| Structure of the protease domain of memapsin 2 (β-secretase) complexed with inhibitor L Hong, G Koelsch, X Lin, S Wu, S Terzyan, AK Ghosh, XC Zhang, J Tang Science 290 (5489), 150-153, 2000 | 964 | 2000 |
| C2-Symmetric chiral bis (oxazoline)–metal complexes in catalytic asymmetric synthesis AK Ghosh, P Mathivanan, J Cappiello Tetrahedron: Asymmetry 9 (1), 1-45, 1998 | 919 | 1998 |
| Organic carbamates in drug design and medicinal chemistry AK Ghosh, M Brindisi Journal of medicinal chemistry 58 (7), 2895-2940, 2015 | 684 | 2015 |
| A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 496 | 2008 |
| Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human … Y Koh, H Nakata, K Maeda, H Ogata, G Bilcer, T Devasamudram, ... Antimicrobial agents and chemotherapy 47 (10), 3123-3129, 2003 | 465 | 2003 |
| Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS AK Ghosh, HL Osswald, G Prato Journal of medicinal chemistry 59 (11), 5172-5208, 2016 | 440 | 2016 |
| BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease AK Ghosh, HL Osswald Chemical Society Reviews 43 (19), 6765-6813, 2014 | 368 | 2014 |
| Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases MA Clementz, Z Chen, BS Banach, Y Wang, L Sun, K Ratia, ... Journal of virology 84 (9), 4619-4629, 2010 | 356 | 2010 |
| Developing β‐secretase inhibitors for treatment of Alzheimer’s disease AK Ghosh, M Brindisi, J Tang Journal of neurochemistry 120, 71-83, 2012 | 342 | 2012 |
| Design of potent inhibitors for human brain memapsin 2 (β-secretase) AK Ghosh, D Shin, D Downs, G Koelsch, X Lin, J Ermolieff, J Tang Journal of the American Chemical Society 122 (14), 3522-3523, 2000 | 329 | 2000 |
| Structure-based design: potent inhibitors of human brain memapsin 2 (β-secretase) AK Ghosh, G Bilcer, C Harwood, R Kawahama, D Shin, KA Hussain, ... Journal of medicinal chemistry 44 (18), 2865-2868, 2001 | 327 | 2001 |
| The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for … DE Pryor, A O'Brate, G Bilcer, JF Díaz, Y Wang, Y Wang, M Kabaki, ... Biochemistry 41 (29), 9109-9115, 2002 | 312 | 2002 |
| Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance AK Ghosh, BD Chapsal, IT Weber, H Mitsuya Accounts of chemical research 41 (1), 78-86, 2008 | 295 | 2008 |
| Total Synthesis of Ginkgolide A EJ Corey, AK Ghosh Tetrahedron Letters 29, 3205-3206, 1988 | 295 | 1988 |
| Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV AK Ghosh, ZL Dawson, H Mitsuya Bioorganic & medicinal chemistry 15 (24), 7576-7580, 2007 | 285 | 2007 |
| Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid‐19 therapeutics AK Ghosh, M Brindisi, D Shahabi, ME Chapman, AD Mesecar ChemMedChem 15 (11), 907-932, 2020 | 280 | 2020 |
| High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains Y Tie, PI Boross, YF Wang, L Gaddis, AK Hussain, S Leshchenko, ... Journal of molecular biology 338 (2), 341-352, 2004 | 277 | 2004 |
| Crystal structure of memapsin 2 (β-secretase) in complex with an inhibitor OM00-3 L Hong, RT Turner, G Koelsch, D Shin, AK Ghosh, J Tang Biochemistry 41 (36), 10963-10967, 2002 | 275 | 2002 |
| β-Secretase as a therapeutic target for Alzheimer’s disease AK Ghosh, S Gemma, J Tang Neurotherapeutics 5, 399-408, 2008 | 268 | 2008 |
| Subsite specificity of memapsin 2 (β-secretase): implications for inhibitor design RT Turner, G Koelsch, L Hong, P Castenheira, A Ghosh, J Tang Biochemistry 40 (34), 10001-10006, 2001 | 257 | 2001 |
