Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus R Shigemoto, A Kinoshita, E Wada, S Nomura, H Ohishi, M Takada, ... Journal of Neuroscience 17 (19), 7503-7522, 1997 | 1304 | 1997 |
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors K Kaupmann, K Huggel, J Heid, PJ Flor, S Bischoff, SJ Mickel, ... Nature 386 (6622), 239-246, 1997 | 1261 | 1997 |
2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist F Gasparini, K Lingenhöhl, N Stoehr, PJ Flor, M Heinrich, I Vranesic, ... Neuropharmacology 38 (10), 1493-1503, 1999 | 856 | 1999 |
Characterization of the Antirrhinum floral homeotic MADS‐box gene deficiens: evidence for DNA binding and autoregulation of its persistent expression throughout flower development. Z Schwarz‐Sommer, I Hue, P Huijser, PJ Flor, R Hansen, F Tetens, ... The EMBO Journal 11 (1), 251-263, 1992 | 529 | 1992 |
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs V Bruno, G Battaglia, A Copani, M D'Onofrio, P Di Iorio, A De Blasi, ... Journal of Cerebral Blood Flow & Metabolism 21 (9), 1013-1033, 2001 | 410 | 2001 |
CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding S Litschig, F Gasparini, D Rueegg, N Stoehr, PJ Flor, I Vranesic, ... Molecular pharmacology 55 (3), 453-461, 1999 | 388 | 1999 |
Antidepressant and anxiolytic‐like effects in mice lacking the group III metabotropic glutamate receptor mGluR7 JF Cryan, PH Kelly, HC Neijt, G Sansig, PJ Flor, H van Der Putten European Journal of Neuroscience 17 (11), 2409-2417, 2003 | 308 | 2003 |
The non-competitive antagonists 2-methyl-6-(phenylethynyl) pyridine and 7-hydroxyiminocyclopropan [b] chromen-1a-carboxylic acid ethyl ester interact with overlapping binding … A Pagano, D Ruegg, S Litschig, N Stoehr, C Stierlin, M Heinrich, ... Journal of Biological Chemistry 275 (43), 33750-33758, 2000 | 298 | 2000 |
A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo K Mitsukawa, R Yamamoto, S Ofner, J Nozulak, O Pescott, S Lukic, ... Proceedings of the National Academy of Sciences 102 (51), 18712-18717, 2005 | 269 | 2005 |
(−)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection M Maj, V Bruno, Z Dragic, R Yamamoto, G Battaglia, W Inderbitzin, ... Neuropharmacology 45 (7), 895-906, 2003 | 240 | 2003 |
SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5 MA Varney, NDP Cosford, C Jachec, SP Rao, A Sacaan, FF Lin, ... Journal of Pharmacology and Experimental Therapeutics 290 (1), 170-181, 1999 | 239 | 1999 |
Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 G Sansig, TJ Bushell, VRJ Clarke, A Rozov, N Burnashev, C Portet, ... Journal of Neuroscience 21 (22), 8734-8745, 2001 | 235 | 2001 |
Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues M Julio-Pieper, PJ Flor, TG Dinan, JF Cryan Pharmacological reviews 63 (1), 35-58, 2011 | 234 | 2011 |
Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function: I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain K Walker, M Bowes, M Panesar, A Davis, C Gentry, A Kesingland, ... Neuropharmacology 40 (1), 1-9, 2001 | 205 | 2001 |
(R, S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo F Gasparini, V Bruno, G Battaglia, S Lukic, T Leonhardt, W Inderbitzin, ... Journal of Pharmacology and Experimental Therapeutics 289 (3), 1678-1687, 1999 | 194 | 1999 |
Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective V Bruno, I Ksiazek, G Battaglia, S Lukic, T Leonhardt, D Sauer, ... Neuropharmacology 39 (12), 2223-2230, 2000 | 154 | 2000 |
Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related … K Mitsukawa, C Mombereau, E Lötscher, DP Uzunov, H van der Putten, ... Neuropsychopharmacology 31 (6), 1112-1122, 2006 | 152 | 2006 |
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice A Palucha, K Klak, P Branski, H Van der Putten, PJ Flor, A Pilc Psychopharmacology 194, 555-562, 2007 | 150 | 2007 |
mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity M Fendt, S Schmid, DR Thakker, LH Jacobson, R Yamamoto, ... Molecular psychiatry 13 (10), 970-979, 2008 | 143 | 2008 |
Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death V Bruno, G Battaglia, I Ksiazek, H Van Der Putten, MV Catania, R Giuffrida, ... Journal of Neuroscience 20 (17), 6413-6420, 2000 | 132 | 2000 |