Quantitative real-time imaging of glutathione X Jiang, J Chen, A Bajić, C Zhang, X Song, SL Carroll, ZL Cai, M Tang, ... Nature communications 8 (1), 16087, 2017 | 229 | 2017 |
Quantitative imaging of glutathione in live cells using a reversible reaction-based ratiometric fluorescent probe X Jiang, Y Yu, J Chen, M Zhao, H Chen, X Song, AJ Matzuk, SL Carroll, ... ACS chemical biology 10 (3), 864-874, 2015 | 173 | 2015 |
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ... Nature communications 11 (1), 4268, 2020 | 141 | 2020 |
Reversible reaction-based fluorescent probe for real-time imaging of glutathione dynamics in mitochondria J Chen, X Jiang, C Zhang, KR MacKenzie, F Stossi, T Palzkill, MC Wang, ... ACS sensors 2 (9), 1257-1261, 2017 | 106 | 2017 |
Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3 X Song, J Chen, M Zhao, C Zhang, Y Yu, DM Lonard, DC Chow, T Palzkill, ... Proceedings of the National Academy of Sciences 113 (18), 4970-4975, 2016 | 86 | 2016 |
Total Synthesis of (±)‐Merrilactone A J Chen, P Gao, F Yu, Y Yang, S Zhu, H Zhai Angewandte Chemie 24 (124), 5999-6001, 2012 | 81 | 2012 |
Theoretical and experimental investigation of thermodynamics and kinetics of thiol-michael addition reactions: a case study of reversible fluorescent probes for glutathione … J Chen, X Jiang, SL Carroll, J Huang, J Wang Organic letters 17 (24), 5978-5981, 2015 | 74 | 2015 |
Total Synthesis of (−)-Jiadifenin Y Yang, X Fu, J Chen, H Zhai Angewandte Chemie International Edition 51 (39), 9825-9828, 2012 | 69 | 2012 |
Tunable thioesters as “reduction” responsive functionality for traceless reversible protein PEGylation J Chen, M Zhao, F Feng, A Sizovs, J Wang Journal of the American Chemical Society 135 (30), 10938-10941, 2013 | 64 | 2013 |
Challenges and opportunities for small-molecule fluorescent probes in redox biology applications L CarrollShaina, C WangMeng Antioxidants & Redox Signaling, 2018 | 63 | 2018 |
Steroid receptor coactivator-3 (SRC-3/AIB1) as a novel therapeutic target in triple negative breast cancer and its inhibition with a phospho-bufalin prodrug X Song, C Zhang, M Zhao, H Chen, X Liu, J Chen, DM Lonard, L Qin, J Xu, ... PloS one 10 (10), e0140011, 2015 | 39 | 2015 |
Quantitative real-time imaging of glutathione with subcellular resolution X Jiang, C Zhang, J Chen, S Choi, Y Zhou, M Zhao, X Song, X Chen, ... Antioxidants & redox signaling 30 (16), 1900-1910, 2019 | 30 | 2019 |
Precisely tunable engineering of sub-30 nm monodisperse oligonucleotide nanoparticles A Sizovs, X Song, MN Waxham, Y Jia, F Feng, J Chen, AC Wicker, J Xu, ... Journal of the American Chemical Society 136 (1), 234-240, 2014 | 30 | 2014 |
Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide J Chen, M Zhao, X Jiang, A Sizovs, MC Wang, CR Provost, J Huang, ... Analyst 141 (4), 1209-1213, 2016 | 22 | 2016 |
Development of improved SRC-3 inhibitors as breast cancer therapeutic agents L Qin, J Chen, D Lu, P Jain, Y Yu, D Cardenas, X Peng, X Yu, J Xu, ... Endocrine-related cancer 28 (10), 657-670, 2021 | 12 | 2021 |
Small molecule regulators of steroid receptor coactivators and methods of use thereof BW O'malley, DM Lonard, J Wang, J Xu, J Chen US Patent 11,253,517, 2022 | 3 | 2022 |
Fluorescent probes and mass spectrometry-based methods to quantify thiols in biological systems L Wang, F Jin, X Jiang, J Chen, MC Wang, J Wang Antioxidants & Redox Signaling 36 (4-6), 354-365, 2022 | 3 | 2022 |
Reply to ‘Pitfalls in the quantitative imaging of glutathione in living cells’ X Jiang, J Chen, J Wang Nature Communications 9 (1), 1589, 2018 | 3 | 2018 |
Probes for quantitative imaging of thiols in various environments J Wang, X Jiang, J Chen US Patent 10,921,327, 2021 | 2 | 2021 |
Glutathione quantification in live cells with real-time imaging and flow cytometry X Jiang, J Chen, MC Wang, J Wang STAR protocols 1 (3), 100170, 2020 | 2 | 2020 |