A patent review of arginine methyltransferase inhibitors (2010–2018) X Li, C Wang, H Jiang, C Luo Expert opinion on therapeutic patents 29 (2), 97-114, 2019 | 95 | 2019 |
Enhancement of cisplatin efficacy by lipid–CaO 2 nanocarrier-mediated comprehensive modulation of the tumor microenvironment C He, X Zhang, R Yan, P Zhao, Y Chen, M Li, C Chen, T Fan, Y Lu, ... Biomaterials science 7 (10), 4260-4272, 2019 | 56 | 2019 |
Development of potent type I protein arginine methyltransferase (PRMT) inhibitors of leukemia cell proliferation C Wang, H Jiang, J Jin, Y Xie, Z Chen, H Zhang, F Lian, YC Liu, C Zhang, ... Journal of medicinal chemistry 60 (21), 8888-8905, 2017 | 47 | 2017 |
Chromatin basis of the senescence-associated secretory phenotype X Hao, C Wang, R Zhang Trends in cell biology 32 (6), 513-526, 2022 | 44 | 2022 |
Role of 53BP1 in end protection and DNA synthesis at DNA breaks J Paiano, N Zolnerowich, W Wu, R Pavani, C Wang, H Li, L Zheng, ... Genes & development 35 (19-20), 1356-1367, 2021 | 42 | 2021 |
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma J Wang, C Wang, P Xu, X Li, Y Lu, D Jin, X Yin, H Jiang, J Huang, H Xiong, ... Theranostics 11 (11), 5387, 2021 | 42 | 2021 |
Current strategies and applications for precision drug design C Wang, P Xu, L Zhang, J Huang, K Zhu, C Luo Frontiers in pharmacology 9, 787, 2018 | 39 | 2018 |
Discovery of 1, 8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening H Xiong, J Han, J Wang, W Lu, C Wang, Y Chen, F Lian, N Zhang, YC Liu, ... European journal of medicinal chemistry 151, 740-751, 2018 | 37 | 2018 |
The SETDB1–TRIM28 complex suppresses antitumor immunity J Lin, D Guo, H Liu, W Zhou, C Wang, I Müller, AV Kossenkov, R Drapkin, ... Cancer immunology research 9 (12), 1413-1424, 2021 | 34 | 2021 |
Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues H Jiang, J Xing, C Wang, H Zhang, L Yue, X Wan, W Chen, H Ding, Y Xie, ... Organic & Biomolecular Chemistry 15 (44), 9352-9361, 2017 | 29 | 2017 |
A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2) J Lu, L Hu, J Cheng, D Fang, C Wang, K Yu, H Jiang, Q Cui, Y Xu, C Luo Physical Chemistry Chemical Physics 18 (6), 4728-4738, 2016 | 27 | 2016 |
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors W Lu, H Xiong, Y Chen, C Wang, H Zhang, P Xu, J Han, S Xiao, H Ding, ... Bioorganic & Medicinal Chemistry 26 (20), 5397-5407, 2018 | 25 | 2018 |
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys M Wu, P Lin, L Li, D Chen, X Yang, L Xu, B Zhou, C Wang, Y Zhang, ... The FASEB Journal 33 (6), 6948-6956, 2019 | 21 | 2019 |
Design, synthesis and biological evaluation of pyrazolylaminoquinazoline derivatives as highly potent pan-fibroblast growth factor receptor inhibitors J Fan, Y Dai, J Shao, X Peng, C Wang, S Cao, B Zhao, J Ai, M Geng, ... Bioorganic & Medicinal Chemistry Letters 26 (11), 2594-2599, 2016 | 16 | 2016 |
Targeting cellular senescence to combat cancer and ageing C Wang, X Hao, R Zhang Molecular oncology 16 (18), 3319-3332, 2022 | 10 | 2022 |
Discovery and development of small molecules targeting epigenetic enzymes with computational methods F Meng, C Wang, W Wan, W Lu, W Lu, C Luo Epi-Informatics, 75-112, 2016 | 7 | 2016 |
Discovery of 1, 3‐Diaryl‐pyridones as Potent VEGFR‐2 Inhibitors: Design, Synthesis, and Biological Evaluation W Yan, Z Huang, Z Wang, S Cao, L Tong, T Zhang, C Wang, L Zhou, ... Chemical Biology & Drug Design 87 (5), 694-703, 2016 | 6 | 2016 |
Renal asymmetric dimethylarginine inhibits fibrosis M Wu, M Yuan, Y Wang, B Tan, D Huang, C Wang, Y Zou, C Ye FEBS Open bio 10 (10), 2003-2009, 2020 | 4 | 2020 |