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Jacob T Polaski
Jacob T Polaski
Postdoctoral Research Associate, Huntsman Cancer Institute
在 hci.utah.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
B12 cofactors directly stabilize an mRNA regulatory switch
JE Johnson Jr, FE Reyes, JT Polaski, RT Batey
Nature 492 (7427), 133-137, 2012
2262012
Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors
EB Porter, JT Polaski, MM Morck, RT Batey
Nature chemical biology 13 (3), 295-301, 2017
1382017
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells
E Braselmann, AJ Wierzba, JT Polaski, M Chromiński, ZE Holmes, ...
Nature chemical biology 14 (10), 964-971, 2018
1272018
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons
JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ...
Nature Genetics 52 (1), 84-94, 2020
882020
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ...
Nature Genetics 53 (5), 707-718, 2021
822021
Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin
JT Polaski, SM Webster, JE Johnson, RT Batey
Journal of Biological Chemistry 292 (28), 11650-11658, 2017
582017
Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch
ED Holmstrom, JT Polaski, RT Batey, DJ Nesbitt
Journal of the American Chemical Society 136 (48), 16832-16843, 2014
502014
Mechanistic insights into cofactor-dependent coupling of RNA folding and mRNA transcription/translation by a cobalamin riboswitch
JT Polaski, ED Holmstrom, DJ Nesbitt, RT Batey
Cell reports 15 (5), 1100-1110, 2016
492016
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells
K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ...
Nature biotechnology 40 (7), 1103-1113, 2022
422022
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations
J Pangallo, JJ Kiladjian, B Cassinat, A Renneville, J Taylor, JT Polaski, ...
Blood, The Journal of the American Society of Hematology 135 (13), 1032-1043, 2020
202020
A highly coupled network of tertiary interactions in the SAM-I riboswitch and their role in regulatory tuning
C Wostenberg, P Ceres, JT Polaski, RT Batey
Journal of molecular biology 427 (22), 3473-3490, 2015
142015
The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
JT Polaski, DB Udy, LF Escobar-Hoyos, G Askan, SD Leach, A Ventura, ...
Elife 10, e62209, 2021
122021
A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity
JT Polaski, OA Kletzien, LK Drogalis, RT Batey
Nucleic acids research 46 (17), 9094-9105, 2018
112018
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs
S Arnesen, JT Polaski, Z Blanchard, KS Osborne, AL Welm, ...
NAR cancer 5 (2), zcad027, 2023
32023
Characterization of HCI-EC-23 a novel estrogen-and progesterone-responsive endometrial cancer cell line
CM Rush, Z Blanchard, JT Polaski, KS Osborne, K Osby, JM Vahrenkamp, ...
Scientific reports 12 (1), 19731, 2022
32022
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