Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation M Muik, I Frischauf, I Derler, M Fahrner, J Bergsmann, P Eder, R Schindl, ... Journal of Biological Chemistry 283 (12), 8014-8022, 2008 | 500 | 2008 |
A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels M Muik, M Fahrner, I Derler, R Schindl, J Bergsmann, I Frischauf, ... Journal of biological chemistry 284 (13), 8421-8426, 2009 | 398 | 2009 |
Coassembly of Trp1 and Trp3 proteins generates diacylglycerol-and Ca2+-sensitive cation channels B Lintschinger, M Balzer-Geldsetzer, T Baskaran, WF Graier, C Romanin, ... Journal of Biological Chemistry 275 (36), 27799-27805, 2000 | 355 | 2000 |
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ... The EMBO journal 30 (9), 1678-1689, 2011 | 283 | 2011 |
TRPC3 and TRPC4 associate to form a redox-sensitive cation channel: evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells M Poteser, A Graziani, C Rosker, P Eder, I Derler, H Kahr, MX Zhu, ... Journal of Biological Chemistry 281 (19), 13588-13595, 2006 | 245 | 2006 |
Ca2+ signaling by TRPC3 involves Na+ entry and local coupling to the Na+/Ca2+ exchanger C Rosker, A Graziani, M Lukas, P Eder, MX Zhu, C Romanin, K Groschner Journal of Biological Chemistry 279 (14), 13696-13704, 2004 | 217 | 2004 |
Novel pyrazole compounds for pharmacological discrimination between receptor‐operated and store‐operated Ca2+ entry pathways H Schleifer, B Doleschal, M Lichtenegger, R Oppenrieder, I Derler, ... British journal of pharmacology 167 (8), 1712-1722, 2012 | 204 | 2012 |
Trp proteins form store-operated cation channels in human vascular endothelial cells K Groschner, S Hingel, B Lintschinger, M Balzer, C Romanin, X Zhu, ... FEBS letters 437 (1-2), 101-106, 1998 | 204 | 1998 |
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1–3 channels by a STIM1 coiled-coil mutant I Frischauf, M Muik, I Derler, J Bergsmann, M Fahrner, R Schindl, ... Journal of biological chemistry 284 (32), 21696-21706, 2009 | 198 | 2009 |
Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel: heteromeric assembly of TRPC1-TRPC3 X Liu, BC Bandyopadhyay, BB Singh, K Groschner, IS Ambudkar Journal of Biological Chemistry 280 (22), 21600-21606, 2005 | 190 | 2005 |
Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line C Li, S Rezania, S Kammerer, A Sokolowski, T Devaney, A Gorischek, ... Scientific reports 5 (1), 8364, 2015 | 185 | 2015 |
Evidence for a role of Trp proteins in the oxidative stress-induced membrane conductances of porcine aortic endothelial cells M Balzer, B Lintschinger, K Groschner Cardiovascular research 42 (2), 543-549, 1999 | 181 | 1999 |
2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size R Schindl, J Bergsmann, I Frischauf, I Derler, M Fahrner, M Muik, R Fritsch, ... Journal of Biological Chemistry 283 (29), 20261-20267, 2008 | 166 | 2008 |
A Ca2+ Release-activated Ca2+ (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels*♦ I Derler, M Fahrner, M Muik, B Lackner, R Schindl, K Groschner, ... Journal of biological chemistry 284 (37), 24933-24938, 2009 | 162 | 2009 |
Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo H Bischof, M Rehberg, S Stryeck, K Artinger, E Eroglu, ... Nature Communications 8 (1), 1422, 2017 | 157 | 2017 |
The Extended Transmembrane Orai1 N-Terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1*♦ I Derler, P Plenk, M Fahrner, M Muik, I Jardin, R Schindl, HJ Gruber, ... Journal of Biological Chemistry 288 (40), 29025-29034, 2013 | 152 | 2013 |
Functional consequences of P/Q-type Ca2+ channel Cav2. 1 missense mutations associated with episodic ataxia type 2 and progressive ataxia E Wappl, A Koschak, M Poteser, MJ Sinnegger, D Walter, A Eberhart, ... Journal of Biological Chemistry 277 (9), 6960-6966, 2002 | 130 | 2002 |
Na+/Ca2+ exchange facilitates Ca2+-dependent activation of endothelial nitric-oxide synthase M Teubl, K Groschner, SD Kohlwein, B Mayer, K Schmidt Journal of Biological Chemistry 274 (41), 29529-29535, 1999 | 126 | 1999 |
Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+‐dependent inactivation I Derler, M Hofbauer, H Kahr, R Fritsch, M Muik, K Kepplinger, ME Hack, ... The Journal of physiology 577 (1), 31-44, 2006 | 124 | 2006 |
Current modulation and membrane targeting of the calcium channel α1C subunit are independent functions of the β subunit U Gerster, B Neuhuber, K Groschner, J Striessnig, BE Flucher The Journal of physiology 517 (2), 353-368, 1999 | 124 | 1999 |