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King Pan NG
King Pan NG
Junior Principal Investigator/KKH
在 kkh.com.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6732012
Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins
KP Ng, G Potikyan, ROV Savene, CT Denny, VN Uversky, KAW Lee
Proceedings of the National Academy of Sciences 104 (2), 479-484, 2007
1142007
Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition
KP Ng, A Manjeri, KL Lee, W Huang, SY Tan, CTH Chuah, L Poellinger, ...
Blood, The Journal of the American Society of Hematology 123 (21), 3316-3326, 2014
1022014
The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors
TK Ko, CTH Chuah, JWJ Huang, KP Ng, ST Ong
Oncotarget 5 (19), 9033, 2014
702014
An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia
TK Ko, A Javed, KL Lee, TN Pathiraja, X Liu, S Malik, SX Soh, XT Heng, ...
Blood, The Journal of the American Society of Hematology 135 (26), 2337-2353, 2020
592020
Rapid production of clinical‐grade SARS‐CoV‐2 specific T cells
W Leung, TG Soh, YC Linn, JGH Low, J Loh, M Chan, WJ Chng, LP Koh, ...
Advances in cell and gene therapy 3 (4), e101, 2020
282020
The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia
TK Ko, H San Chin, CTH Chuah, JWJ Huang, KP Ng, SL Khaw, ...
Oncotarget 7 (3), 2721, 2016
232016
The arginase inhibitor Nω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 …
KP Ng, A Manjeri, LM Lee, ZE Chan, CY Tan, QD Tan, AQ Majeed, ...
PLoS One 13 (10), e0205254, 2018
142018
The RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell lines
Y Zhao, KKC Li, KP Ng, CH Ng, KAW Lee
Protein & cell 3 (11), 846-854, 2012
142012
RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct
BL Chau, KP Ng, KKC Li, KAW Lee
Transcription 7 (4), 141-151, 2016
92016
In vitro activity of the EWS oncogene transcriptional activation domain
KP Ng, KKC Li, KAW Lee
Biochemistry 48 (13), 2849-2857, 2009
82009
Human bone xenografts: from preclinical testing for regenerative medicine to modeling of diseases
MSK Chong, C Bao, KP Ng, J Lim, JKY Chan
Current Molecular Biology Reports 2, 158-170, 2016
72016
A transcription assay for EWS oncoproteins in Xenopus oocytes
KP Ng, F Cheung, KAW Lee
Protein & cell 1 (10), 927-934, 2010
42010
SUCCESSFUL MANUFACTURING OF CLINICAL-GRADE SARS-CoV-2 SPECIFIC T CELLS FOR ADOPTIVE CELL THERAPY
W Leung, TG Soh, YC Linn, JGH Low, J Loh, M Chan, WJ Chng, LP Koh, ...
medRxiv, 2020.04. 24.20077487, 2020
32020
The genomic and epigenomic landscapes of blast crisis transformation in chronic myeloid leukemia
ST Ong, T Pathiraja, A Javed, XXS Soh, S Malik, JHJ Tan, TK Ko, ...
Blood, The Journal of the American Society of Hematology 126 (23), 3737-3737, 2015
32015
The BIM deletion polymorphism: a paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia
TK Ko, C Chuah, JWJ Huang, KP Ng, ST Ong
Blood 122 (21), 3977, 2013
22013
Physiologic Hypoxia Protects Chronic Myelogenous Leukemia Progenitors From Elimination by Imatinib Mesylate.
KP Ng, TY Poh, WT Sun, C Chuah, ST Ong
Blood 114 (22), 2181, 2009
22009
Method of detecting resistance to cancer therapy
Y Ruan, ST Ong, KP Ng, CTH Chuah, AM Hillmer, WC Juan
US Patent App. 13/993,745, 2013
12013
The BCL-2 Inhibitor ABT-199 Enhances Imatinib-Induced Cell Death In Chronic Phase CML Progenitors
TK Ko, C Chuah, J Huang, KP Ng, ST Ong
Blood 122 (21), 3978, 2013
12013
A Common Deletion Polymorphism in the BIM Gene Contributes to Intrinsic Imatinib Resistance in Chronic Myelogenous Leukemia
AM Hillmer, KP Ng, C Chuah, WC Juan, TK Ko, ASM Teo, PN Ariyaratne, ...
Blood 118 (21), 1666, 2011
12011
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