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Daniel S Chen
Daniel S Chen
Engenuity Life Sciences
在 engenuitylife.com 的电子邮件经过验证 - 首页
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引用次数
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Oncology meets immunology: the cancer-immunity cycle
DS Chen, I Mellman
immunity 39 (1), 1-10, 2013
64712013
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
RS Herbst, JC Soria, M Kowanetz, GD Fine, O Hamid, MS Gordon, ...
Nature 515 (7528), 563-567, 2014
54132014
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
A Rittmeyer, F Barlesi, D Waterkamp, K Park, F Ciardiello, J Von Pawel, ...
The Lancet 389 (10066), 255-265, 2017
47072017
Elements of cancer immunity and the cancer–immune set point
DS Chen, I Mellman
Nature 541 (7637), 321-330, 2017
43332017
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ...
Nature 554 (7693), 544-548, 2018
38662018
Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial
L Fehrenbacher, A Spira, M Ballinger, M Kowanetz, J Vansteenkiste, ...
The Lancet 387 (10030), 1837-1846, 2016
28872016
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
T Powles, JP Eder, GD Fine, FS Braiteh, Y Loriot, C Cruz, J Bellmunt, ...
Nature 515 (7528), 558-562, 2014
26082014
VEGF in signaling and disease: beyond discovery and development
RS Apte, DS Chen, N Ferrara
Cell 176 (6), 1248-1264, 2019
19252019
Top 10 challenges in cancer immunotherapy
PS Hegde, DS Chen
Immunity 52 (1), 17-35, 2020
14762020
Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma
DF McDermott, MA Huseni, MB Atkins, RJ Motzer, BI Rini, B Escudier, ...
Nature medicine 24 (6), 749-757, 2018
10482018
Molecular pathways: next-generation immunotherapy—inhibiting programmed death-ligand 1 and programmed death-1
DS Chen, BA Irving, FS Hodi
Clinical cancer research 18 (24), 6580-6587, 2012
7252012
Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
JJ Wallin, JC Bendell, R Funke, M Sznol, K Korski, S Jones, G Hernandez, ...
Nature communications 7 (1), 1-8, 2016
6432016
Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)
JM Kim, DS Chen
Annals of Oncology 27 (8), 1492-1504, 2016
6042016
T cells use two directionally distinct pathways for cytokine secretion
M Huse, BF Lillemeier, MS Kuhns, DS Chen, MM Davis
Nature immunology 7 (3), 247-255, 2006
5012006
An optimized optogenetic clustering tool for probing protein interaction and function
A Taslimi, JD Vrana, D Chen, S Borinskaya, BJ Mayer, MJ Kennedy, ...
Nature communications 5 (1), 4925, 2014
3782014
Molecular biomarker analyses using circulating tumor cells
EA Punnoose, SK Atwal, JM Spoerke, H Savage, A Pandita, RF Yeh, ...
PloS one 5 (9), e12517, 2010
3632010
Immune-modified response evaluation criteria in solid tumors (imRECIST): refining guidelines to assess the clinical benefit of cancer immunotherapy
FS Hodi, M Ballinger, B Lyons, JC Soria, M Nishino, J Tabernero, ...
Journal of Clinical Oncology 36 (9), 850-858, 2018
3212018
Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy
M Mayoux, A Roller, V Pulko, S Sammicheli, S Chen, E Sum, C Jost, ...
Science translational medicine 12 (534), eaav7431, 2020
3052020
A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors.
RS Herbst, MS Gordon, GD Fine, JA Sosman, JC Soria, O Hamid, ...
Journal of Clinical Oncology 31 (15_suppl), 3000-3000, 2013
2882013
A systemic complete response of metastatic melanoma to local radiation and immunotherapy
SM Hiniker, DS Chen, S Reddy, DT Chang, JC Jones, JA Mollick, ...
Translational oncology 5 (6), 404-407, 2012
2592012
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