Environment drives selection and function of enhancers controlling tissue-specific macrophage identities D Gosselin, VM Link, CE Romanoski, GJ Fonseca, DZ Eichenfield, ... Cell 159 (6), 1327-1340, 2014 | 1309 | 2014 |
An environment-dependent transcriptional network specifies human microglia identity D Gosselin, D Skola, NG Coufal, IR Holtman, JCM Schlachetzki, E Sajti, ... Science 356 (6344), eaal3222, 2017 | 1027 | 2017 |
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription MTY Lam, H Cho, HP Lesch, D Gosselin, S Heinz, Y Tanaka-Oishi, ... Nature 498 (7455), 511-515, 2013 | 581 | 2013 |
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association A Nott, IR Holtman, NG Coufal, JCM Schlachetzki, M Yu, R Hu, CZ Han, ... Science 366 (6469), 1134-1139, 2019 | 538 | 2019 |
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors A Crotti, C Benner, BE Kerman, D Gosselin, C Lagier-Tourenne, ... Nature neuroscience 17 (4), 513-521, 2014 | 320 | 2014 |
Niche-specific reprogramming of epigenetic landscapes drives myeloid cell diversity in nonalcoholic steatohepatitis JS Seidman, TD Troutman, M Sakai, A Gola, NJ Spann, H Bennett, ... Immunity 52 (6), 1057-1074. e7, 2020 | 303 | 2020 |
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons ST Schafer, ACM Paquola, S Stern, D Gosselin, M Ku, M Pena, TJM Kuret, ... Nature neuroscience 22 (2), 243-255, 2019 | 236 | 2019 |
TLR9 contributes to the recognition of EBV by primary monocytes and plasmacytoid dendritic cells S Fiola, D Gosselin, K Takada, J Gosselin The Journal of Immunology 185 (6), 3620-3631, 2010 | 204 | 2010 |
Role of IL-1 and TNF in the brain: twenty years of progress on a Dr. Jekyll/Mr. Hyde duality of the innate immune system D Gosselin, S Rivest Brain, behavior, and immunity 21 (3), 281-289, 2007 | 182 | 2007 |
Phospholipase A2 regulates eicosanoid class switching during inflammasome activation PC Norris, D Gosselin, D Reichart, CK Glass, EA Dennis Proceedings of the National Academy of Sciences 111 (35), 12746-12751, 2014 | 133 | 2014 |
MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation D Gosselin, S Rivest Molecular psychiatry 13 (5), 480-497, 2008 | 112 | 2008 |
Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice Y Sergerie, G Boivin, D Gosselin, S Rivest The Journal of infectious diseases 195 (6), 817-825, 2007 | 94 | 2007 |
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells KA Allison, E Sajti, JG Collier, D Gosselin, TD Troutman, EL Stone, ... Elife 5, e10134, 2016 | 80 | 2016 |
Cx3cr1-deficient microglia exhibit a premature aging transcriptome S Gyoneva, R Hosur, D Gosselin, B Zhang, Z Ouyang, AC Cotleur, ... Life science alliance 2 (6), 2019 | 76 | 2019 |
Epigenomics of macrophages D Gosselin, CK Glass Immunological reviews 262 (1), 96-112, 2014 | 72 | 2014 |
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages DZ Eichenfield, TD Troutman, VM Link, MT Lam, H Cho, D Gosselin, ... elife 5, e13024, 2016 | 71 | 2016 |
A monocyte gene expression signature in the early clinical course of Parkinson’s disease JCM Schlachetzki, I Prots, J Tao, HB Chun, K Saijo, D Gosselin, B Winner, ... Scientific Reports 8 (1), 10757, 2018 | 46 | 2018 |
Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity MA Bellavance, D Gosselin, VW Yong, PK Stys, S Rivest Brain Structure and Function 220, 1759-1776, 2015 | 46 | 2015 |
Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis N Boivin, R Menasria, D Gosselin, S Rivest, G Boivin Journal of general virology 93 (6), 1294-1304, 2012 | 43 | 2012 |
Estrogen receptor transrepresses brain inflammation D Gosselin, S Rivest Cell 145 (4), 495-497, 2011 | 31 | 2011 |