Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment L Chen, T Yang, DW Lu, H Zhao, YL Feng, H Chen, DQ Chen, ND Vaziri, ... Biomedicine & Pharmacotherapy 101, 670-681, 2018 | 322 | 2018 |
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan DQ Chen, G Cao, H Chen, CP Argyopoulos, H Yu, W Su, L Chen, ... Nature communications 10 (1), 1476, 2019 | 210 | 2019 |
Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine M Wang, L Chen, D Liu, H Chen, DD Tang, YY Zhao Chemico-Biological Interactions 273, 133-141, 2017 | 181 | 2017 |
Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-β signaling X Yan, Z Lin, F Chen, X Zhao, H Chen, Y Ning, YG Chen Journal of Biological Chemistry 284 (44), 30097-30104, 2009 | 166 | 2009 |
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination T Fei, K Xia, Z Li, B Zhou, S Zhu, H Chen, J Zhang, Z Chen, H Xiao, ... Genome research 20 (1), 36-44, 2010 | 165 | 2010 |
Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic … DQ Chen, G Cao, H Chen, D Liu, W Su, XY Yu, ND Vaziri, XH Liu, X Bai, ... Redox biology 12, 505-521, 2017 | 163 | 2017 |
Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression H Chen, G Cao, DQ Chen, M Wang, ND Vaziri, ZH Zhang, JR Mao, X Bai, ... Redox Biology 10, 168-178, 2016 | 161 | 2016 |
Traditional uses, phytochemistry, pharmacology, toxicology and quality control of Alisma orientale (Sam.) Juzep: A review YYZ Ting Tian, Hua Chen Journal of Ethnopharmacology 158, 373-387, 2014 | 154 | 2014 |
Traditional uses, fermentation, phytochemistry and pharmacology of Phellinus linteus: A review H Chen, T Tian, H Miao, YY Zhao Fitoterapia 113, 6-26, 2016 | 147 | 2016 |
Metagenomic profiling of the pro-inflammatory gut microbiota in ankylosing spondylitis C Zhou, H Zhao, X Xiao, R Guo, Q Wang, H Chen, L Zhao, C Zhang, ... Journal of autoimmunity 107, 102360, 2020 | 131 | 2020 |
Combined clinical phenotype and lipidomic analysis reveals the impact of chronic kidney disease on lipid metabolism H Chen, L Chen, D Liu, DQ Chen, ND Vaziri, XY Yu, L Zhang, W Su, X Bai, ... Journal of proteome research 16 (4), 1566-1578, 2017 | 119 | 2017 |
Lipidomics Biomarkers of Diet-Induced Hyperlipidemia and Its Treatment with Poria cocos H Miao, YH Zhao, ND Vaziri, DD Tang, H Chen, H Chen, M Khazaeli, ... Journal of agricultural and food chemistry 64 (4), 969-979, 2016 | 117 | 2016 |
Diuretic activity of some fractions of the epidermis of Poria cocos RCL Ya-Long Feng, Ping Lei, Hua Chen, Ting Tian, Lu Yin, Dan-Qian Chen ... Journal of Ethnopharmacology 150 (3), 1114-1118, 2013 | 108 | 2013 |
The link between phenotype and fatty acid metabolism in advanced chronic kidney disease DQ Chen, H Chen, L Chen, ND Vaziri, M Wang, XR Li, YY Zhao Nephrology Dialysis Transplantation 32 (7), 1154-1166, 2017 | 106 | 2017 |
Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis L Chen, DQ Chen, JR Liu, J Zhang, ND Vaziri, S Zhuang, H Chen, ... Experimental & molecular medicine 51 (3), 1-18, 2019 | 100 | 2019 |
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy L Chen, DQ Chen, M Wang, D Liu, H Chen, F Dou, ND Vaziri, YY Zhao Chemico-Biological Interactions 273, 56-72, 2017 | 99 | 2017 |
Plasma lipidomics reveal profound perturbation of glycerophospholipids, fatty acids, and sphingolipids in diet-induced hyperlipidemia YYZ Hua Miao, Hua Chen, Song-Wen Pei, Xu Bai, Nosratola D. Vaziri Chemico-Biological Interactions 228, 79-87, 2015 | 99 | 2015 |
Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 … H Chen, T Yang, MC Wang, DQ Chen, Y Yang, YY Zhao Phytomedicine 42, 207-218, 2018 | 96 | 2018 |
Poricoic acid ZA, a novel RAS inhibitor, attenuates tubulo-interstitial fibrosis and podocyte injury by inhibiting TGF-β/Smad signaling pathway M Wang, DQ Chen, MC Wang, H Chen, L Chen, D Liu, H Zhao, YY Zhao Phytomedicine 36, 243-253, 2017 | 95 | 2017 |
Metabolomics in dyslipidemia RCL Hua Chen, Hua Miao, Ya-Long Feng, Ying-Yong Zhao Advances in Clinical Chemistry 66, 101-119, 2014 | 94* | 2014 |