| Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma M Yanae, M Tsubaki, T Satou, T Itoh, M Imano, Y Yamazoe, S Nishida Journal of Experimental & Clinical Cancer Research 30 (1), 1-8, 2011 | 140 | 2011 |
| Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway Y Kidera, M Tsubaki, Y Yamazoe, K Shoji, H Nakamura, M Ogaki, T Satou, ... Journal of Experimental & Clinical Cancer Research 29 (1), 127, 2010 | 119 | 2010 |
| Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines M Tsubaki, M Komai, S Fujimoto, T Itoh, M Imano, K Sakamoto, ... Journal of experimental & clinical cancer research 32, 1-9, 2013 | 116 | 2013 |
| Exercise increases neural stem cell proliferation surrounding the area of damage following rat traumatic brain injury T Itoh, M Imano, S Nishida, M Tsubaki, S Hashimoto, A Ito, T Satou Journal of neural transmission 118, 193-202, 2011 | 106 | 2011 |
| Edaravone protects against apoptotic neuronal cell death and improves cerebral function after traumatic brain injury in rats T Itoh, T Satou, S Nishida, M Tsubaki, M Imano, S Hashimoto, H Ito Neurochemical Research 35, 348-355, 2010 | 102 | 2010 |
| Exercise inhibits neuronal apoptosis and improves cerebral function following rat traumatic brain injury T Itoh, M Imano, S Nishida, M Tsubaki, S Hashimoto, A Ito, T Satou Journal of Neural Transmission 118, 1263-1272, 2011 | 101 | 2011 |
| Expression of amyloid precursor protein after rat traumatic brain injury T Itoh, T Satou, S Nishida, M Tsubaki, S Hashimoto, H Ito Neurological research 31 (1), 103-109, 2009 | 101 | 2009 |
| Macrophage inflammatory protein-1α (MIP-1α) enhances a receptor activator of nuclear factor κB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts … M Tsubaki, C Kato, M Manno, M Ogaki, T Satou, T Itoh, T Kusunoki, ... Molecular and cellular biochemistry 304, 53-60, 2007 | 95 | 2007 |
| Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways H Matsuoka, M Tsubaki, Y Yamazoe, M Ogaki, T Satou, T Itoh, T Kusunoki, ... Experimental cell research 315 (12), 2022-2032, 2009 | 93 | 2009 |
| Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma M Tsubaki, Y Yamazoe, M Yanae, T Satou, T Itoh, J Kaneko, Y Kidera, ... Cytokine 54 (1), 100-107, 2011 | 89 | 2011 |
| The relationship between SDF-1α/CXCR4 and neural stem cells appearing in damaged area after traumatic brain injury in rats T Itoh, T Satou, H Ishida, S Nishida, M Tsubaki, S Hashimoto, H Ito Neurological research 31 (1), 90-102, 2009 | 88 | 2009 |
| Induction of apoptosis in HL-60 cells treated with medicinal herbs S Nishida, S Kikuichi, S Yoshioka, M Tsubaki, Y Fujii, H Matsuda, M Kubo, ... The American journal of Chinese medicine 31 (04), 551-562, 2003 | 83 | 2003 |
| Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells M Tsubaki, T Satou, T Itoh, M Imano, M Komai, M Nishinobo, M Yamashita, ... Leukemia research 36 (10), 1315-1322, 2012 | 82 | 2012 |
| Mangiferin suppresses CIA by suppressing the expression of TNF-α, IL-6, IL-1β, and RANKL through inhibiting the activation of NF-κB and ERK1/2 M Tsubaki, T Takeda, T Kino, T Itoh, M Imano, G Tanabe, O Muraoka, ... American Journal of Translational Research 7 (8), 1371, 2015 | 81 | 2015 |
| Bisphosphonate-and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of … M Tsubaki, T Satou, T Itoh, M Imano, M Yanae, C Kato, R Takagoshi, ... Molecular and cellular endocrinology 361 (1-2), 219-231, 2012 | 75 | 2012 |
| Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells K Shoji, M Tsubaki, Y Yamazoe, T Satou, T Itoh, Y Kidera, Y Tanimori, ... Archives of pharmacal research 34, 469-475, 2011 | 74 | 2011 |
| The novel free radical scavenger, edaravone, increases neural stem cell number around the area of damage following rat traumatic brain injury T Itoh, T Satou, S Nishida, M Tsubaki, S Hashimoto, H Ito Neurotoxicity Research 16, 378-389, 2009 | 71 | 2009 |
| Nitrogen-containing bisphosphonates inhibit RANKL-and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation M Tsubaki, M Komai, T Itoh, M Imano, K Sakamoto, H Shimaoka, ... Journal of biomedical science 21 (1), 1-14, 2014 | 70 | 2014 |
| Overexpression of survivin via activation of ERK1/2, Akt, and NF-κB plays a central role in vincristine resistance in multiple myeloma cells M Tsubaki, T Takeda, N Ogawa, K Sakamoto, H Shimaoka, A Fujita, T Itoh, ... Leukemia research 39 (4), 445-452, 2015 | 67 | 2015 |
| Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway M Tsubaki, T Satou, T Itoh, M Imano, M Ogaki, M Yanae, S Nishida Toxicology and applied pharmacology 259 (3), 402-410, 2012 | 66 | 2012 |
