Cyclic [G (2′, 5′) pA (3′, 5′) p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase P Gao, M Ascano, Y Wu, W Barchet, BL Gaffney, T Zillinger, AA Serganov, ... Cell 153 (5), 1094-1107, 2013 | 990 | 2013 |
The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Y Liu, MD Cheney, JJ Gaudet, M Chruszcz, SM Lukasik, D Sugiyama, ... Cancer cell 9 (4), 249-260, 2006 | 181 | 2006 |
Unequivocal determination of complex molecular structures using anisotropic NMR measurements Y Liu, J Saurí, E Mevers, MW Peczuh, H Hiemstra, J Clardy, GE Martin, ... Science 356 (6333), eaam5349, 2017 | 161 | 2017 |
Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity Y Liu, W Chen, J Gaudet, MD Cheney, L Roudaia, T Cierpicki, RC Klet, ... Cancer cell 11 (6), 483-497, 2007 | 146 | 2007 |
Dynamic structure of membrane-anchored Arf• GTP Y Liu, RA Kahn, JH Prestegard Nature structural & molecular biology 17 (7), 876-881, 2010 | 145 | 2010 |
Structure and membrane interaction of myristoylated ARF1 Y Liu, RA Kahn, JH Prestegard Structure 17 (1), 79-87, 2009 | 138 | 2009 |
Application of anisotropic NMR parameters to the confirmation of molecular structure Y Liu, A Navarro-Vázquez, RR Gil, C Griesinger, GE Martin, ... Nature protocols 14 (1), 217-247, 2019 | 121 | 2019 |
Determination of relative configuration from residual chemical shift anisotropy N Nath, M Schmidt, RR Gil, RT Williamson, GE Martin, ... Journal of the American Chemical Society 138 (30), 9548-9556, 2016 | 108 | 2016 |
Homodimericin A: A complex hexacyclic fungal metabolite E Mevers, J Saurí, Y Liu, A Moser, TR Ramadhar, M Varlan, ... Journal of the American Chemical Society 138 (38), 12324-12327, 2016 | 96 | 2016 |
CBFβ allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium J Yan, Y Liu, SM Lukasik, NA Speck, JH Bushweller Nature structural & molecular biology 11 (9), 901-906, 2004 | 71 | 2004 |
A device for the measurement of residual chemical shift anisotropy and residual dipolar coupling in soluble and membrane-associated proteins Y Liu, JH Prestegard Journal of biomolecular NMR 47, 249-258, 2010 | 67 | 2010 |
Unequivocal determination of caulamidines A and B: Application and validation of new tools in the structure elucidation tool box DJ Milanowski, N Oku, LK Cartner, HR Bokesch, RT Williamson, J Saurí, ... Chemical Science 9 (2), 307-314, 2018 | 64 | 2018 |
Compositions and methods for altering second messenger signaling D Patel, T Tuschl, M Ascano, Y Wu, Y Liu, W Barchet, G Hartmann, ... US Patent 9,840,533, 2017 | 55 | 2017 |
Interaction of Fapp1 with Arf1 and PI4P at a membrane surface: an example of coincidence detection Y Liu, RA Kahn, JH Prestegard Structure 22 (3), 421-430, 2014 | 45 | 2014 |
Measurement of one and two bond N–C couplings in large proteins by TROSY-based J-modulation experiments Y Liu, JH Prestegard Journal of magnetic resonance 200 (1), 109-118, 2009 | 41 | 2009 |
Enhanced measurement of residual chemical shift anisotropy for small molecule structure elucidation Y Liu, RD Cohen, KR Gustafson, GE Martin, RT Williamson Chemical communications 54 (34), 4254-4257, 2018 | 40 | 2018 |
Complex macrocycle exploration: parallel, heuristic, and constraint-based conformer generation using ForceGen AN Jain, AE Cleves, Q Gao, X Wang, Y Liu, EC Sherer, MY Reibarkh Journal of computer-aided molecular design 33, 531-558, 2019 | 34 | 2019 |
Optimal mutation sites for PRE data collection and membrane protein structure prediction H Chen, F Ji, V Olman, CK Mobley, Y Liu, Y Zhou, JH Bushweller, ... Structure 19 (4), 484-495, 2011 | 33 | 2011 |
Direct measurement of dipole–dipole/CSA cross-correlated relaxation by a constant-time experiment Y Liu, JH Prestegard Journal of Magnetic Resonance 193 (1), 23-31, 2008 | 32 | 2008 |
PBLG as a versatile liquid crystalline medium for anisotropic NMR data acquisition IE Ndukwe, X Wang, I Pelczer, M Reibarkh, RT Williamson, Y Liu, ... Chemical Communications 55 (30), 4327-4330, 2019 | 31 | 2019 |