Sex-specific transcriptional signatures in human depression B Labonté, O Engmann, I Purushothaman, C Menard, J Wang, C Tan, ... Nature medicine 23 (9), 1102-1111, 2017 | 629 | 2017 |
De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder PJ Hamilton, NG Campbell, S Sharma, K Erreger, F Herborg Hansen, ... Molecular psychiatry 18 (12), 1315-1323, 2013 | 236 | 2013 |
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD FH Hansen, T Skjørringe, S Yasmeen, NV Arends, MA Sahai, K Erreger, ... The Journal of clinical investigation 124 (7), 3107-3120, 2014 | 156 | 2014 |
SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking E Bowton, C Saunders, IA Reddy, NG Campbell, PJ Hamilton, LK Henry, ... Translational psychiatry 4 (10), e464-e464, 2014 | 147 | 2014 |
Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia X Guo, PJ Hamilton, NJ Reish, JD Sweatt, CA Miller, G Rumbaugh Neuropsychopharmacology 34 (7), 1659-1672, 2009 | 145 | 2009 |
Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation D Sakrikar, MS Mazei-Robison, MA Mergy, NW Richtand, Q Han, ... Journal of Neuroscience 32 (16), 5385-5397, 2012 | 137 | 2012 |
PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein PJ Hamilton, AN Belovich, G Khelashvili, C Saunders, K Erreger, ... Nature chemical biology 10 (7), 582-589, 2014 | 133 | 2014 |
Epigenetics and addiction PJ Hamilton, EJ Nestler Current opinion in neurobiology 59, 128-136, 2019 | 122 | 2019 |
Sex-specific role for the long non-coding RNA LINC00473 in depression O Issler, YY van der Zee, A Ramakrishnan, J Wang, C Tan, YHE Loh, ... Neuron 106 (6), 912-926. e5, 2020 | 114 | 2020 |
Estrogen receptor α drives pro-resilient transcription in mouse models of depression ZS Lorsch, YHE Loh, I Purushothaman, DM Walker, EM Parise, M Salery, ... Nature communications 9 (1), 1116, 2018 | 102 | 2018 |
Targeted epigenetic remodeling of the Cdk5 gene in nucleus accumbens regulates cocaine-and stress-evoked behavior EA Heller, PJ Hamilton, DD Burek, SI Lombroso, CJ Peña, RL Neve, ... Journal of neuroscience 36 (17), 4690-4697, 2016 | 100 | 2016 |
Cell-type-specific epigenetic editing at the Fosb gene controls susceptibility to social defeat stress PJ Hamilton, DJ Burek, SI Lombroso, RL Neve, AJ Robison, EJ Nestler, ... Neuropsychopharmacology 43 (2), 272-284, 2018 | 98 | 2018 |
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex ZS Lorsch, PJ Hamilton, A Ramakrishnan, EM Parise, M Salery, ... Nature neuroscience 22 (9), 1413-1423, 2019 | 97 | 2019 |
Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4, 5-bisphosphate F Buchmayer, K Schicker, T Steinkellner, P Geier, G Stübiger, PJ Hamilton, ... Proceedings of the National Academy of Sciences 110 (28), 11642-11647, 2013 | 87 | 2013 |
Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors E Cartier, PJ Hamilton, AN Belovich, A Shekar, NG Campbell, C Saunders, ... EBioMedicine 2 (2), 135-146, 2015 | 80 | 2015 |
Silent synapses dictate cocaine memory destabilization and reconsolidation WJ Wright, NM Graziane, PA Neumann, PJ Hamilton, HM Cates, L Fuerst, ... Nature neuroscience 23 (1), 32-46, 2020 | 75 | 2020 |
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine EA Ribeiro, M Salery, JR Scarpa, ES Calipari, PJ Hamilton, SM Ku, ... Nature communications 9 (1), 1-10, 2018 | 49 | 2018 |
Chromatin-mediated alternative splicing regulates cocaine-reward behavior SJ Xu, SI Lombroso, DK Fischer, MD Carpenter, DM Marchione, ... Neuron 109 (18), 2943-2966. e8, 2021 | 47 | 2021 |
Cocaine-induced chromatin modifications associate with increased expression and three-dimensional looping of Auts2 O Engmann, B Labonté, A Mitchell, P Bashtrykov, ES Calipari, ... Biological psychiatry 82 (11), 794-805, 2017 | 45 | 2017 |
Opioid withdrawal produces sex-specific effects on fentanyl-versus-food choice and mesolimbic transcription EA Townsend, RK Kim, HL Robinson, SA Marsh, ML Banks, PJ Hamilton Biological psychiatry global open science 1 (2), 112-122, 2021 | 41 | 2021 |