Oxidative stress, synaptic dysfunction, and Alzheimer’s disease E Tönnies, E Trushina Journal of Alzheimer's Disease 57 (4), 1105-1121, 2017 | 1461 | 2017 |
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro E Trushina, RB Dyer, JD Badger, D Ure, L Eide, DD Tran, BT Vrieze, ... Molecular and cellular biology 24 (18), 8195-8209, 2004 | 604 | 2004 |
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature reviews Drug discovery 19 (9), 609-633, 2020 | 567 | 2020 |
Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases E Trushina, CT McMurray Neuroscience 145 (4), 1233-1248, 2007 | 540 | 2007 |
Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer’s disease using metabolomics E Trushina, T Dutta, XMT Persson, MM Mielke, RC Petersen PloS one 8 (5), e63644, 2013 | 449 | 2013 |
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease E Trushina, E Nemutlu, S Zhang, T Christensen, J Camp, J Mesa, ... PloS one 7 (2), e32737, 2012 | 292 | 2012 |
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ... Neurobiology of disease 78, 172-195, 2015 | 257 | 2015 |
Application of metabolomics in Alzheimer’s disease JM Wilkins, E Trushina Frontiers in neurology 8, 719, 2018 | 232 | 2018 |
Recent advances in the application of metabolomics to Alzheimer's Disease E Trushina, MM Mielke Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 207 | 2014 |
Developing novel blood-based biomarkers for Alzheimer's disease HM Snyder, MC Carrillo, F Grodstein, K Henriksen, A Jeromin, ... Alzheimer's & Dementia 10 (1), 109-114, 2014 | 205 | 2014 |
Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease L Zhang, S Trushin, TA Christensen, BV Bachmeier, B Gateno, ... Scientific reports 6 (1), 18725, 2016 | 202 | 2016 |
Mitochondrial dynamics and transport in Alzheimer's disease PJ Flannery, E Trushina Molecular and Cellular Neuroscience 98, 109-120, 2019 | 162 | 2019 |
White matter lipids as a ketogenic fuel supply in aging female brain: implications for Alzheimer's disease LP Klosinski, J Yao, F Yin, AN Fonteh, MG Harrington, TA Christensen, ... EBioMedicine 2 (12), 1888-1904, 2015 | 148 | 2015 |
Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome M Arnold, K Nho, A Kueider-Paisley, T Massaro, K Huynh, B Brauner, ... Nature communications 11 (1), 1148, 2020 | 144 | 2020 |
Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo E Trushina, RD Singh, RB Dyer, S Cao, VH Shah, RG Parton, RE Pagano, ... Human molecular genetics 15 (24), 3578-3591, 2006 | 132 | 2006 |
Neurological abnormalities in caveolin-1 knock out mice E Trushina, J Du Charme, J Parisi, CT McMurray Behavioural brain research 172 (1), 24-32, 2006 | 118 | 2006 |
Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease E Trushina, MP Heldebrant, CM Perez-Terzic, R Bortolon, IV Kovtun, ... Proceedings of the National Academy of Sciences 100 (21), 12171-12176, 2003 | 112 | 2003 |
Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons NP Staff, JL Podratz, L Grassner, M Bader, J Paz, AM Knight, CL Loprinzi, ... Neurotoxicology 39, 124-131, 2013 | 104 | 2013 |
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease L Zhang, S Zhang, I Maezawa, S Trushin, P Minhas, M Pinto, LW Jin, ... EBioMedicine 2 (4), 294-305, 2015 | 99 | 2015 |
A hippo and fibroblast growth factor receptor autocrine pathway in cholangiocarcinoma S Rizvi, D Yamada, P Hirsova, SF Bronk, NW Werneburg, A Krishnan, ... Journal of Biological Chemistry 291 (15), 8031-8047, 2016 | 89 | 2016 |