Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion H Nakahara, L Howard, EW Thompson, H Sato, M Seiki, Y Yeh, WT Chen Proceedings of the National Academy of Sciences 94 (15), 7959-7964, 1997 | 532 | 1997 |
Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype B Neuhuber, G Gallo, L Howard, L Kostura, A Mackay, I Fischer Journal of neuroscience research 77 (2), 192-204, 2004 | 506 | 2004 |
A novel protease-docking function of integrin at invadopodia SC Mueller, G Ghersi, SK Akiyama, QXA Sang, L Howard, ... Journal of Biological Chemistry 274 (35), 24947-24952, 1999 | 325 | 1999 |
Effects of plating density and culture time on bone marrow stromal cell characteristics B Neuhuber, SA Swanger, L Howard, A Mackay, I Fischer Experimental hematology 36 (9), 1176-1185, 2008 | 314 | 2008 |
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1 L Howard, KK Nelson, RA Maciewicz, CP Blobel Journal of Biological Chemistry 274 (44), 31693-31699, 1999 | 241 | 1999 |
Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors JM McMahon, S Conroy, M Lyons, U Greiser, C O'shea, P Strappe, ... Stem cells and development 15 (1), 87-96, 2006 | 239 | 2006 |
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease ML Pineiro-Sanchez, LA Goldstein, J Dodt, L Howard, Y Yeh, WT Chen Journal of Biological Chemistry 272 (12), 7595-7601, 1997 | 222 | 1997 |
Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28 L HOWARD, RA MACIEWICZ, CP BLOBEL Biochemical Journal 348 (1), 21-27, 2000 | 207 | 2000 |
Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types L Howard, X Lu, S Mitchell, S Griffiths, P Glynn Biochemical Journal 317 (1), 45-50, 1996 | 161 | 1996 |
Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model A Mohr, M Lyons, L Deedigan, T Harte, G Shaw, L Howard, F Barry, ... Journal of cellular and molecular medicine 12 (6b), 2628-2643, 2008 | 140 | 2008 |
Long QT syndrome: genetics and future perspective E Wallace, L Howard, M Liu, T O’Brien, D Ward, S Shen, T Prendiville Pediatric cardiology 40, 1419-1430, 2019 | 136 | 2019 |
Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis F Sharif, SO Hynes, R Cooney, L Howard, J McMahon, K Daly, J Crowley, ... Molecular therapy 16 (10), 1674-1680, 2008 | 115 | 2008 |
Growth differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy CM Coleman, EE Vaughan, DC Browe, E Mooney, L Howard, F Barry Stem cells and development 22 (13), 1968-1976, 2013 | 110 | 2013 |
Potential of rat bone marrow-derived mesenchymal stem cells as vehicles for delivery of neurotrophins to the Parkinsonian rat brain TC Moloney, GE Rooney, FP Barry, L Howard, E Dowd Brain research 1359, 33-43, 2010 | 97 | 2010 |
Catalytic activity of ADAM28 L Howard, Y Zheng, M Horrocks, RA Maciewicz, C Blobel FEBS letters 498 (1), 82-86, 2001 | 97 | 2001 |
The reduction in immunogenicity of neurotrophin overexpressing stem cells after intra-striatal transplantation by encapsulation in an in situ gelling collagen hydrogel DB Hoban, B Newland, TC Moloney, L Howard, A Pandit, E Dowd Biomaterials 34 (37), 9420-9429, 2013 | 95 | 2013 |
Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury R Cooney, SO Hynes, F Sharif, L Howard, T O'Brien Gene therapy 14 (5), 396-404, 2007 | 94 | 2007 |
GDNF-secreting mesenchymal stem cells provide localized neuroprotection in an inflammation-driven rat model of Parkinson’s disease DB Hoban, L Howard, E Dowd Neuroscience 303, 402-411, 2015 | 92 | 2015 |
A medium detecting β‐glucuronidase for the simultaneous membrane filtration enumeration of Escherichia coli and coliforms from drinking water DP Sartory, L Howard Letters in Applied Microbiology 15 (6), 273-276, 1992 | 79 | 1992 |
Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate GE Rooney, C Moran, SS McMahon, T Ritter, M Maenz, A Flügel, ... Tissue Engineering Part A 14 (5), 681-690, 2008 | 75 | 2008 |