2015 |
Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain J Sayegh, K Webb, D Cheng, MT Bedford, SG Clarke Journal of Biological Chemistry 282 (50), 36444-36453, 2007 | 146 | 2007 |
Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex D Lyumkis, D Oliveira dos Passos, EB Tahara, K Webb, EJ Bennett, ... Proceedings of the National Academy of Sciences 111 (45), 15981-15986, 2014 | 125 | 2014 |
Digestion and depletion of abundant proteins improves proteomic coverage BR Fonslow, BD Stein, KJ Webb, T Xu, J Choi, SK Park, JR Yates III Nature methods 10 (1), 54-56, 2013 | 118 | 2013 |
Identification of protein N-terminal methyltransferases in yeast and humans KJ Webb, RS Lipson, Q Al-Hadid, JP Whitelegge, SG Clarke Biochemistry 49 (25), 5225-5235, 2010 | 107 | 2010 |
A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase KJ Webb, CI Zurita-Lopez, Q Al-Hadid, A Laganowsky, BD Young, ... Journal of biological chemistry 285 (48), 37598-37606, 2010 | 91 | 2010 |
Modified MuDPIT separation identified 4488 proteins in a system-wide analysis of quiescence in yeast KJ Webb, T Xu, SK Park, JR Yates III Journal of proteome research 12 (5), 2177-2184, 2013 | 86 | 2013 |
Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements R Fu, MT Olsen, K Webb, EJ Bennett, J Lykke-Andersen Rna 22 (3), 373-382, 2016 | 81 | 2016 |
Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae RS Lipson, KJ Webb, SG Clarke Archives of biochemistry and biophysics 500 (2), 137-143, 2010 | 77 | 2010 |
A second GDP-L-galactose phosphorylase in Arabidopsis en route to vitamin C: covalent intermediate and substrate requirements for the conserved reaction CL Linster, LN Adler, K Webb, KC Christensen, C Brenner, SG Clarke Journal of Biological Chemistry 283 (27), 18483-18492, 2008 | 77 | 2008 |
Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a TB Miranda, KJ Webb, DD Edberg, R Reeves, S Clarke Biochemical and biophysical research communications 336 (3), 831-835, 2005 | 77 | 2005 |
Identification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation BD Young, DI Weiss, CI Zurita-Lopez, KJ Webb, SG Clarke, AE McBride Biochemistry 51 (25), 5091-5104, 2012 | 73 | 2012 |
Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir AC Stabell, NR Meyerson, RC Gullberg, AR Gilchrist, KJ Webb, WM Old, ... Elife 7, e31919, 2018 | 68 | 2018 |
Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab KJ Webb, A Laganowsky, JP Whitelegge, SG Clarke Journal of biological chemistry 283 (51), 35561-35568, 2008 | 64 | 2008 |
An isothermal shift assay for proteome scale drug-target identification KA Ball, KJ Webb, SJ Coleman, KA Cozzolino, J Jacobsen, KR Jones, ... Communications biology 3 (1), 1-10, 2020 | 60 | 2020 |
Decoys untangle complicated redundancy and reveal targets of circadian clock F-box proteins CM Lee, A Feke, MW Li, C Adamchek, K Webb, J Pruneda-Paz, ... Plant physiology 177 (3), 1170-1186, 2018 | 59 | 2018 |
A mass spectrometric study on the in vitro methylation of HMGA1a and HMGA1b proteins by PRMTs: methylation specificity, the effect of binding to AT-rich duplex DNA, and the … Y Zou, K Webb, AD Perna, Q Zhang, S Clarke, Y Wang Biochemistry 46 (26), 7896-7906, 2007 | 49 | 2007 |
Facile synthesis of a fluorescent deoxycytidine analogue suitable for probing the RecA nucleoprotein filament SF Singleton, F Shan, MW Kanan, CM McIntosh, CJ Stearman, JS Helm, ... Organic letters 3 (24), 3919-3922, 2001 | 49 | 2001 |
Synergistic activation of the insulin receptor via two distinct sites J Li, J Park, JP Mayer, KJ Webb, E Uchikawa, J Wu, S Liu, X Zhang, ... Nature structural & molecular biology 29 (4), 357-368, 2022 | 41 | 2022 |
Using the ubiquitin-modified proteome to monitor distinct and spatially restricted protein homeostasis dysfunction JM Gendron, K Webb, B Yang, L Rising, N Zuzow, EJ Bennett Molecular & cellular proteomics 15 (8), 2576-2593, 2016 | 39 | 2016 |