Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 981 | 2012 |
Subtypes of medulloblastoma have distinct developmental origins P Gibson, Y Tong, G Robinson, MC Thompson, DS Currle, C Eden, ... Nature 468 (7327), 1095-1099, 2010 | 943 | 2010 |
In vivo loss of telomeric repeats with age in humans J Lindsey, NI McGill, LA Lindsey, DK Green, HJ Cooke Mutation Research/DNAging 256 (1), 45-48, 1991 | 651 | 1991 |
β-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee DW Ellison, OE Onilude, JC Lindsey, ME Lusher, CL Weston, RE Taylor, ... Journal of Clinical Oncology 23 (31), 7951-7957, 2005 | 538 | 2005 |
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ... Journal of Clinical Oncology 31 (23), 2927-2935, 2013 | 524 | 2013 |
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study EC Schwalbe, JC Lindsey, S Nakjang, S Crosier, AJ Smith, D Hicks, ... The Lancet Oncology 18 (7), 958-971, 2017 | 516 | 2017 |
Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of clinical oncology 32 (9), 886-896, 2014 | 363 | 2014 |
Wnt/wingless pathway activation and chromosome 6 loss characterise a distinct molecular sub-group of medulloblastomas associated with a favourable prognosis SC Clifford, ME Lusher, JC Lindsey, JA Langdon, RJ Gilbertson, ... Cell cycle 5 (22), 2666-2670, 2006 | 357 | 2006 |
Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 348 | 2016 |
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes T Sharma, EC Schwalbe, D Williamson, M Sill, V Hovestadt, M Mynarek, ... Acta neuropathologica 138, 309-326, 2019 | 254 | 2019 |
Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease RM Hill, S Kuijper, JC Lindsey, K Petrie, EC Schwalbe, K Barker, ... Cancer cell 27 (1), 72-84, 2015 | 216 | 2015 |
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies EC Schwalbe, D Williamson, JC Lindsey, D Hamilton, SL Ryan, ... Acta neuropathologica 125, 359-371, 2013 | 188 | 2013 |
Mutation analysis of the spastin gene (SPG4) in patients with hereditary spastic paraparesis JC Lindsey, ME Lusher, CJ McDermott, KD White, E Reid, ... Journal of medical genetics 37 (10), 759-765, 2000 | 155 | 2000 |
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling JC Lindsey, ME Lusher, JA Anderton, S Bailey, RJ Gilbertson, ... Carcinogenesis 25 (5), 661-668, 2004 | 141 | 2004 |
Clinical and pathologic findings in hereditary spastic paraparesis with spastin mutation KD White, PG Ince, M Lusher, J Lindsey, M Cookson, R Bashir, PJ Shaw, ... Neurology 55 (1), 89-94, 2000 | 128 | 2000 |
The structure of a subterminal repeated sequence present on many human chromosomes S Cross, J Lindsey, J Fantes, S McKay, N McGill, H Cooke Nucleic acids research 18 (22), 6649-6657, 1990 | 128 | 1990 |
Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development ME Lusher, JC Lindsey, F Latif, ADJ Pearson, DW Ellison, SC Clifford Cancer research 62 (20), 5906-5911, 2002 | 121 | 2002 |
Paraplegin gene analysis in hereditary spastic paraparesis (HSP) pedigrees in northeast England CJ McDermott, RK Dayaratne, J Tomkins, ME Lusher, JC Lindsey, ... Neurology 56 (4), 467-471, 2001 | 108 | 2001 |
Rapid diagnosis of medulloblastoma molecular subgroups EC Schwalbe, JC Lindsey, D Straughton, TL Hogg, M Cole, H Megahed, ... Clinical cancer research 17 (7), 1883-1894, 2011 | 104 | 2011 |
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity Y Grabovska, A Mackay, P O’Hare, S Crosier, M Finetti, EC Schwalbe, ... Nature communications 11 (1), 4324, 2020 | 101 | 2020 |