Pharmacokinetics and clinical pharmacology of monoclonal antibodies in pediatric patients ZH Temrikar, S Suryawanshi, B Meibohm Pediatric Drugs 22, 199-216, 2020 | 51 | 2020 |
Preclinical evaluation of inhalational spectinamide-1599 therapy against tuberculosis M Gonzalez-Juarrero, PB Lukka, S Wagh, A Walz, J Arab, C Pearce, Z Ali, ... ACS infectious diseases 7 (10), 2850-2863, 2021 | 14 | 2021 |
Model-based exposure-response assessment for spectinamide 1810 in a mouse model of tuberculosis S Wagh, C Rathi, PB Lukka, K Parmar, Z Temrikar, J Liu, MS Scherman, ... Antimicrobial agents and chemotherapy 65 (11), 10.1128/aac. 01744-20, 2021 | 12 | 2021 |
Pediatric dose selection for therapeutic proteins PRV Malik, ZH Temrikar, P Chelle, AN Edginton, B Meibohm The Journal of Clinical Pharmacology 61, S193-S206, 2021 | 11 | 2021 |
Screening of methanolic extract of sterculia scaphigera wall seeds for ulcerprotective & antioxidant activity SC Ogale, SB Kasture, VS Kasture, R Tiwari, Z Temrikar World J Pharm Pharm Sci 4, 1332-46, 2014 | 9 | 2014 |
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus GA Phelps, MN Cheramie, DM Fernando, P Selchow, CJ Meyer, ... Proceedings of the National Academy of Sciences 121 (2), e2314101120, 2024 | 3 | 2024 |
Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models X Cao, D Yang, J Parvathareddy, Y Chu, EJ Kim, JN Fitz-Henley, X Li, ... Science Translational Medicine 15 (691), eabl9344, 2023 | 3 | 2023 |
Novel, brain-permeable, cross-species benzothiazole inhibitors of microsomal prostaglandin E synthase-1 (MPGES-1) dampen neuroinflammation in vitro and in vivo MN Sluter, R Bhuniya, X Yuan, A Ramaraju, Y Chen, Y Yu, KR Parmar, ... ACS Pharmacology & Translational Science 6 (4), 587-599, 2023 | 3 | 2023 |
Clinical and translational pharmacology considerations for anti-infectives approved under the FDA animal rule ZH Temrikar, JE Golden, CB Jonsson, B Meibohm Clinical Pharmacokinetics 62 (7), 943-953, 2023 | 2 | 2023 |
Purification of biosynthesized drug metabolites by supercritical fluid chromatography P Liu, Z Temrikar, H Lee, A Gao, N Gonnella, D Xin, ME Taub, ... Drug Metab Pharmacokinet 33 (1), S78, 2018 | 2 | 2018 |
Use of Clinical Trial Simulations to Compare the Performance of Different Approaches for Population Analyses of Pediatric Pharmacokinetic Data Z Temrikar, E Muensterman, B Engelhardt, MEF Mohamed The Journal of Clinical Pharmacology 63 (7), 859-868, 2023 | 1 | 2023 |
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics KR Parmar, PB Lukka, S Wagh, ZH Temrikar, J Liu, RE Lee, M Braunstein, ... Pharmaceutics 15 (6), 1759, 2023 | 1 | 2023 |
Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes ZH Temrikar, S Kodidela, S Kumar, J Liu, GT Robertson, RE Lee, ... Tuberculosis 140, 102342, 2023 | 1 | 2023 |
Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis B Yang, RB Parker, B Meibohm, ZH Temrikar, A Srivastava, SC Laizure Plos one 17 (11), e0278111, 2022 | 1 | 2022 |
PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations and the Identification of Potential Partners for … ZH Temrikar The University of Tennessee Health Science Center, 2023 | | 2023 |
Ethanol Inhibits the Metabolism of the Multiple Sclerosis Drug Dimethyl Fumarate to its Active Metabolite and Decreases Brain Exposure B Yang, RB Parker, B Meibohm, A Srivastava, ZH Temrikar, SC Laizure The FASEB Journal 36, 2022 | | 2022 |
USE OF CLINICAL TRIAL SIMULATIONS TO COMPARE THE PERFORMANCE OF DIFFERENT PHARMACOMETRIC APPROACHES IN ANALYSES OF PEDIATRIC PHARMACOKINETIC DATA. Z Temrikar, E Muensterman, B Engelhardt, M Mohamed CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S34-S34, 2021 | | 2021 |
PK/PD modeling of spectinamide 1599 in Mycobacterium tuberculosis infected mice S Wagh, C Rathi, PB Lukka, K Parmar, Z Temrikar, J Liu, MS Scherman, ... JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S99-S99, 2018 | | 2018 |
New strategies to increase efficacy of vaccines for tetanus-diphtheria-pertussis (TDaP) and other targets ZH Temrikar | | 2017 |