Isogenic human iPSC Parkinson’s model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription SD Ryan, N Dolatabadi, SF Chan, X Zhang, MW Akhtar, J Parker, ... Cell 155 (6), 1351-1364, 2013 | 485 | 2013 |
Randomised controlled trial of a synthetic triglyceride milk formula for preterm infants A Lucas, P Quinlan, S Abrams, S Ryan, S Meah, PJ Lucas Archives of Disease in Childhood-Fetal and Neonatal Edition 77 (3), F178-F184, 1997 | 189 | 1997 |
Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein T Ryan, VV Bamm, MG Stykel, CL Coackley, KM Humphries, ... Nature communications 9 (1), 817, 2018 | 188 | 2018 |
Derivation of enriched oligodendrocyte cultures and oligodendrocyte/neuron myelinating co-cultures from post-natal murine tissues RW O'Meara, SD Ryan, H Colognato, R Kothary JoVE (Journal of Visualized Experiments), e3324, 2011 | 113 | 2011 |
Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative β-catenin KAM Kennedy, T Porter, V Mehta, SD Ryan, F Price, V Peshdary, ... BMC biology 7, 1-21, 2009 | 110 | 2009 |
Amyloid-β42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism SD Ryan, SN Whitehead, LA Swayne, TC Moffat, W Hou, M Ethier, ... Proceedings of the National Academy of Sciences 106 (49), 20936-20941, 2009 | 98 | 2009 |
NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism S Tu, MW Akhtar, RM Escorihuela, A Amador-Arjona, V Swarup, J Parker, ... Nature communications 8 (1), 1488, 2017 | 89 | 2017 |
Microtubule stability, Golgi organization, and transport flux require dystonin-a2–MAP1B interaction SD Ryan, K Bhanot, A Ferrier, Y De Repentigny, A Chu, A Blais, ... Journal of Cell Biology 196 (6), 727-742, 2012 | 72 | 2012 |
Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I α2 catalytic subunit F Bonin, SD Ryan, L Migahed, F Mo, J Lallier, DJ Franks, H Arai, ... Journal of Biological Chemistry 279 (50), 52425-52436, 2004 | 57 | 2004 |
Nitration of microtubules blocks axonal mitochondrial transport in a human pluripotent stem cell model of Parkinson's disease MG Stykel, K Humphries, MP Kirby, C Czaniecki, T Wang, T Ryan, ... The FASEB Journal 32 (10), 5350-5364, 2018 | 56 | 2018 |
Platelet activating factor‐induced neuronal apoptosis is initiated independently of its G‐protein coupled PAF receptor and is inhibited by the benzoate orsellinic acid SD Ryan, CS Harris, F Mo, H Lee, ST Hou, NG Bazan, PS Haddad, ... Journal of neurochemistry 103 (1), 88-97, 2007 | 53 | 2007 |
Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro-or anti-apoptotic signaling in primary neuronss⃞ SD Ryan, CS Harris, CL Carswell, JE Baenziger, SAL Bennett Journal of lipid research 49 (10), 2250-2258, 2008 | 44 | 2008 |
Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function SD Ryan, A Ferrier, T Sato, RW O'Meara, Y De Repentigny, SX Jiang, ... Molecular biology of the cell 23 (4), 553-566, 2012 | 38 | 2012 |
High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons JC Piña-Crespo, M Talantova, EG Cho, W Soussou, N Dolatabadi, ... Journal of Neuroscience 32 (45), 15837-15842, 2012 | 37 | 2012 |
α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology MG Stykel, KM Humphries, E Kamski-Hennekam, B Buchner-Duby, ... Cell Reports 35 (6), 2021 | 36 | 2021 |
Axonal pathology in hPSC-based models of Parkinson’s disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus C Czaniecki, T Ryan, MG Stykel, J Drolet, J Heide, R Hallam, S Wood, ... Proceedings of the National Academy of Sciences 116 (28), 14280-14289, 2019 | 35 | 2019 |
Nitrosative stress in Parkinson’s disease MG Stykel, SD Ryan npj Parkinson's Disease 8 (1), 104, 2022 | 34 | 2022 |
Nitric oxide: a regulator of cellular function in health and disease L Sobrevia, L Ooi, S Ryan, JR Steinert Oxidative medicine and cellular longevity 2016, 2016 | 31 | 2016 |
Biochemical and cellular analysis of human variants of the DYT 1 dystonia protein, TorsinA/TOR1A J Hettich, SD Ryan, ON de Souza, LF Saraiva Macedo Timmers, S Tsai, ... Human mutation 35 (9), 1101-1113, 2014 | 30 | 2014 |
Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction NA Atai, SD Ryan, R Kothary, XO Breakefield, FC Nery International journal of cell biology 2012 (1), 634214, 2012 | 30 | 2012 |