Hypothalamic inflammation in obesity and metabolic disease A Jais, JC Brüning The Journal of clinical investigation 127 (1), 24-32, 2017 | 415 | 2017 |
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man A Jais, E Einwallner, O Sharif, K Gossens, TTH Lu, SM Soyal, D Medgyesi, ... Cell 158 (1), 25-40, 2014 | 301 | 2014 |
Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity A Jais, M Solas, H Backes, B Chaurasia, A Kleinridders, S Theurich, ... Cell 165 (4), 882-895, 2016 | 241 | 2016 |
CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity P Hammerschmidt, D Ostkotte, H Nolte, MJ Gerl, A Jais, HL Brunner, ... Cell 177 (6), 1536-1552. e23, 2019 | 225 | 2019 |
Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells CCF Homem, V Steinmann, TR Burkard, A Jais, H Esterbauer, ... Cell 158 (4), 874-888, 2014 | 216 | 2014 |
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ... Nature 563 (7732), 564-568, 2018 | 210 | 2018 |
CerS1-derived C18: 0 ceramide in skeletal muscle promotes obesity-induced insulin resistance SM Turpin-Nolan, P Hammerschmidt, W Chen, A Jais, K Timper, ... Cell Reports 26 (1), 1-10. e7, 2019 | 142 | 2019 |
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing S Willenborg, DE Sanin, A Jais, X Ding, T Ulas, J Nüchel, M Popović, ... Cell metabolism 33 (12), 2398-2414. e9, 2021 | 125 | 2021 |
Arcuate nucleus-dependent regulation of metabolism—pathways to obesity and diabetes mellitus A Jais, JC Brüning Endocrine reviews 43 (2), 314-328, 2022 | 117 | 2022 |
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage MJ Perugorria, A Esparza-Baquer, F Oakley, I Labiano, A Korosec, A Jais, ... Gut 68 (3), 533-546, 2019 | 110 | 2019 |
Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesion S Tauber, A Jais, M Jeitler, S Haider, J Husa, J Lindroos, M Knöfler, ... Molecular cancer 9, 1-16, 2010 | 89 | 2010 |
Identification of ALK in Thinness M Orthofer, A Valsesia, R Mägi, QP Wang, J Kaczanowska, I Kozieradzki, ... Cell 181 (6), 1246-1262. e22, 2020 | 87 | 2020 |
PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding A Jais, L Paeger, T Sotelo-Hitschfeld, S Bremser, M Prinzensteiner, ... Neuron 106 (6), 1009-1025. e10, 2020 | 84 | 2020 |
AIF-regulated oxidative phosphorylation supports lung cancer development S Rao, L Mondragón, B Pranjic, T Hanada, G Stoll, T Köcher, P Zhang, ... Cell research 29 (7), 579-591, 2019 | 75 | 2019 |
VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: consequences for cognitive function in humans R Schüler, N Seebeck, MA Osterhoff, V Witte, A Flöel, A Busjahn, A Jais, ... Molecular metabolism 11, 129-136, 2018 | 62 | 2018 |
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis J Todoric, B Strobl, A Jais, N Boucheron, M Bayer, S Amann, J Lindroos, ... Diabetes 60 (6), 1668-1676, 2011 | 56 | 2011 |
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity M Porniece Kumar, AL Cremer, P Klemm, L Steuernagel, S Sundaram, ... Nature metabolism 3 (12), 1662-1679, 2021 | 47 | 2021 |
RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer S Rao, V Sigl, RA Wimmer, M Novatchkova, A Jais, G Wagner, ... Genes & Development 31 (20), 2099-2112, 2017 | 39 | 2017 |
Beneficial metabolic effects of TREM2 in obesity are uncoupled from its expression on macrophages O Sharif, JS Brunner, A Korosec, R Martins, A Jais, B Snijder, A Vogel, ... Diabetes 70 (9), 2042-2057, 2021 | 36 | 2021 |
Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity K Timper, L Paeger, C Sánchez-Lasheras, L Varela, A Jais, H Nolte, ... Cell reports 25 (2), 383-397. e10, 2018 | 32 | 2018 |