| ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats H Nishitoh, A Matsuzawa, K Tobiume, K Saegusa, K Takeda, K Inoue, ... Genes & development 16 (11), 1345-1355, 2002 | 1665 | 2002 |
| ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis K Tobiume, A Matsuzawa, T Takahashi, H Nishitoh, K Morita, K Takeda, ... EMBO reports, 2001 | 1437 | 2001 |
| ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity A Matsuzawa, K Saegusa, T Noguchi, C Sadamitsu, H Nishitoh, S Nagai, ... Nature immunology 6 (6), 587-592, 2005 | 754 | 2005 |
| Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling S Vallabhapurapu, A Matsuzawa, WZ Zhang, PH Tseng, JJ Keats, ... Nature immunology 9 (12), 1364-1370, 2008 | 729 | 2008 |
| ALS-linked mutant SOD1 induces ER stress-and ASK1-dependent motor neuron death by targeting Derlin-1 H Nishitoh, H Kadowaki, A Nagai, T Maruyama, T Yokota, H Fukutomi, ... Genes & development 22 (11), 1451-1464, 2008 | 614 | 2008 |
| Hepatocyte necrosis induced by oxidative stress and IL-1α release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis T Sakurai, G He, A Matsuzawa, GY Yu, S Maeda, G Hardiman, M Karin Cancer cell 14 (2), 156-165, 2008 | 580 | 2008 |
| Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling A Matsuzawa, H Ichijo Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (11), 1325-1336, 2008 | 574 | 2008 |
| Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation H Kadowaki, H Nishitoh, F Urano, C Sadamitsu, A Matsuzawa, K Takeda, ... Cell Death & Differentiation 12 (1), 19-24, 2005 | 495 | 2005 |
| Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines PH Tseng, A Matsuzawa, W Zhang, T Mino, DAA Vignali, M Karin Nature immunology 11 (1), 70-75, 2010 | 482 | 2010 |
| The ASK1-MAP kinase cascades in mammalian stress response J Matsukawa, A Matsuzawa, K Takeda, H Ichijo The Journal of biochemistry 136 (3), 261-265, 2004 | 420 | 2004 |
| Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation T Hatai, A Matsuzawa, S Inoshita, Y Mochida, T Kuroda, K Sakamaki, ... Journal of Biological Chemistry 275 (34), 26576-26581, 2000 | 413 | 2000 |
| Stress-responsive protein kinases in redox-regulated apoptosis signaling A Matsuzawa, H Ichijo Antioxidants & redox signaling 7 (3-4), 472-481, 2005 | 356 | 2005 |
| Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1 G Fujino, T Noguchi, A Matsuzawa, S Yamauchi, M Saitoh, K Takeda, ... Molecular and cellular biology, 2007 | 340 | 2007 |
| Physiological roles of ASK1-mediated signal transduction in oxidative stress-and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice A Matsuzawa, H Nishitoh, K Tobiume, K Takeda, H Ichijo Antioxidants and Redox Signaling 4 (3), 415-425, 2002 | 308 | 2002 |
| Roles of MAPKKK ASK1 in stress-induced cell death K Takeda, A Matsuzawa, H Nishitoh, H Ichijo Cell structure and function 28 (1), 23-29, 2003 | 290 | 2003 |
| Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II–induced cardiac hypertrophy and remodeling Y Izumiya, S Kim, Y Izumi, K Yoshida, M Yoshiyama, A Matsuzawa, ... Circulation Research 93 (9), 874-883, 2003 | 272 | 2003 |
| Essential cytoplasmic translocation of a cytokine receptor–assembled signaling complex A Matsuzawa, PH Tseng, S Vallabhapurapu, JL Luo, W Zhang, H Wang, ... Science 321 (5889), 663-668, 2008 | 264 | 2008 |
| Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced … T Noguchi, K Takeda, A Matsuzawa, K Saegusa, H Nakano, J Gohda, ... Journal of Biological Chemistry 280 (44), 37033-37040, 2005 | 260 | 2005 |
| Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis O Yamaguchi, T Watanabe, K Nishida, K Kashiwase, Y Higuchi, T Takeda, ... The Journal of clinical investigation 114 (7), 937-943, 2004 | 242 | 2004 |
| Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1 A Matsuzawa, H Ichijo The journal of biochemistry 130 (1), 1-8, 2001 | 223 | 2001 |
