Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation J Song, O Rechkoblit, TH Bestor, DJ Patel science 331 (6020), 1036-1040, 2011 | 516 | 2011 |
Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro Y Zhang, F Yuan, X Wu, M Wang, O Rechkoblit, JS Taylor, NE Geacintov, ... Nucleic acids research 28 (21), 4138-4146, 2000 | 392 | 2000 |
Error-prone lesion bypass by human DNA polymerase η Y Zhang, F Yuan, X Wu, O Rechkoblit, JS Taylor, NE Geacintov, Z Wang Nucleic acids research 28 (23), 4717-4724, 2000 | 256 | 2000 |
trans-Lesion synthesis past bulky benzo [a] pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases O Rechkoblit, Y Zhang, D Guo, Z Wang, S Amin, J Krzeminsky, N Louneva, ... Journal of Biological Chemistry 277 (34), 30488-30494, 2002 | 228 | 2002 |
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion O Rechkoblit, L Malinina, Y Cheng, V Kuryavyi, S Broyde, NE Geacintov, ... PLoS biology 4 (1), e11, 2006 | 170 | 2006 |
Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion Y Zhang, X Wu, O Rechkoblit, NE Geacintov, JS Taylor, Z Wang Nucleic acids research 30 (7), 1630-1638, 2002 | 161 | 2002 |
Activities of human DNA polymerase κ in response to the major benzo [a] pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion Y Zhang, X Wu, D Guo, O Rechkoblit, Z Wang DNA repair 1 (7), 559-569, 2002 | 129 | 2002 |
Eukaryotic DNA polymerases R Jain, AK Aggarwal, O Rechkoblit Current opinion in structural biology 53, 77-87, 2018 | 114 | 2018 |
Two-step error-prone bypass of the (+)-and (−)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases η and κ Y Zhang, X Wu, D Guo, O Rechkoblit, NE Geacintov, Z Wang Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 510 (1 …, 2002 | 101 | 2002 |
Lesion bypass activities of human DNA polymerase μ Y Zhang, X Wu, D Guo, O Rechkoblit, JS Taylor, NE Geacintov, Z Wang Journal of Biological Chemistry 277 (46), 44582-44587, 2002 | 99 | 2002 |
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy A Ummat, O Rechkoblit, R Jain, J Roy Choudhury, RE Johnson, ... Nature structural & molecular biology 19 (6), 628-632, 2012 | 97 | 2012 |
Structure and mechanism of human PrimPol, a DNA polymerase with primase activity O Rechkoblit, YK Gupta, R Malik, KR Rajashankar, RE Johnson, ... Science advances 2 (10), e1601317, 2016 | 84 | 2016 |
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases S Broyde, L Wang, O Rechkoblit, NE Geacintov, DJ Patel Trends in biochemical sciences 33 (5), 209-219, 2008 | 79 | 2008 |
DNA adduct structure–function relationships: comparing solution with polymerase structures S Broyde, L Wang, L Zhang, O Rechkoblit, NE Geacintov, DJ Patel Chemical research in toxicology 21 (1), 45-52, 2008 | 59 | 2008 |
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4 O Rechkoblit, A Kolbanovskiy, L Malinina, NE Geacintov, S Broyde, ... Nature structural & molecular biology 17 (3), 379-388, 2010 | 56 | 2010 |
Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease K Sato, AA Padgaonkar, SJ Baker, SC Cosenza, O Rechkoblit, ... Nature communications 12 (1), 4671, 2021 | 45 | 2021 |
Primer Length Dependence of Binding of DNA Polymerase I Klenow Fragment to Template− Primer Complexes Containing Site-Specific Bulky Lesions O Rechkoblit, S Amin, NE Geacintov Biochemistry 38 (36), 11834-11843, 1999 | 42 | 1999 |
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases O Rechkoblit, L Malinina, Y Cheng, NE Geacintov, S Broyde, DJ Patel Structure 17 (5), 725-736, 2009 | 36 | 2009 |
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4 … L Zhang, O Rechkoblit, L Wang, DJ Patel, R Shapiro, S Broyde Nucleic acids research 34 (11), 3326-3337, 2006 | 25 | 2006 |
Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase O Rechkoblit, A Kolbanovskiy, H Landes, NE Geacintov, AK Aggarwal Nature communications 8 (1), 965, 2017 | 22 | 2017 |