Andromeda: a peptide search engine integrated into the MaxQuant environment J Cox, N Neuhauser, A Michalski, RA Scheltema, JV Olsen, M Mann Journal of proteome research 10 (4), 1794-1805, 2011 | 5602 | 2011 |
The Q Exactive HF, a Benchtop mass spectrometer with a pre-filter, high-performance quadrupole and an ultra-high-field Orbitrap analyzer RA Scheltema, JP Hauschild, O Lange, D Hornburg, E Denisov, E Damoc, ... Molecular & Cellular Proteomics 13 (12), 3698-3708, 2014 | 402 | 2014 |
PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis RA Scheltema, A Jankevics, RC Jansen, MA Swertz, R Breitling Analytical chemistry 83 (7), 2786-2793, 2011 | 357 | 2011 |
System-wide molecular evidence for phenotypic buffering in Arabidopsis J Fu, JJB Keurentjes, H Bouwmeester, T America, FWA Verstappen, ... Nature genetics 41 (2), 166-167, 2009 | 294 | 2009 |
Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification F Liu, P Lössl, R Scheltema, R Viner, AJR Heck Nature communications 8 (1), 15473, 2017 | 266 | 2017 |
Time‐and compartment‐resolved proteome profiling of the extracellular niche in lung injury and repair HB Schiller, IE Fernandez, G Burgstaller, C Schaab, RA Scheltema, ... Molecular systems biology 11 (7), 819, 2015 | 241 | 2015 |
Direct proteomic quantification of the secretome of activated immune cells F Meissner, RA Scheltema, HJ Mollenkopf, M Mann Science 340 (6131), 475-478, 2013 | 218 | 2013 |
Efficient and robust proteome-wide approaches for cross-linking mass spectrometry O Klykov, B Steigenberger, S Pektaş, D Fasci, AJR Heck, RA Scheltema Nature protocols 13 (12), 2964-2990, 2018 | 155 | 2018 |
Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4 C Benda, J Ebert, RA Scheltema, HB Schiller, M Baumgärtner, F Bonneau, ... Molecular cell 56 (1), 43-54, 2014 | 145 | 2014 |
LifeTime and improving European healthcare through cell-based interceptive medicine N Rajewsky, G Almouzni, SA Gorski, S Aerts, I Amit, MG Bertero, C Bock, ... Nature, 1-14, 2020 | 139 | 2020 |
Towards a structurally resolved human protein interaction network DF Burke, P Bryant, I Barrio-Hernandez, D Memon, G Pozzati, A Shenoy, ... Nature Structural & Molecular Biology 30 (2), 216-225, 2023 | 135 | 2023 |
Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules A Kamleh, MP Barrett, D Wildridge, RJS Burchmore, RA Scheltema, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2008 | 132 | 2008 |
First community-wide, comparative cross-linking mass spectrometry study C Iacobucci, C Piotrowski, R Aebersold, BC Amaral, P Andrews, K Bernfur, ... Analytical chemistry 91 (11), 6953-6961, 2019 | 130 | 2019 |
Histone interaction landscapes visualized by crosslinking mass spectrometry in intact cell nuclei D Fasci, H van Ingen, RA Scheltema, AJR Heck Molecular & Cellular Proteomics 17 (10), 2018 | 119 | 2018 |
Metabolomics to unveil and understand phenotypic diversity between pathogen populations R t'Kindt, RA Scheltema, A Jankevics, K Brunker, S Rijal, JC Dujardin, ... PLoS neglected tropical diseases 4 (11), e904, 2010 | 117 | 2010 |
Probabilistic assignment of formulas to mass peaks in metabolomics experiments S Rogers, RA Scheltema, M Girolami, R Breitling Bioinformatics 25 (4), 512-518, 2009 | 117 | 2009 |
Spacer capture and integration by a type IF Cas1–Cas2-3 CRISPR adaptation complex RD Fagerlund, ME Wilkinson, O Klykov, A Barendregt, FG Pearce, ... Proceedings of the National Academy of Sciences 114 (26), E5122-E5128, 2017 | 116 | 2017 |
PhoX: an IMAC-enrichable cross-linking reagent B Steigenberger, RJ Pieters, AJR Heck, RA Scheltema ACS central science 5 (9), 1514-1522, 2019 | 112 | 2019 |
Metabolomic Characterization of the Salt Stress Response in Streptomyces coelicolor S Kol, ME Merlo, RA Scheltema, M De Vries, RJ Vonk, NA Kikkert, ... Applied and environmental microbiology 76 (8), 2574-2581, 2010 | 95 | 2010 |
Implementation of ultraviolet photodissociation on a benchtop Q exactive mass spectrometer and its application to phosphoproteomics KL Fort, A Dyachenko, CM Potel, E Corradini, F Marino, A Barendregt, ... Analytical chemistry 88 (4), 2303-2310, 2016 | 91 | 2016 |