Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle ZA Bornholdt, T Noda, DM Abelson, P Halfmann, MR Wood, Y Kawaoka, ... Cell 154 (4), 763-774, 2013 | 259 | 2013 |
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak ZA Bornholdt, HL Turner, CD Murin, W Li, D Sok, CA Souders, AE Piper, ... Science 351 (6277), 1078-1083, 2016 | 229 | 2016 |
Structures of protective antibodies reveal sites of vulnerability on Ebola virus CD Murin, ML Fusco, ZA Bornholdt, X Qiu, GG Olinger, L Zeitlin, ... Proceedings of the National Academy of Sciences 111 (48), 17182-17187, 2014 | 217 | 2014 |
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus ZA Bornholdt, BVV Prasad Nature 456 (7224), 985-988, 2008 | 208 | 2008 |
X-ray structure of influenza virus NS1 effector domain ZA Bornholdt, BVV Prasad Nature structural & molecular biology 13 (6), 559-560, 2006 | 182 | 2006 |
Mechanism of human antibody-mediated neutralization of Marburg virus AI Flyak, PA Ilinykh, CD Murin, T Garron, X Shen, ML Fusco, T Hashiguchi, ... Cell 160 (5), 893-903, 2015 | 161 | 2015 |
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression CR Kimberlin, ZA Bornholdt, S Li, VL Woods Jr, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 107 (1), 314-319, 2010 | 160 | 2010 |
The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold APP Zhang, ZA Bornholdt, T Liu, DM Abelson, DE Lee, S Li, VL Woods Jr, ... PLoS pathogens 8 (2), e1002550, 2012 | 153 | 2012 |
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ... Cell 169 (5), 878-890. e15, 2017 | 152 | 2017 |
Structural basis for Marburg virus neutralization by a cross-reactive human antibody T Hashiguchi, ML Fusco, ZA Bornholdt, JE Lee, AI Flyak, R Matsuoka, ... Cell 160 (5), 904-912, 2015 | 140 | 2015 |
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ... Science 354 (6310), 350-354, 2016 | 127 | 2016 |
Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies ZA Bornholdt, E Ndungo, ML Fusco, S Bale, AI Flyak, JE Crowe Jr, ... MBio 7 (1), 10.1128/mbio. 02154-15, 2016 | 111 | 2016 |
The influenza A virus protein NS1 displays structural polymorphism B Carrillo, JM Choi, ZA Bornholdt, B Sankaran, AP Rice, BVV Prasad Journal of virology 88 (8), 4113-4122, 2014 | 103 | 2014 |
Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection AZ Wec, ZA Bornholdt, S He, AS Herbert, E Goodwin, AS Wirchnianski, ... Cell host & microbe 25 (1), 39-48. e5, 2019 | 96 | 2019 |
A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates ZA Bornholdt, AS Herbert, CE Mire, S He, RW Cross, AZ Wec, ... Cell host & microbe 25 (1), 49-58. e5, 2019 | 90 | 2019 |
Crystal structure of the Nipah virus phosphoprotein tetramerization domain JF Bruhn, KC Barnett, J Bibby, JMH Thomas, RM Keegan, DJ Rigden, ... Journal of virology 88 (1), 758-762, 2014 | 90 | 2014 |
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism S Bale, JP Julien, ZA Bornholdt, CR Kimberlin, P Halfmann, ... Public Library of Science 8 (9), e1002916, 2012 | 89 | 2012 |
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine AZ Wec, D Haslwanter, YN Abdiche, L Shehata, N Pedreño-Lopez, ... Proceedings of the National Academy of Sciences 117 (12), 6675-6685, 2020 | 88 | 2020 |
Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism S Bale, JP Julien, ZA Bornholdt, AS Krois, IA Wilson, EO Saphire Journal of virology 87 (18), 10385-10388, 2013 | 67 | 2013 |
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever JM Fels, DP Maurer, AS Herbert, AS Wirchnianski, O Vergnolle, RW Cross, ... Cell 184 (13), 3486-3501. e21, 2021 | 53 | 2021 |