| Structure and mechanism of a cyclic trinucleotide-activated bacterial endonuclease mediating bacteriophage immunity RK Lau, Q Ye, EA Birkholz, KR Berg, L Patel, IT Mathews, JD Watrous, ... Molecular cell 77 (4), 723-733. e6, 2020 | 170 | 2020 |
| CBASS immunity uses CARF-related effectors to sense 3′–5′-and 2′–5′-linked cyclic oligonucleotide signals and protect bacteria from phage infection B Lowey, AT Whiteley, AFA Keszei, BR Morehouse, IT Mathews, ... Cell 182 (1), 38-49. e17, 2020 | 163 | 2020 |
| HORMA domain proteins and a Trip13-like ATPase regulate bacterial cGAS-like enzymes to mediate bacteriophage immunity Q Ye, RK Lau, IT Mathews, EA Birkholz, JD Watrous, CS Azimi, J Pogliano, ... Molecular cell 77 (4), 709-722. e7, 2020 | 132 | 2020 |
| Implications of Rho GTPase signaling in glioma cell invasion and tumor progression SP Fortin Ensign, IT Mathews, MH Symons, ME Berens, NL Tran Frontiers in oncology 3, 241, 2013 | 130 | 2013 |
| Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease X Chu, M Jaeger, J Beumer, OB Bakker, R Aguirre-Gamboa, M Oosting, ... Genome biology 22, 1-22, 2021 | 43 | 2021 |
| Mcl-1 mediates TWEAK/Fn14-induced non–small cell lung cancer survival and therapeutic response TG Whitsett, IT Mathews, MH Cardone, RJ Lena, WE Pierceall, M Bittner, ... Molecular Cancer Research 12 (4), 550-559, 2014 | 43 | 2014 |
| Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response R Dhanwani, M Takahashi, IT Mathews, C Lenzi, A Romanov, JD Watrous, ... Science Advances 6 (30), eaba3688, 2020 | 37 | 2020 |
| Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells A Roos, HD Dhruv, IT Mathews, LJ Inge, S Tuncali, LK Hartman, D Chow, ... Oncotarget 8 (7), 12234, 2017 | 35 | 2017 |
| Metabolic programs of T cell tissue residency empower tumour immunity M Reina-Campos, M Heeg, K Kennewick, IT Mathews, G Galletti, V Luna, ... Nature 621 (7977), 179-187, 2023 | 33 | 2023 |
| The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis … SPF Ensign, IT Mathews, JM Eschbacher, JC Loftus, MH Symons, ... Journal of Biological Chemistry 288 (30), 21887-21897, 2013 | 32 | 2013 |
| SGEF is regulated via TWEAK/Fn14/NF-κB signaling and promotes survival by modulation of the DNA repair response to temozolomide SPF Ensign, A Roos, IT Mathews, HD Dhruv, S Tuncali, JN Sarkaria, ... Molecular Cancer Research 14 (3), 302-312, 2016 | 19 | 2016 |
| Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway HD Dhruv, A Roos, PJ Tomboc, S Tuncali, A Chavez, I Mathews, ... Journal of neuro-oncology 126, 397-404, 2016 | 15 | 2016 |
| Nontargeted mass spectrometry of dried blood spots for interrogation of the human circulating metabolome C Ward, S Nallamshetty, JD Watrous, E Acres, T Long, IT Mathews, ... Journal of Mass Spectrometry 56 (8), e4772, 2021 | 11 | 2021 |
| ReIGNITE radiation therapy boost: a prospective, international study of radiation oncologists’ accuracy in contouring prostate tumors for focal radiation therapy boost on … AJ Lui, K Kallis, AY Zhong, TS Hussain, C Conlin, LA Digma, N Phan, ... International Journal of Radiation Oncology* Biology* Physics 117 (5), 1145-1152, 2023 | 10 | 2023 |
| Functional analysis of immune signature genes in Th1* memory cells links ISOC1 and pyrimidine metabolism to IFN-γ and IL-17 production Y Kushnareva, IT Mathews, AY Andreyev, G Altay, ... The Journal of Immunology 206 (6), 1181-1193, 2021 | 8 | 2021 |
| Implications of Rho GTPase signaling in glioma cell invasion and tumor progression. Front Oncol. 2013; 3: 241 SP Fortin Ensign, IT Mathews, MH Symons, ME Berens, NL Tran | 5 | 2013 |
| HORMA domain proteins and a Pch2-like ATPase regulate bacterial cGAS-like enzymes to mediate bacteriophage immunity Q Ye, RK Lau, IT Mathews, JD Watrous, CS Azimi, M Jain, KD Corbett bioRxiv, 694695, 2019 | 4 | 2019 |
| ReIGNITE RT boost: an international study testing the accuracy and feasibility of using restriction spectrum imaging (RSI) MRI to guide intraprostatic tumor target volume for … AJ Lui, K Kallis, AY Zhong, TS Hussain, C Conlin, LA Digma, N Phan, ... medRxiv, 2022.12. 13.22283420, 2022 | 3 | 2022 |
| Restriction Spectrum Imaging as a quantitative biomarker for prostate cancer with reliable positive predictive value M Rojo Domingo, DD Do, CC Conlin, A Bagrodia, T Barrett, MT Baxter, ... medRxiv, 2024.06. 05.24308468, 2024 | 1 | 2024 |
| Linoleoyl-lysophosphatidylcholine suppresses immune-related adverse events due to immune checkpoint blockade IT Mathews, P Saminathan, M Henglin, M Liu, N Nadig, C Fang, ... medRxiv, 2024 | | 2024 |
