An ATR-and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage TP Heffernan, DA Simpson, AR Frank, AN Heinloth, RS Paules, ... Molecular and cellular biology 22 (24), 8552-8561, 2002 | 310 | 2002 |
Genetic determinants of cellular addiction to DNA polymerase theta W Feng, DA Simpson, J Carvajal-Garcia, BA Price, RJ Kumar, LE Mose, ... Nature communications 10 (1), 4286, 2019 | 146 | 2019 |
Caffeine and human DNA metabolism: the magic and the mystery WK Kaufmann, TP Heffernan, LM Beaulieu, S Doherty, AR Frank, Y Zhou, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 532 (1 …, 2003 | 123 | 2003 |
Deduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypes KL McKnight, DA Simpson, SC Lin, TA Knott, JM Polo, DF Pence, ... Journal of virology 70 (3), 1981-1989, 1996 | 110 | 1996 |
Topoisomerase IIα maintains genomic stability through decatenation G2 checkpoint signaling JJ Bower, GF Karaca, Y Zhou, DA Simpson, M Cordeiro-Stone, ... Oncogene 29 (34), 4787-4799, 2010 | 102 | 2010 |
Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression WK Kaufmann, KR Nevis, P Qu, JG Ibrahim, T Zhou, Y Zhou, DA Simpson, ... Journal of Investigative Dermatology 128 (1), 175-187, 2008 | 89 | 2008 |
Sindbis-group alphavirus replication in periosteum and endosteum of long bones in adult mice MT Heise, DA Simpson, RE Johnston Journal of Virology 74 (19), 9294-9299, 2000 | 89 | 2000 |
Cell cycle checkpoint function in bladder cancer SC Doherty, SR McKeown, V McKelvey-Martin, CS Downes, A Atala, ... Journal of the National Cancer Institute 95 (24), 1859-1868, 2003 | 88 | 2003 |
Cdc7-Dbf4 and the human S checkpoint response to UVC TP Heffernan, K Unsal-Kacmaz, AN Heinloth, DA Simpson, RS Paules, ... Journal of Biological Chemistry 282 (13), 9458-9468, 2007 | 86 | 2007 |
Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells JJ Bower, LD Vance, M Psioda, SL Smith-Roe, DA Simpson, JG Ibrahim, ... NPJ breast cancer 3 (1), 9, 2017 | 82 | 2017 |
Profiles of Global Gene Expression in Ionizing-Radiation–Damaged Human Diploid Fibroblasts Reveal Synchronization behind the G1 Checkpoint in a G0-like … T Zhou, JW Chou, DA Simpson, Y Zhou, TE Mullen, M Medeiros, ... Environmental health perspectives 114 (4), 553-559, 2006 | 82 | 2006 |
Complete nucleotide sequence and full-length cDNA clone of SA AR86, a South African alphavirus related to Sindbis DA Simpson, NL Davis, SC Lin, D Russell, RE Johnston Virology 222 (2), 464-469, 1996 | 72 | 1996 |
Prognostic factors related to survival and groin recurrence following therapeutic lymph node dissection for lower limb malignant melanoma MW Kissin, DA Simpson, D Easton, H White, G Westbury British journal of surgery 74 (11), 1023-1026, 1987 | 65 | 1987 |
A single amino acid change in nsP1 attenuates neurovirulence of the Sindbis-group alphavirus SA AR86 MT Heise, DA Simpson, RE Johnston Journal of Virology 74 (9), 4207-4213, 2000 | 62 | 2000 |
The Epstein-Barr Virus Immediate-Early Protein BZLF1 Induces both a G2 and a Mitotic Block A Mauser, E Holley-Guthrie, D Simpson, W Kaufmann, S Kenney Journal of virology 76 (19), 10030-10037, 2002 | 58 | 2002 |
An attenuating mutation in nsP1 of the Sindbis-group virus SA AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis MT Heise, LJ White, DA Simpson, C Leonard, KA Bernard, RB Meeker, ... Journal of virology 77 (2), 1149-1156, 2003 | 57 | 2003 |
SWI/SNF complexes are required for full activation of the DNA-damage response SL Smith-Roe, J Nakamura, D Holley, PD Chastain, GB Rosson, ... Oncotarget 6 (2), 732, 2015 | 55 | 2015 |
p53-Dependent but ATM-independent inhibition of DNA synthesis and G2 arrest in cadmium-treated human fibroblasts F Cao, T Zhou, D Simpson, Y Zhou, J Boyer, B Chen, T Jin, ... Toxicology and applied pharmacology 218 (2), 174-185, 2007 | 46 | 2007 |
Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score British journal of surgery 108 (11), 1274-1292, 2021 | 45 | 2021 |
Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts NM King, N Nikolaishvili-Feinberg, MF Bryant, DD Luche, TP Heffernan, ... DNA repair 4 (6), 714-724, 2005 | 42 | 2005 |