| Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme WJ Thompson, WL Terasaki, PM Epstein, SJ Strada Adv Cyclic Nucleotide Res 10, 69-92, 1979 | 484 | 1979 |
| Local anesthetics, mepacrine, and propranolol are antagonists of calmodulin. M Volpi, RI Sha'Afi, PM Epstein, DM Andrenyak, MB Feinstein Proceedings of the National Academy of Sciences 78 (2), 795-799, 1981 | 237 | 1981 |
| Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin PM Epstein, K Fiss, R Hachisu, DM Andrenyak Biochemical and biophysical research communications 105 (3), 1142-1149, 1982 | 184 | 1982 |
| Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies A Lerner, PM Epstein Biochemical Journal 393 (1), 21-41, 2006 | 155 | 2006 |
| Expression of cGMP-specific phosphodiesterase 9A mRNA in the rat brain SG Andreeva, P Dikkes, PM Epstein, PA Rosenberg Journal of Neuroscience 21 (22), 9068-9076, 2001 | 146 | 2001 |
| Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells. X Jiang, J Li, M Paskind, PM Epstein Proceedings of the National Academy of Sciences 93 (20), 11236-11241, 1996 | 131 | 1996 |
| The effect of dexamethasone on parathyroid hormone stimulation of adenylate cyclase in ROS 17/2.8 cells SB RODAN, MK FISCHER, JJ EGAN, PM EPSTEIN, GA RODAN Endocrinology 115 (3), 951-958, 1984 | 106 | 1984 |
| Purification and characterization of high-affinity cyclic adenosine monophosphate phosphodiesterase from dog kidney WJ Thompson, PM Epstein, SJ Strada Biochemistry 18 (23), 5228-5237, 1979 | 104 | 1979 |
| A novel cyclic GMP stimulated phosphodiesterase from rat brain Q Yang, M Paskind, G Bolger, WJ Thompson, DR Repaske, LS Cutler, ... Biochemical and biophysical research communications 205 (3), 1850-1858, 1994 | 94 | 1994 |
| Phosphodiesterase 8 (PDE8) regulates chemotaxis of activated lymphocytes H Dong, V Osmanova, PM Epstein, S Brocke Biochemical and biophysical research communications 345 (2), 713-719, 2006 | 89 | 2006 |
| Inhibition of breast cancer cell migration by activation of cAMP signaling H Dong, KP Claffey, S Brocke, PM Epstein Breast cancer research and treatment 152, 17-28, 2015 | 82 | 2015 |
| PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER AG Vang, SZ Ben-Sasson, H Dong, B Kream, MP DeNinno, MM Claffey, ... PloS one 5 (8), e12011, 2010 | 82 | 2010 |
| Cyclic nucleotide phosphodiesterase in normal and leukemic human lymphocytes and lymphoblasts PM Epstein, R Hachisu Advances in cyclic nucleotide and protein phosphorylation research 16, 303-324, 1984 | 81 | 1984 |
| Antisense oligodeoxynucleotide against phosphodiesterase PM Epstein US Patent 5,885,834, 1999 | 78 | 1999 |
| Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells H Dong, C Zitt, C Auriga, A Hatzelmann, PM Epstein Biochemical pharmacology 79 (3), 321-329, 2010 | 62 | 2010 |
| Cyclic nucleotide metabolism coupled to cytodifferentiation of Blastocladiella emersonii. PM Silverman, PM Epstein Proceedings of the National Academy of Sciences 72 (2), 442-446, 1975 | 62 | 1975 |
| Muscarinic antagonism of the effects of phosphodiesterase inhibitor (methylisobutylxanthine) in embryonic chick ventricle. RL Biegon, PM Epstein, AJ Pappano Journal of Pharmacology and Experimental Therapeutics 215 (2), 348-356, 1980 | 59 | 1980 |
| Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl … S Tiwari, H Dong, EJ Kim, L Weintraub, PM Epstein, A Lerner Biochemical pharmacology 69 (3), 473-483, 2005 | 57 | 2005 |
| Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells PM Epstein, JS Mills, CP Ross, SJ Strada, EM Hersh, WJ Thompson Cancer Research 37 (11), 4016-4023, 1977 | 53 | 1977 |
| Catalytic and kinetic properties of purified high-affinity cyclic AMP phosphodiesterase from dog kidney PM Epstein, SJ Strada, K Sarada, WJ Thompson Archives of Biochemistry and Biophysics 218 (1), 119-133, 1982 | 52 | 1982 |
