Discovery of small molecule entry inhibitors targeting the fusion peptide of SARS-CoV-2 spike protein X Hu, CZ Chen, M Xu, Z Hu, H Guo, Z Itkin, P Shinn, P Ivin, M Leek, ... ACS Medicinal Chemistry Letters 12 (8), 1267-1274, 2021 | 19 | 2021 |
SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype SB Park, M Khan, SC Chiliveri, X Hu, P Irvin, M Leek, A Grieshaber, Z Hu, ... Communications biology 6 (1), 556, 2023 | 14 | 2023 |
Targeting the fusion process of SARS-CoV-2 infection by small molecule inhibitors SB Park, P Irvin, Z Hu, M Khan, X Hu, Q Zeng, C Chen, M Xu, M Leek, ... MBio 13 (1), e03238-21, 2022 | 11 | 2022 |
Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion CD Ma, M Imamura, DC Talley, A Rolt, X Xu, AQ Wang, D Le, T Uchida, ... Nature microbiology 5 (12), 1532-1541, 2020 | 10 | 2020 |
Discovery and optimization of a 4-aminopiperidine scaffold for inhibition of hepatitis C virus assembly A Rolt, DC Talley, SB Park, Z Hu, A Dulcey, C Ma, P Irvin, M Leek, ... Journal of medicinal chemistry 64 (13), 9431-9443, 2021 | 4 | 2021 |