Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis EW Lee, MS Lee, S Camus, J Ghim, MR Yang, W Oh, NC Ha, DP Lane, ... The EMBO journal 28 (14), 2100-2113, 2009 | 183 | 2009 |
PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis MS Lee, MH Jeong, HW Lee, HJ Han, A Ko, SM Hewitt, JH Kim, KH Chun, ... Nature communications 6 (1), 7769, 2015 | 180 | 2015 |
Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF A Ko, SY Han, CH Choi, H Cho, MS Lee, SY Kim, JS Song, KM Hong, ... Cell Death & Differentiation 25 (6), 1050-1062, 2018 | 76 | 2018 |
Acceleration of gastric tumorigenesis through MKRN1-mediated posttranslational regulation of p14ARF A Ko, JY Shin, J Seo, KD Lee, EW Lee, MS Lee, HW Lee, IJ Choi, ... Journal of the National Cancer Institute 104 (21), 1660-1672, 2012 | 72 | 2012 |
Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation MS Lee, HJ Han, SY Han, IY Kim, S Chae, CS Lee, SE Kim, SG Yoon, ... Nature communications 9 (1), 3404, 2018 | 62 | 2018 |
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer MS Lee, C Dennis, I Naqvi, L Dailey, A Lorzadeh, G Ye, T Zaytouni, ... Nature 616 (7956), 339-347, 2023 | 51 | 2023 |
Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response MS Lee, J Seo, DY Choi, EW Lee, A Ko, NC Ha, J Bok Yoon, HW Lee, ... Cell Death & Differentiation 20 (4), 620-629, 2013 | 49 | 2013 |
Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1 PY Tsai, MS Lee, U Jadhav, I Naqvi, S Madha, A Adler, M Mistry, ... Proceedings of the National Academy of Sciences 118 (10), e2003014118, 2021 | 43 | 2021 |
Molecular chaperone HSP90 is necessary to prevent cellular senescence via lysosomal degradation of p14ARF SY Han, A Ko, H Kitano, CH Choi, MS Lee, J Seo, J Fukuoka, SY Kim, ... Cancer research 77 (2), 343-354, 2017 | 34 | 2017 |
Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis H Xu, MS Lee, PY Tsai, AS Adler, NL Curry, S Challa, E Freinkman, ... Proceedings of the National Academy of Sciences 115 (16), 4228-4233, 2018 | 25 | 2018 |
C-terminus of HSC70-interacting protein (CHIP) inhibits adipocyte differentiation via ubiquitin-and proteasome-mediated degradation of PPARγ JH Kim, S Shin, J Seo, EW Lee, M Jeong, M Lee, HJ Han, J Song Scientific reports 7 (1), 40023, 2017 | 16 | 2017 |
Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis MS Lee, I Naqvi, C Dennis, L Dailey, A Lorzadeh, T Zaytouni, A Adler, ... Cancer Research 81 (22_Supplement), PO-028-PO-028, 2021 | | 2021 |
PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis (vol 6, 7769, 2015) MS Lee, MH Jeong, HW Lee, HJ Han, A Ko, SM Hewitt, JH Kim, KH Chun, ... NATURE COMMUNICATIONS 11 (1), 2020 | | 2020 |
Author Correction: PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis MS Lee, MH Jeong, HW Lee, HJ Han, A Ko, SM Hewitt, JH Kim, KH Chun, ... Nature communications 11, 2020 | | 2020 |
Correction: Molecular chaperone Hsp90 is necessary to prevent cellular senescence VI lysosomal degradation of p14ARF (Cancer Research (2017) 77 (343–354 SY Han, A Ko, H Kitano, CH Choi, MS Lee, J Seo, J Fukuoka, SY Kim, ... Cancer Research 78 (24), 6903, 2018 | | 2018 |