Molecular structure of the human CFTR ion channel F Liu, Z Zhang, L Csanády, DC Gadsby, J Chen Cell 169 (1), 85-95. e8, 2017 | 551 | 2017 |
Conformational changes of CFTR upon phosphorylation and ATP binding Z Zhang, F Liu, J Chen Cell 170 (3), 483-491. e8, 2017 | 246 | 2017 |
Molecular structure of the ATP-bound, phosphorylated human CFTR Z Zhang, F Liu, J Chen Proceedings of the National Academy of Sciences 115 (50), 12757-12762, 2018 | 222 | 2018 |
Structural identification of a hotspot on CFTR for potentiation F Liu, Z Zhang, A Levit, J Levring, KK Touhara, BK Shoichet, J Chen Science 364 (6446), 1184-1188, 2019 | 218 | 2019 |
Molecular structures of the eukaryotic retinal importer ABCA4 F Liu, J Lee, J Chen Elife 10, e63524, 2021 | 45 | 2021 |
Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition A Gorelik, F Liu, K Illes, B Nagar Journal of Biological Chemistry 292 (17), 7087-7094, 2017 | 36 | 2017 |
Structure-based discovery of CFTR potentiators and inhibitors F Liu, AL Kaplan, J Levring, J Einsiedel, S Tiedt, K Distler, NS Omattage, ... Cell, 2024 | 1 | 2024 |
Small vs. large library docking for positive allosteric modulators of the calcium sensing receptor F Liu, CG Wu, CL Tu, I Glenn, J Meyerowitz, AL Kaplan, J Lyu, Z Cheng, ... bioRxiv, 2024 | 1 | 2024 |
Structure-based discovery of cannabinoid-1 receptor agonists with reduced side effects TA Tummino, C Iliopoulos-Tsoutsouvas, JM Braz, ES O’Brien, RM Stein, ... bioRxiv, 2023.02. 27.530254, 2023 | 1 | 2023 |
The impact of Library Size and Scale of Testing on Virtual Screening F Liu, O Mailhot, IS Glenn, SF Vigneron, V Bassim, X Xu, ... bioRxiv, 2024.07. 08.602536, 2024 | | 2024 |
Identifying Artifacts from Large Library Docking Y Wu, F Liu, I Glenn, K Fonseca-Valencia, L Paris, Y Xiong, SV Jerome, ... bioRxiv, 2024.07. 17.603966, 2024 | | 2024 |
Structure-based discovery of positive allosteric modulators for the calcium sensing receptor. F Liu, CG Wu, CL Tu, I Glenn, J Meyerowitz, AL Kaplan, J Lyu, Z Cheng, ... Biorxiv: the Preprint Server for Biology, 2023 | | 2023 |
Filtering Artifacts from Top Ranked Docked Molecules with an Implicit Solvent Model Y Wu, F Liu, FV Karla, LB Charles III, B Shoichet PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Large library docking for cannabinoid-1 receptor agonists with reduced side effects TA Tummino, C Iliopoulos-Tsoutsouvas, JM Braz, ES O'Brien, RM Stein, ... bioRxiv, 2023 | | 2023 |