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Alexander Jais
Alexander Jais
Junior Research Group Leader, Helmholtz Institute for Metabolic, Obesity and Vascular Research
在 helmholtz-muenchen.de 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Hypothalamic inflammation in obesity and metabolic disease
A Jais, JC Brüning
The Journal of clinical investigation 127 (1), 24-32, 2017
4152017
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man
A Jais, E Einwallner, O Sharif, K Gossens, TTH Lu, SM Soyal, D Medgyesi, ...
Cell 158 (1), 25-40, 2014
3012014
Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity
A Jais, M Solas, H Backes, B Chaurasia, A Kleinridders, S Theurich, ...
Cell 165 (4), 882-895, 2016
2412016
CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity
P Hammerschmidt, D Ostkotte, H Nolte, MJ Gerl, A Jais, HL Brunner, ...
Cell 177 (6), 1536-1552. e23, 2019
2252019
Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells
CCF Homem, V Steinmann, TR Burkard, A Jais, H Esterbauer, ...
Cell 158 (4), 874-888, 2014
2162014
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ...
Nature 563 (7732), 564-568, 2018
2102018
CerS1-derived C18: 0 ceramide in skeletal muscle promotes obesity-induced insulin resistance
SM Turpin-Nolan, P Hammerschmidt, W Chen, A Jais, K Timper, ...
Cell Reports 26 (1), 1-10. e7, 2019
1422019
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
S Willenborg, DE Sanin, A Jais, X Ding, T Ulas, J Nüchel, M Popović, ...
Cell metabolism 33 (12), 2398-2414. e9, 2021
1252021
Arcuate nucleus-dependent regulation of metabolism—pathways to obesity and diabetes mellitus
A Jais, JC Brüning
Endocrine reviews 43 (2), 314-328, 2022
1172022
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
MJ Perugorria, A Esparza-Baquer, F Oakley, I Labiano, A Korosec, A Jais, ...
Gut 68 (3), 533-546, 2019
1102019
Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesion
S Tauber, A Jais, M Jeitler, S Haider, J Husa, J Lindroos, M Knöfler, ...
Molecular cancer 9, 1-16, 2010
892010
Identification of ALK in Thinness
M Orthofer, A Valsesia, R Mägi, QP Wang, J Kaczanowska, I Kozieradzki, ...
Cell 181 (6), 1246-1262. e22, 2020
872020
PNOCARC neurons promote hyperphagia and obesity upon high-fat-diet feeding
A Jais, L Paeger, T Sotelo-Hitschfeld, S Bremser, M Prinzensteiner, ...
Neuron 106 (6), 1009-1025. e10, 2020
842020
AIF-regulated oxidative phosphorylation supports lung cancer development
S Rao, L Mondragón, B Pranjic, T Hanada, G Stoll, T Köcher, P Zhang, ...
Cell research 29 (7), 579-591, 2019
752019
VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: consequences for cognitive function in humans
R Schüler, N Seebeck, MA Osterhoff, V Witte, A Flöel, A Busjahn, A Jais, ...
Molecular metabolism 11, 129-136, 2018
622018
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis
J Todoric, B Strobl, A Jais, N Boucheron, M Bayer, S Amann, J Lindroos, ...
Diabetes 60 (6), 1668-1676, 2011
562011
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity
M Porniece Kumar, AL Cremer, P Klemm, L Steuernagel, S Sundaram, ...
Nature metabolism 3 (12), 1662-1679, 2021
472021
RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer
S Rao, V Sigl, RA Wimmer, M Novatchkova, A Jais, G Wagner, ...
Genes & Development 31 (20), 2099-2112, 2017
392017
Beneficial metabolic effects of TREM2 in obesity are uncoupled from its expression on macrophages
O Sharif, JS Brunner, A Korosec, R Martins, A Jais, B Snijder, A Vogel, ...
Diabetes 70 (9), 2042-2057, 2021
362021
Mild impairment of mitochondrial OXPHOS promotes fatty acid utilization in POMC neurons and improves glucose homeostasis in obesity
K Timper, L Paeger, C Sánchez-Lasheras, L Varela, A Jais, H Nolte, ...
Cell reports 25 (2), 383-397. e10, 2018
322018
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