| RAD21 mutations cause a human cohesinopathy MA Deardorff, JJ Wilde, M Albrecht, E Dickinson, S Tennstedt, ... The American Journal of Human Genetics 90 (6), 1014-1027, 2012 | 324 | 2012 |
| Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation P Zhang, D Wang, Y Zhao, S Ren, K Gao, Z Ye, S Wang, CW Pan, Y Zhu, ... Nature medicine 23 (9), 1055-1062, 2017 | 264 | 2017 |
| Phosphorylated RB promotes cancer immunity by inhibiting NF-κB activation and PD-L1 expression X Jin, D Ding, Y Yan, H Li, B Wang, L Ma, Z Ye, T Ma, Q Wu, ... Molecular cell 73 (1), 22-35. e6, 2019 | 216 | 2019 |
| DUB3 promotes BET inhibitor resistance and cancer progression by deubiquitinating BRD4 X Jin, Y Yan, D Wang, D Ding, T Ma, Z Ye, R Jimenez, L Wang, H Wu, ... Molecular cell 71 (4), 592-605. e4, 2018 | 142 | 2018 |
| Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice H Xu, K Balakrishnan, J Malaterre, M Beasley, Y Yan, J Essers, ... PloS one 5 (8), e12112, 2010 | 127 | 2010 |
| Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers H Xu, M Yan, J Patra, R Natrajan, Y Yan, S Swagemakers, ... Breast Cancer Research 13, 1-10, 2011 | 110 | 2011 |
| Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression J Yang, X Jin, Y Yan, Y Shao, Y Pan, LR Roberts, J Zhang, H Huang, ... Scientific Reports 7 (1), 43864, 2017 | 104 | 2017 |
| RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas S Deb, H Xu, J Tuynman, J George, Y Yan, J Li, RL Ward, N Mortensen, ... British journal of cancer 110 (6), 1606-1613, 2014 | 98 | 2014 |
| Interplay among PI3K/AKT, PTEN/FOXO and AR signaling in prostate cancer Y Yan, H Huang Prostate cancer: Cellular and genetic mechanisms of disease development and …, 2019 | 85 | 2019 |
| Cohesin Rad21 mediates loss of heterozygosity and is upregulated via Wnt promoting transcriptional dysregulation in gastrointestinal tumors H Xu, Y Yan, S Deb, D Rangasamy, M Germann, J Malaterre, NC Eder, ... Cell reports 9 (5), 1781-1797, 2014 | 79 | 2014 |
| Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG J Shao, Y Yan, D Ding, DW Wang, Y He, Y Pan, W Yan, A Kharbanda, ... Adv Sci, 2021 | 75 | 2021 |
| The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer Y Yan, J Ma, D Wang, D Lin, X Pang, S Wang, Y Zhao, L Shi, H Xue, ... EMBO molecular medicine 11 (11), e10659, 2019 | 73 | 2019 |
| Loss of FOXO1 cooperates with TMPRSS2–ERG overexpression to promote prostate tumorigenesis and cell invasion Y Yang, AM Blee, D Wang, J An, Y Pan, Y Yan, T Ma, Y He, J Dugdale, ... Cancer research 77 (23), 6524-6537, 2017 | 65 | 2017 |
| FOXA1 overexpression suppresses interferon signaling and immune response in cancer Y He, L Wang, T Wei, YT Xiao, H Sheng, H Su, DP Hollern, X Zhang, J Ma, ... The Journal of clinical investigation 131 (14), 2021 | 62 | 2021 |
| TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer AM Blee, Y He, Y Yang, Z Ye, Y Yan, Y Pan, T Ma, J Dugdale, E Kuehn, ... Clinical Cancer Research 24 (18), 4551-4565, 2018 | 61 | 2018 |
| Dual inhibition of AKT‐mTOR and AR signaling by targeting HDAC3 in PTEN‐ or SPOP‐mutated prostate cancer Y Yan, J An, Y Yang, D Wu, Y Bai, W Cao, L Ma, J Chen, Z Yu, Y He, X Jin, ... EMBO molecular medicine 10 (4), e8478, 2018 | 53 | 2018 |
| HDAC5 loss impairs RB repression of pro-oncogenic genes and confers CDK4/6 inhibitor resistance in cancer Y Zhou, X Jin, J Ma, D Ding, Z Huang, H Sheng, Y Yan, Y Pan, T Wei, ... Cancer research 81 (6), 1486-1499, 2021 | 50 | 2021 |
| Induction of apoptosis and autophagic cell death by the vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde is accompanied by the cleavage of DNA-PKcs and rapid … YQ Yan, B Zhang, L Wang, YH Xie, T Peng, B Bai, PK Zhou Cancer letters 252 (2), 280-289, 2007 | 41 | 2007 |
| DNA damage promotes TMPRSS2-ERG oncoprotein destruction and prostate cancer suppression via signaling converged by GSK3β and WEE1 Z Hong, W Zhang, D Ding, Z Huang, Y Yan, W Cao, Y Pan, X Hou, ... Molecular Cell 79 (6), 1008-1023. e4, 2020 | 37 | 2020 |
| ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication D Wang, J Ma, MV Botuyan, G Cui, Y Yan, D Ding, Y Zhou, EW Krueger, ... Science Advances 7 (25), eabd9208, 2021 | 33 | 2021 |
