Retinal pigment epithelium replacement therapy for age-related macular degeneration: are we there yet? R Sharma, D Bose, A Maminishkis, K Bharti Annual review of pharmacology and toxicology 60 (1), 553-572, 2020 | 76 | 2020 |
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, ... Nature Communications 12 (1), 7293, 2021 | 42 | 2021 |
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration MJ Song, R Quinn, E Nguyen, C Hampton, R Sharma, TS Park, C Koster, ... Nature methods 20 (1), 149-161, 2023 | 32 | 2023 |
AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration KJ Miyagishima, R Sharma, M Nimmagadda, K Clore-Gronenborn, ... Communications biology 4 (1), 1360, 2021 | 27 | 2021 |
Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells M Farnoodian, D Bose, V Khristov, PJ Susaimanickam, S Maddileti, ... Stem Cell Reports 17 (11), 2438-2450, 2022 | 17 | 2022 |
Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells R Sharma, D Bose, J Montford, D Ortolan, K Bharti STAR protocols 3 (3), 101582, 2022 | 17 | 2022 |
In vitro disease modeling of oculocutaneous albinism type 1 and 2 using human induced pluripotent stem cell-derived retinal pigment epithelium A George, R Sharma, T Pfister, M Abu-Asab, N Hotaling, D Bose, ... Stem Cell Reports 17 (1), 173-186, 2022 | 13 | 2022 |
Retina and RPE lipid profile changes linked with ABCA4 associated Stargardt's maculopathy M Farnoodian, D Bose, F Barone, LM Nelson, M Boyle, B Jun, K Do, ... Pharmacology & Therapeutics 249, 108482, 2023 | 6 | 2023 |
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in atrophic AMD S Ghosh, R Sharma, S Bammidi, V Koontz, M Nemani, M Yazdankhah, ... BioRxiv, 2023.08. 08.552343, 2023 | 3 | 2023 |
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration K Bharti, MJ Song, R Quinn, E Nguyen, TS Park, C Hampton, R Sharma, ... | 3 | 2021 |
Differentiation of monocytes and polarized M1/M2 macrophages from human induced pluripotent stem cells TS Park, R Hirday, R Quinn, SP Jacob, RA Feldman, D Bose, R Sharma, ... STAR protocols 5 (1), 102827, 2024 | 2 | 2024 |
LipidUNet-Machine Learning-Based Method of Characterization and Quantification of Lipid Deposits Using iPSC-Derived Retinal Pigment Epithelium Z Esh, S Suresh, D Ortolan, M Farnoodian, D Bose, J Ryu, A Volkov, ... JoVE (Journal of Visualized Experiments), e65503, 2023 | 2 | 2023 |
Metformin Attenuates the Hallmarks of Stargardt Disease M Farnoodian, F Barone, M Boyle, R Gupta, LM Nelson, DA Bose, B Jun, ... Investigative Ophthalmology & Visual Science 64 (8), 476-476, 2023 | 2 | 2023 |
Modeling the outer blood-retina barrier using microfluidic chips and iPSC-derived RPE and endothelial cells TS Park, E Nguyen, H Pakhchanian, D Ortolan, N Vettikatu, R Dejene, ... Investigative Ophthalmology & Visual Science 62 (8), 2192-2192, 2021 | 2 | 2021 |
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD S Ghosh, R Sharma, S Bammidi, V Koontz, M Nemani, M Yazdankhah, ... Nature communications 15 (1), 6150, 2024 | 1 | 2024 |
Hypoxia of retina pigment epithelium induces type 1 CNV-like morphology within 3D engineered iPSC-RPE/“Choroid” tissues C Hampton, MJ Song, R Dejene, D Bose, R Quinn, K Bharti Investigative Ophthalmology & Visual Science 59 (9), 3272-3272, 2018 | 1 | 2018 |
Deciphering Shared Phenotypic Traits in iPSC-Derived RPE from Ciliopathy Patients with Mutation-Specific Variations D Reichert, D Ortolan, J Montford, J Ryu, CF Lewallen, D Bose, ... Investigative Ophthalmology & Visual Science 65 (7), 3821-3821, 2024 | | 2024 |
Macrophages induce choroidal senescence in an in vitro model of 3D RPE/choroid to cause neovascular AMD-like phenotypes TS Park, R Quinn, C Zhang, E Nguyen, C Cargill, DA Bose, MJ Song, ... Investigative Ophthalmology & Visual Science 65 (7), 4962-4962, 2024 | | 2024 |
Comparison of older and younger fibroblast in the homeostasis of 3D bioprinted oBRB model C Cargill, E Nguyen, A Ali, TS Park, R Hirday, CF Lewallen, M Farnoodian, ... Investigative Ophthalmology & Visual Science 65 (7), 4526-4526, 2024 | | 2024 |
Analysis of Primary Cilia Phenotypes in Patient-Derived iPSC-RPE K Melendez, D Reichert, CF Lewallen, D Ortolan, J Montford, J Ryu, ... Investigative Ophthalmology & Visual Science 65 (7), 4523-4523, 2024 | | 2024 |