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Emma Farley
Emma Farley
Assistant Professor, UC San Diego
在 ucsd.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Suboptimization of developmental enhancers
EK Farley, KM Olson, W Zhang, AJ Brandt, DS Rokhsar, MS Levine
Science 350 (6258), 325-328, 2015
3302015
Large-scale profiling reveals the influence of genetic variation on gene expression in human induced pluripotent stem cells
C DeBoever, H Li, D Jakubosky, P Benaglio, J Reyna, KM Olson, ...
Cell stem cell 20 (4), 533-546. e7, 2017
1772017
Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancers
EK Farley, KM Olson, W Zhang, DS Rokhsar, MS Levine
Proceedings of the National Academy of Sciences 113 (23), 6508-6513, 2016
1722016
3D genomics across the tree of life reveals condensin II as a determinant of architecture type
C Hoencamp, O Dudchenko, AMO Elbatsh, S Brahmachari, ...
Science 372 (6545), 984-989, 2021
1712021
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression
W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ...
Nature genetics 50 (4), 613-620, 2018
1482018
Enhancer grammar in development, evolution, and disease: dependencies and interplay
GA Jindal, EK Farley
Developmental cell 56 (5), 575-587, 2021
1002021
Doublesex and mab-3–related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate
N Gennet, E Gale, X Nan, E Farley, K Takacs, B Oberwallner, ...
Proceedings of the National Academy of Sciences 108 (22), 9131-9136, 2011
422011
Regulatory principles governing tissue specificity of developmental enhancers
EK Farley, KM Olson, MS Levine
Cold Spring Harbor symposia on quantitative biology 80, 27-32, 2015
262015
Functional genomic approaches to elucidate the role of enhancers during development
GE Ryan, EK Farley
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (2), e1467, 2020
192020
Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer
M D′ Antonio, D Weghorn, A D′ Antonio-Chronowska, F Coulet, ...
Nature communications 8 (1), 436, 2017
192017
Affinity-optimizing enhancer variants disrupt development
F Lim, JJ Solvason, GE Ryan, SH Le, GA Jindal, P Steffen, SK Jandu, ...
Nature 626 (7997), 151-159, 2024
152024
Single-nucleotide variants within heart enhancers increase binding affinity and disrupt heart development
GA Jindal, AT Bantle, JJ Solvason, JL Grudzien, A D’Antonio-Chronowska, ...
Developmental Cell 58 (21), 2206-2216. e5, 2023
132023
Diverse logics and grammar encode notochord enhancers
BP Song, MF Ragsac, K Tellez, GA Jindal, JL Grudzien, SH Le, EK Farley
Cell reports 42 (2), 2023
112023
Affinity-optimizing variants within the ZRS enhancer disrupt limb development
F Lim, GE Ryan, SH Le, JJ Solvason, P Steffen, EK Farley
BioRxiv, 2022.05. 27.493789, 2022
92022
HOT DNAs: a novel class of developmental enhancers
E Farley, M Levine
Genes & Development 26 (9), 873-876, 2012
92012
Effects of in ovo electroporation on endogenous gene expression: genome-wide analysis
EK Farley, E Gale, D Chambers, M Li
Neural Development 6, 1-13, 2011
72011
Conserved enhancers control notochord expression of vertebrate Brachyury
CL Kemmler, J Smolikova, HR Moran, BJ Mannion, D Knapp, F Lim, ...
Nature communications 14 (1), 6594, 2023
52023
Gene transfer in developing chick embryos: in ovo electroporation
EK Farley
Neural Development: Methods and Protocols, 141-150, 2013
52013
EUGENe: A Python toolkit for predictive analyses of regulatory sequences
A Klie, H Stites, T Jores, JJ Solvason, EK Farley, H Carter
bioRxiv, 2022.10. 24.513593, 2022
42022
Predictive analyses of regulatory sequences with EUGENe
A Klie, D Laub, JV Talwar, H Stites, T Jores, JJ Solvason, EK Farley, ...
Nature Computational Science 3 (11), 946-956, 2023
32023
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