Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer Y Xie, Y Zhao, L Shi, W Li, K Chen, M Li, X Chen, H Zhang, T Li, ... The Journal of clinical investigation 130 (4), 2111-2128, 2020 | 144 | 2020 |
MLKL and FADD are critical for suppressing progressive lymphoproliferative disease and activating the NLRP3 inflammasome X Zhang, C Fan, H Zhang, Q Zhao, Y Liu, C Xu, Q Xie, X Wu, X Yu, ... Cell reports 16 (12), 3247-3259, 2016 | 90 | 2016 |
Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis X Zhang, H Zhang, C Xu, X Li, M Li, X Wu, W Pu, B Zhou, H Wang, D Li, ... Nature communications 10 (1), 4158, 2019 | 87 | 2019 |
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis R Miao, C Jiang, WY Chang, H Zhang, J An, F Ho, P Chen, H Zhang, ... Immunity 56 (11), 2523-2541. e8, 2023 | 79 | 2023 |
Control of leaf senescence by an MeOH-jasmonates cascade that is epigenetically regulated by OsSRT1 in rice CY Fang, H Zhang, J Wan, YY Wu, K Li, C Jin, W Chen, SC Wang, ... Molecular Plant 9 (10), 1366-1378, 2016 | 77 | 2016 |
The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells S Sen Santara, DJ Lee, Â Crespo, JJ Hu, C Walker, X Ma, Y Zhang, ... Nature 616 (7956), 348-356, 2023 | 68 | 2023 |
RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice Y Liu, C Fan, Y Zhang, X Yu, X Wu, X Zhang, Q Zhao, H Zhang, Q Xie, ... Cell Death & Differentiation 24 (8), 1459-1469, 2017 | 49 | 2017 |
Catalytically inactive RIP1 and RIP3 deficiency protect against acute ischemic stroke by inhibiting necroptosis and neuroinflammation Y Zhang, M Li, X Li, H Zhang, L Wang, X Wu, H Zhang, Y Luo Cell Death & Disease 11 (7), 565, 2020 | 48 | 2020 |
RIPK3 mediates necroptosis during embryonic development and postnatal inflammation in Fadd-deficient mice Q Zhao, XJ Yu, HW Zhang, YB Liu, XX Zhang, XX Wu, Q Xie, M Li, H Ying, ... Cell reports 19 (4), 798-808, 2017 | 45 | 2017 |
Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia X Li, F Li, X Zhang, H Zhang, Q Zhao, M Li, X Wu, L Wang, J Liu, X Wu, ... Cell Death & Differentiation 29 (8), 1500-1512, 2022 | 30 | 2022 |
Crucial roles of the RIP homotypic interaction motifs of RIPK3 in RIPK1-dependent cell death and lymphoproliferative disease H Zhang, X Wu, X Li, M Li, F Li, L Wang, X Zhang, Y Zhang, Y Luo, ... Cell Reports 31 (7), 2020 | 18 | 2020 |
Gambogenic acid inhibits LPS-simulated inflammatory response by suppressing NF-κB and MAPK in macrophages X Yu, Q Zhao, H Zhang, C Fan, X Zhang, Q Xie, C Xu, Y Liu, X Wu, Q Han, ... Acta Biochim Biophys Sin 48 (5), 454-461, 2016 | 17 | 2016 |
RIPK3/Fas-associated death domain axis regulates pulmonary immunopathology to cryptococcal infection independent of necroptosis Z Fa, Q Xie, W Fang, H Zhang, H Zhang, J Xu, W Pan, J Xu, MA Olszewski, ... Frontiers in Immunology 8, 1055, 2017 | 13 | 2017 |
Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development M Li, Y Liu, C Xu, Q Zhao, J Liu, M Xing, X Li, H Zhang, X Wu, L Wang, ... Cell Death & Differentiation 29 (10), 2034-2045, 2022 | 11 | 2022 |
A novel sgRNA selection system for CRISPR-Cas9 in mammalian cells H Zhang, X Zhang, C Fan, Q Xie, C Xu, Q Zhao, Y Liu, X Wu, H Zhang Biochemical and biophysical research communications 471 (4), 528-532, 2016 | 10 | 2016 |
Develop an efficient and specific AAV-based labeling system for Muller glia in mice Y Gao, K Fang, Z Yan, H Zhang, G Geng, W Wu, D Xu, H Zhang, N Zhong, ... Scientific reports 12 (1), 22410, 2022 | 9 | 2022 |
Treatment of autosomal dominant retinitis pigmentosa caused by RHO-P23H mutation with high-fidelity Cas13X in mice Z Yan, Y Yao, L Li, L Cai, H Zhang, S Zhang, Q Xiao, X Wang, E Zuo, C Xu, ... Molecular Therapy-Nucleic Acids 33, 750-761, 2023 | 8 | 2023 |
Caspase-8 Blocks Receptor-Interacting Protein Kinase-1 Kinase–Independent Necroptosis during Embryogenesis H Zhang, X Wu, M Li, X Li, L Wang, J Liu, Y Ou, X Wu, M Xing, F Li, ... ImmunoHorizons 6 (7), 465-475, 2022 | 1 | 2022 |
Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity P Fontana, G Du, Y Zhang, H Zhang, SM Vora, JJ Hu, M Shi, AB Tufan, ... Cell, 2024 | | 2024 |
Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation Y Zhang, P Naderi Yeganeh, H Zhang, SY Wang, Z Li, B Gu, DJ Lee, ... Nature Immunology, 1-13, 2024 | | 2024 |