Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 2044 | 2019 |
Oncogene-induced senescence as an initial barrier in lymphoma development M Braig, S Lee, C Loddenkemper, C Rudolph, AHFM Peters, ... Nature 436 (7051), 660-665, 2005 | 1472 | 2005 |
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy CA Schmitt, JS Fridman, M Yang, S Lee, E Baranov, RM Hoffman, ... Cell 109 (3), 335-346, 2002 | 1251 | 2002 |
Senescence-associated reprogramming promotes cancer stemness M Milanovic, DNY Fan, D Belenki, JHM Däbritz, Z Zhao, Y Yu, JR Dörr, ... Nature 553 (7686), 96-100, 2018 | 936 | 2018 |
Dissecting p53 tumor suppressor functions in vivo CA Schmitt, JS Fridman, M Yang, E Baranov, RM Hoffman, SW Lowe Cancer cell 1 (3), 289-298, 2002 | 615 | 2002 |
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53 CA Schmitt, ME McCurrach, E de Stanchina, RR Wallace-Brodeur, ... Genes & development 13 (20), 2670-2677, 1999 | 589 | 1999 |
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy JR Dörr, Y Yu, M Milanovic, G Beuster, C Zasada, JHM Däbritz, J Lisec, ... Nature 501 (7467), 421-425, 2013 | 583 | 2013 |
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53 MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ... Cancer cell 22 (1), 51-65, 2012 | 582 | 2012 |
The dynamic nature of senescence in cancer S Lee, CA Schmitt Nature cell biology 21 (1), 94-101, 2019 | 531 | 2019 |
Apoptosis and therapy CA Schmitt, SW Lowe The Journal of pathology 187 (1), 127-137, 1999 | 453 | 1999 |
Senescence, apoptosis and therapy—cutting the lifelines of cancer CA Schmitt Nature Reviews Cancer 3 (4), 286-295, 2003 | 421 | 2003 |
Oncogene-induced senescence: putting the brakes on tumor development M Braig, CA Schmitt Cancer research 66 (6), 2881-2884, 2006 | 367 | 2006 |
Genetic analysis of chemoresistance in primary murine lymphomas CA Schmitt, CT Rosenthal, SW Lowe Nature medicine 6 (9), 1029-1035, 2000 | 342 | 2000 |
Cellular senescence and cancer treatment CA Schmitt Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1775 (1), 5-20, 2007 | 340 | 2007 |
Tumor stroma-derived TGF-β limits myc-driven lymphomagenesis via Suv39h1-dependent senescence M Reimann, S Lee, C Loddenkemper, JR Dörr, V Tabor, P Aichele, ... Cancer cell 17 (3), 262-272, 2010 | 216 | 2010 |
Therapy-induced senescence: opportunities to improve anticancer therapy PG Prasanna, DE Citrin, J Hildesheim, MM Ahmed, S Venkatachalam, ... JNCI: Journal of the National Cancer Institute 113 (10), 1285-1298, 2021 | 207 | 2021 |
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis CM Arends, J Galan-Sousa, K Hoyer, W Chan, M Jäger, K Yoshida, ... Leukemia 32 (9), 1908-1919, 2018 | 176 | 2018 |
Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB N Rohwer, C Dame, A Haugstetter, B Wiedenmann, K Detjen, CA Schmitt, ... PloS one 5 (8), e12038, 2010 | 164 | 2010 |
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf C Bouchard, S Lee, V Paulus-Hock, C Loddenkemper, M Eilers, ... Genes & development 21 (21), 2775-2787, 2007 | 160 | 2007 |
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MR Silvis, N Qutob, ... Cancer cell 33 (2), 322-336. e8, 2018 | 154 | 2018 |