Characterization of a mutant Escherichia coli heat-labile toxin, LT (R192G/L211A), as a safe and effective oral adjuvant EB Norton, LB Lawson, LC Freytag, JD Clements Clinical and Vaccine Immunology 18 (4), 546-551, 2011 | 230 | 2011 |
Defending the mucosa: adjuvant and carrier formulations for mucosal immunity LB Lawson, EB Norton, JD Clements Current opinion in immunology 23 (3), 414-420, 2011 | 151 | 2011 |
The mucosal vaccine adjuvant LT (R192G/L211A) or dmLT JD Clements, EB Norton MSphere 3 (4), 10.1128/msphere. 00215-18, 2018 | 121 | 2018 |
The A subunit of Escherichia coli heat-labile enterotoxin functions as a mucosal adjuvant and promotes IgG2a, IgA, and Th17 responses to vaccine antigens EB Norton, LB Lawson, Z Mahdi, LC Freytag, JD Clements Infection and immunity 80 (7), 2426-2435, 2012 | 103 | 2012 |
The novel adjuvant dmLT promotes dose sparing, mucosal immunity and longevity of antibody responses to the inactivated polio vaccine in a murine model EB Norton, DL Bauer, WC Weldon, MS Oberste, LB Lawson, JD Clements Vaccine 33 (16), 1909-1915, 2015 | 81 | 2015 |
Prophylactic administration of bacterially derived immunomodulators improves the outcome of influenza virus infection in a murine model EB Norton, JD Clements, TG Voss, L Cárdenas-Freytag Journal of virology 84 (6), 2983-2995, 2010 | 72 | 2010 |
Human cytomegalovirus alters host cell mitochondrial function during acute infection JA Combs, EB Norton, ZR Saifudeen, KHZ Bentrup, PV Katakam, ... Journal of Virology 94 (2), 10.1128/jvi. 01183-19, 2020 | 62 | 2020 |
Clinical predictors of bloodstream infections and mortality in hospitalized Malawian children EB Norton, LK Archibald, OC Nwanyanwu, PN Kazembe, H Dobbie, ... The Pediatric infectious disease journal 23 (2), 145-151, 2004 | 53 | 2004 |
Clinical and Immune Impact of Mycobacterium bovis BCG Vaccination Scarring J Jason, LK Archibald, OC Nwanyanwu, PN Kazembe, JA Chatt, E Norton, ... Infection and immunity 70 (11), 6188-6195, 2002 | 53 | 2002 |
Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system JA White, JS Blum, NA Hosken, JO Marshak, L Duncan, C Zhu, EB Norton, ... Human vaccines & immunotherapeutics 10 (12), 3611-3621, 2014 | 47 | 2014 |
Evaluating the A-Subunit of the Heat-Labile Toxin (LT) As an Immunogen and a Protective Antigen Against Enterotoxigenic Escherichia coli (ETEC) EB Norton, LM Branco, JD Clements PloS one 10 (8), e0136302, 2015 | 40 | 2015 |
Simultaneous exposure to Escherichia coli heat-labile and heat-stable enterotoxins increases fluid secretion and alters cyclic nucleotide and cytokine production by intestinal … LT Read, RW Hahn, CC Thompson, DL Bauer, EB Norton, JD Clements Infection and immunity 82 (12), 5308-5316, 2014 | 39 | 2014 |
An ACE2-dependent Sarbecovirus in Russian bats is resistant to SARS-CoV-2 vaccines SN Seifert, S Bai, S Fawcett, EB Norton, KJ Zwezdaryk, J Robinson, ... PLoS Pathogens 18 (9), e1010828, 2022 | 38* | 2022 |
Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy A Bhattacharjee, AHP Burr, AE Overacre-Delgoffe, JT Tometich, D Yang, ... Immunity 54 (8), 1745-1757. e7, 2021 | 38 | 2021 |
Vaccine-driven lung TRM cells provide immunity against Klebsiella via fibroblast IL-17R signaling N Iwanaga, K Chen, H Yang, S Lu, JP Hoffmann, A Wanek, JE McCombs, ... Science immunology 6 (63), eabf1198, 2021 | 36 | 2021 |
Mesenchymal stem cells as a novel vaccine platform SL Tomchuck, EB Norton, RF Garry, BA Bunnell, CA Morris, LC Freytag, ... Frontiers in cellular and infection microbiology 2, 140, 2012 | 35 | 2012 |
Functional changes in cellular fibronectin from late passage fibroblasts in vitro S Chandrasekhar, E Norton, AJT Millis, CS Izzard Cell biology international reports 7 (1), 11-21, 1983 | 31 | 1983 |
LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice E Valli, AJ Harriett, MK Nowakowska, RL Baudier, WB Provosty, ... Scientific Reports 9 (1), 15128, 2019 | 30 | 2019 |
Distribution and quantity of sites of John Cunningham virus persistence in immunologically healthy patients: correlation with John Cunningham virus antibody and urine John … JR Berger, CS Miller, RJ Danaher, K Doyle, KJ Simon, E Norton, L Gorelik, ... JAMA neurology 74 (4), 437-444, 2017 | 26 | 2017 |
Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection Z Huang, B Ning, HS Yang, BM Youngquist, A Niu, CJ Lyon, ... The Journal of Clinical Investigation 131 (7), 2021 | 23 | 2021 |