B12 cofactors directly stabilize an mRNA regulatory switch JE Johnson Jr, FE Reyes, JT Polaski, RT Batey Nature 492 (7427), 133-137, 2012 | 226 | 2012 |
Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors EB Porter, JT Polaski, MM Morck, RT Batey Nature chemical biology 13 (3), 295-301, 2017 | 138 | 2017 |
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells E Braselmann, AJ Wierzba, JT Polaski, M Chromiński, ZE Holmes, ... Nature chemical biology 14 (10), 964-971, 2018 | 127 | 2018 |
RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons JD Thomas, JT Polaski, Q Feng, EJ De Neef, ER Hoppe, MV McSharry, ... Nature Genetics 52 (1), 84-94, 2020 | 88 | 2020 |
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ... Nature Genetics 53 (5), 707-718, 2021 | 82 | 2021 |
Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin JT Polaski, SM Webster, JE Johnson, RT Batey Journal of Biological Chemistry 292 (28), 11650-11658, 2017 | 58 | 2017 |
Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch ED Holmstrom, JT Polaski, RT Batey, DJ Nesbitt Journal of the American Chemical Society 136 (48), 16832-16843, 2014 | 50 | 2014 |
Mechanistic insights into cofactor-dependent coupling of RNA folding and mRNA transcription/translation by a cobalamin riboswitch JT Polaski, ED Holmstrom, DJ Nesbitt, RT Batey Cell reports 15 (5), 1100-1110, 2016 | 49 | 2016 |
Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells K North, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl, JP Bewersdorf, ... Nature biotechnology 40 (7), 1103-1113, 2022 | 42 | 2022 |
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations J Pangallo, JJ Kiladjian, B Cassinat, A Renneville, J Taylor, JT Polaski, ... Blood, The Journal of the American Society of Hematology 135 (13), 1032-1043, 2020 | 20 | 2020 |
A highly coupled network of tertiary interactions in the SAM-I riboswitch and their role in regulatory tuning C Wostenberg, P Ceres, JT Polaski, RT Batey Journal of molecular biology 427 (22), 3473-3490, 2015 | 14 | 2015 |
The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma JT Polaski, DB Udy, LF Escobar-Hoyos, G Askan, SD Leach, A Ventura, ... Elife 10, e62209, 2021 | 12 | 2021 |
A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity JT Polaski, OA Kletzien, LK Drogalis, RT Batey Nucleic acids research 46 (17), 9094-9105, 2018 | 11 | 2018 |
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs S Arnesen, JT Polaski, Z Blanchard, KS Osborne, AL Welm, ... NAR cancer 5 (2), zcad027, 2023 | 3 | 2023 |
Characterization of HCI-EC-23 a novel estrogen-and progesterone-responsive endometrial cancer cell line CM Rush, Z Blanchard, JT Polaski, KS Osborne, K Osby, JM Vahrenkamp, ... Scientific reports 12 (1), 19731, 2022 | 3 | 2022 |