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Muthukumar Karuppasamy PhD
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Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes
MK Mahapatra, M Karuppasamy, BM Sahoo
Reviews in Endocrine and Metabolic Disorders 23 (3), 521-539, 2022
862022
Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies
M Karuppasamy, M Mahapatra, S Yabanoglu, G Ucar, BN Sinha, A Basu, ...
Bioorganic & medicinal chemistry 18 (5), 1875-1881, 2010
672010
Therapeutic potential of semaglutide, a newer GLP-1 receptor agonist, in abating obesity, non-alcoholic steatohepatitis and neurodegenerative diseases: A narrative review
MK Mahapatra, M Karuppasamy, BM Sahoo
Pharmaceutical Research 39 (6), 1233-1248, 2022
572022
Evaluation of wound healing and antimicrobial potentials of Ixora coccinea root extract
N Selvaraj, B Lakshmanan, PM Mazumder, M Karuppasamy, SS Jena, ...
Asian Pacific Journal of Tropical Medicine 4 (12), 959-963, 2011
472011
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway
FF Gan, R Zhang, HL Ng, M Karuppasamy, W Seah, WH Yeap, SM Ong, ...
Food and chemical toxicology 116, 238-248, 2018
342018
Fundamental considerations in drug design
MK Mahapatra, M Karuppasamy
Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure …, 2022
252022
Ribisins and Certain Analogues Exert Neuroprotective Effects through Activation of the Keap1‐Nrf2‐ARE Pathway
SH Tan, M Karuppasamy, P Lan, Y Zhang, J Hu, X Lai, B Siok‐Cheng Lim, ...
ChemMedChem 17 (18), e202200292, 2022
42022
DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
A Samani, M Karuppasamy, KG English, CA Siler, Y Wang, JJ Widrick, ...
bioRxiv, 2023
22023
Standardization of zebrafish drug testing parameters for muscle diseases
M Karuppasamy, KG English, CA Henry, MC Manzini, JM Parant, ...
Disease Models & Mechanisms 17 (1), 2024
2024
P189 Dock7 is an essential driver of skeletal muscle health and function
K English, A Samani, K Becker, M Karupassamy, M Alexander
Neuromuscular Disorders 33, S112-S113, 2023
2023
P59 Generation and characterization of a novel XMEA mouse model and pharmacological evaluation of autophagy antagonists
M Karuppasamy, K English, V Sanders, M Lopez, G Kaur, L Worthey, ...
Neuromuscular Disorders 33, S73, 2023
2023
Restoration of brain dystrophin using tricyclo-DNA ASOs restores neurobehavioral deficits in DMD mice
M Karuppasamy, MS Alexander
Molecular Therapy-Nucleic Acids 32, 841-842, 2023
2023
Acknowledgment to the Reviewers of Journal of Developmental Biology in 2022
E Akat, P Ha, ECP Ambrósio, C Henry, R Andrade, H Hong, J Ball, M Horb, ...
2023
Exploration of Keap1-Nrf2-ARE Signaling Pathway Modulators as Potential Neuroprotectants
M Karuppasamy
PQDT-Global, 2018
2018
Biological Characterization of the Anti-Tumor Properties of Novel Dual-Target Inhibitors of Dihydrofolate Reductase and Thioredoxin Reductase
EH Chew, HL Ng, M Kjellander, M Karuppasamy, ASY Chong, WK Chui, ...
Free Radical Biology and Medicine 100, S119-S120, 2016
2016
Exploration of the Antioxidant and Nrf2 Inducing Properties of a Group of Small Molecule Compounds That Mimic Peptide Inhibitors of Keap1-Nrf2 Interaction
EH Chew, M Karuppasamy, Y Li, MY Lim, TA Vu, X Lai, H Bertrand, ...
Free Radical Biology and Medicine 1 (87), S88, 2015
2015
DOCK3 IS ESSENTIAL FOR NORMAL MUSCLE REGENERATION AND GLUCOSE METABOLISM
A SAMANI, Y WANG, KG ENGLISH, M KARUPPASAMY, JJ WIDRICK
The Role of DOCK3 In Normal Skeletal Muscle Function and Metabolism, 96, 0
How can India influence drug discovery and development
KS Rao, P Jayaram, M Karuppasamy
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