Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae BR O'Keefe, B Giomarelli, DL Barnard, SR Shenoy, PKS Chan, ... Journal of virology 84 (5), 2511-2521, 2010 | 360 | 2010 |
Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component BR O'Keefe, F Vojdani, V Buffa, RJ Shattock, DC Montefiori, J Bakke, ... Proceedings of the National Academy of Sciences 106 (15), 6099-6104, 2009 | 331 | 2009 |
Production of pharmaceutical‐grade recombinant aprotinin and a monoclonal antibody product using plant‐based transient expression systems GP Pogue, F Vojdani, KE Palmer, E Hiatt, S Hume, J Phelps, L Long, ... Plant biotechnology journal 8 (5), 638-654, 2010 | 257 | 2010 |
The molecular biology of mastreviruses KE Palmer, EP Rybicki Advances in virus research 50, 183-234, 1998 | 248 | 1998 |
Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications ML Smith, JA Lindbo, S Dillard-Telm, PM Brosio, AB Lasnik, ... Virology 348 (2), 475-488, 2006 | 224 | 2006 |
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 193 | 2021 |
Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding NE Ziółkowska, BR O'Keefe, T Mori, C Zhu, B Giomarelli, F Vojdani, ... Structure 14 (7), 1127-1135, 2006 | 191 | 2006 |
Griffithsin has antiviral activity against hepatitis C virus P Meuleman, A Albecka, S Belouzard, K Vercauteren, L Verhoye, ... Antimicrobial agents and chemotherapy 55 (11), 5159-5167, 2011 | 186 | 2011 |
Rapid detection of SARS-CoV-2 antibodies using electrochemical impedance-based detector MZ Rashed, JA Kopechek, MC Priddy, KT Hamorsky, KE Palmer, N Mittal, ... Biosensors and Bioelectronics 171, 112709, 2021 | 173 | 2021 |
Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti‐HIV microbicide P Emau, B Tian, BR O’keefe, T Mori, JB McMahon, KE Palmer, Y Jiang, ... Journal of medical primatology 36 (4‐5), 244-253, 2007 | 157 | 2007 |
Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin JK Millet, K Séron, RN Labitt, A Danneels, KE Palmer, GR Whittaker, ... Antiviral research 133, 1-8, 2016 | 143 | 2016 |
Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models C Barton, JC Kouokam, AB Lasnik, O Foreman, A Cambon, G Brock, ... Antimicrobial agents and chemotherapy 58 (1), 120-127, 2014 | 140 | 2014 |
Griffithsin protects mice from genital herpes by preventing cell-to-cell spread B Nixon, M Stefanidou, PMM Mesquita, E Fakioglu, T Segarra, L Rohan, ... Journal of virology 87 (11), 6257-6269, 2013 | 139 | 2013 |
Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate JC Kouokam, D Huskens, D Schols, A Johannemann, SK Riedell, ... Plos one 6 (8), e22635, 2011 | 139 | 2011 |
Geminivirus vectors for high‐level expression of foreign proteins in plant cells TS Mor, YS Moon, KE Palmer, HS Mason Biotechnology and bioengineering 81 (4), 430-437, 2003 | 139 | 2003 |
Perspective: edible vaccines—a concept coming of age TS Mor, MA Gómez-Lim, KE Palmer Trends in Microbiology 6 (11), 449-453, 1998 | 128 | 1998 |
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12 Y Teng, F Xu, X Zhang, J Mu, M Sayed, X Hu, C Lei, M Sriwastva, ... Molecular Therapy 29 (8), 2424-2440, 2021 | 127 | 2021 |
Protection of rabbits against cutaneous papillomavirus infection using recombinant tobacco mosaic virus containing L2 capsid epitopes KE Palmer, A Benko, SA Doucette, TI Cameron, T Foster, KM Hanley, ... Vaccine 24 (26), 5516-5525, 2006 | 106 | 2006 |
Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses LC Nguyen, D Yang, V Nicolaescu, TJ Best, H Gula, D Saxena, ... Science Advances 8 (8), eabi6110, 2022 | 102 | 2022 |
TMV-peptide fusion vaccines induce cell-mediated immune responses and tumor protection in two murine models AA McCormick, TA Corbo, S Wykoff-Clary, LV Nguyen, ML Smith, ... Vaccine 24 (40-41), 6414-6423, 2006 | 102 | 2006 |