Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients K Ishii, M Pouzolles, CD Chien, RA Erwin-Cohen, ME Kohler, H Qin, H Lei, ... The Journal of clinical investigation 130 (10), 5425-5443, 2020 | 55 | 2020 |
Impact of HLA‐mismatch in unrelated donor hematopoietic stem cell transplantation: a meta‐analysis N Kekre, KS Mak, KH Stopsack, M Binder, K Ishii, E Brånvall, CS Cutler American Journal of Hematology 91 (6), 551-555, 2016 | 50 | 2016 |
Preclinical development of FLT3-redirected chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia CD Chien, CT Sauter, K Ishii, SM Nguyen, F Shen, SK Tasian, W Chen, ... Blood, The Journal of the American Society of Hematology 128 (22), 1072-1072, 2016 | 39 | 2016 |
Applying a clinical lens to animal models of CAR-T cell therapies BB Duncan, CE Dunbar, K Ishii Molecular Therapy-Methods & Clinical Development 27, 17-31, 2022 | 35 | 2022 |
Tocilizumab-refractory cytokine release syndrome (CRS) triggered by chimeric antigen receptor (CAR)-transduced T cells may have distinct cytokine profiles compared to typical CRS K Ishii, H Shalabi, B Yates, C Delbrook, CL Mackall, TJ Fry, NN Shah Blood 128 (22), 3358, 2016 | 29 | 2016 |
Murine pre–B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor H Qin, K Ishii, S Nguyen, PP Su, CR Burk, BH Kim, BB Duncan, S Tarun, ... Blood, The Journal of the American Society of Hematology 132 (18), 1899-1910, 2018 | 25 | 2018 |
Novel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic) K Ishii, AJ Barrett Therapeutic Advances in Hematology 7 (1), 17-39, 2016 | 22 | 2016 |
Anemia of central origin K Ishii, NS Young Seminars in hematology 52 (4), 321-338, 2015 | 15 | 2015 |
Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas GOS Coyne, S Kummar, RS Meehan, K Do, JM Collins, L Anderson, ... Oncotarget 11 (44), 3959, 2020 | 9 | 2020 |
Murine allogeneic CAR T cells integrated before or early after posttransplant cyclophosphamide exert antitumor effects MT Patterson, SM Khan, NS Nunes, RE Fletcher, J Bian, AD Hadjis, ... Blood 141 (6), 659-672, 2023 | 6 | 2023 |
A prospective analysis of blood donation history and risk of non-Hodgkin lymphoma K Ishii, BM Birmann, X Zhang, E Giovannucci, KA Bertrand Leukemia & lymphoma 57 (6), 1423-1428, 2016 | 6 | 2016 |
Multi-tiered approach to detect autoimmune cross-reactivity of therapeutic T cell receptors K Ishii, JS Davies, AL Sinkoe, KA Nguyen, SM Norberg, CP McIntosh, ... Science Advances 9 (30), eadg9845, 2023 | 5 | 2023 |
A phase 1 trial of TRC102 (methoxyamine HCl) with temozolomide (TMZ) in patients with solid tumors and lymphomas. RS Meehan, AP Chen, GH O'Sullivan Coyne, JM Collins, S Kummar, ... Journal of Clinical Oncology 34 (15_suppl), 2556-2556, 2016 | 4 | 2016 |
FLT3 chimeric antigen receptor T cell therapy induces B to T cell lineage switch in infant acute lymphoblastic leukemia CD Chien, L Yang, SM Nguyen, CT Sauter, K Ishii, F Shen, SK Tasian, ... Cancer Research 78 (13_Supplement), 1630-1630, 2018 | 2 | 2018 |
α-fetoprotein secreting extrapulmonary small-cell carcinoma of the liver MA Walshauser, K Ishii, K Murugappan, S Masoom, S Yong, ... Journal of Clinical Oncology 31 (10), e152-e154, 2013 | 2 | 2013 |
Perforin Is Dispensable for Anti-CD19 CAR-T Cell Cytotoxicity but Contributes to CAR-T Cell Contraction and Regulates Host Inflammatory Response K Ishii, CD Chien, R Erwin-Cohen, HA Young, TJ Fry Blood 130, 1918, 2017 | 1 | 2017 |
Hla class i-restricted t cell receptors against cd22 K Ishii, C Hinrichs US Patent App. 18/277,521, 2024 | | 2024 |
CD22 TCR-Engineered T Cells Exert Anti-Leukemia Cytotoxicity without Causing Inflammatory Responses K Ishii, Z Liu, JS Davies, KA Nguyen, CP McIntosh, T Kadakia, ... Blood 142, 2085, 2023 | | 2023 |
Hla class i-restricted t cell receptors against cd20 K Ishii, CS Hinrichs US Patent App. 18/012,056, 2023 | | 2023 |
The 1000 mouse experiment: quantifying the variability of tumor response to CAR T cell therapy A Kenet, S Achar, M Pouzolles, A Su, T Kondo, A Dwivedi, H Qin, C Chien, ... The Journal of Immunology 210 (1_Supplement), 142.01-142.01, 2023 | | 2023 |