Rapid protein depletion in human cells by auxin-inducible degron tagging with short homology donors T Natsume, T Kiyomitsu, Y Saga, MT Kanemaki Cell reports 15 (1), 210-218, 2016 | 576 | 2016 |
Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment T Natsume, CA Müller, Y Katou, R Retkute, M Gierliński, H Araki, JJ Blow, ... Molecular cell 50 (5), 661-674, 2013 | 165 | 2013 |
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity JD Eaton, L Davidson, DLV Bauer, T Natsume, MT Kanemaki, S West Genes & development 32 (2), 127-139, 2018 | 131 | 2018 |
Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble M Okumura, T Natsume, MT Kanemaki, T Kiyomitsu Elife 7, e36559, 2018 | 126 | 2018 |
Conditional degrons for controlling protein expression at the protein level T Natsume, MT Kanemaki Annual Review of Genetics 51, 83-102, 2017 | 117 | 2017 |
Replication timing maintains the global epigenetic state in human cells KN Klein, PA Zhao, X Lyu, T Sasaki, DA Bartlett, AM Singh, I Tasan, ... Science 372 (6540), 371-378, 2021 | 112 | 2021 |
Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole A Yesbolatova, T Natsume, K Hayashi, MT Kanemaki Methods 164, 73-80, 2019 | 104 | 2019 |
Perichromosomal protein Ki67 supports mitotic chromosome architecture M Takagi, T Natsume, MT Kanemaki, N Imamoto Genes to Cells 21 (10), 1113-1124, 2016 | 61 | 2016 |
Stochastic association of neighboring replicons creates replication factories in budding yeast N Saner, J Karschau, T Natsume, M Gierliński, R Retkute, M Hawkins, ... Journal of Cell Biology 202 (7), 1001-1012, 2013 | 60 | 2013 |
Chk1-mediated Cdc25A degradation as a critical mechanism for normal cell cycle progression H Goto, T Natsume, MT Kanemaki, A Kaito, S Wang, EC Gabazza, ... Journal of cell science 132 (2), jcs223123, 2019 | 55 | 2019 |
Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double‐strand break repair by homologous recombination in both the chicken DT40 … NN Hoa, R Akagawa, T Yamasaki, K Hirota, K Sasa, T Natsume, ... Genes to Cells 20 (12), 1059-1076, 2015 | 53 | 2015 |
Inducible degradation of the human SMC5/6 complex reveals an essential role only during interphase AB Venegas, T Natsume, M Kanemaki, ID Hickson Cell Reports 31 (3), 2020 | 51 | 2020 |
Acute inactivation of the replicative helicase in human cells triggers MCM8–9-dependent DNA synthesis T Natsume, K Nishimura, S Minocherhomji, R Bhowmick, ID Hickson, ... Genes & development 31 (8), 816-829, 2017 | 48 | 2017 |
Ki-67 and condensins support the integrity of mitotic chromosomes through distinct mechanisms M Takagi, T Ono, T Natsume, C Sakamoto, M Nakao, N Saitoh, ... Journal of cell science 131 (6), jcs212092, 2018 | 45 | 2018 |
MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome” SK Das, V Kuzin, DP Cameron, S Sanford, RK Jha, Z Nie, MT Rosello, ... Molecular cell 82 (1), 140-158. e12, 2022 | 41 | 2022 |
Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase α: evidence for a multifunctional role of Mcl1 … Y Tsutsui, T Morishita, T Natsume, K Yamashita, H Iwasaki, F Yamao, ... Current genetics 48, 34-43, 2005 | 37 | 2005 |
Spatial regulation and organization of DNA replication within the nucleus T Natsume, TU Tanaka Chromosome research 18, 7-17, 2010 | 32 | 2010 |
HsSAS-6-dependent cartwheel assembly ensures stabilization of centriole intermediates S Yoshiba, Y Tsuchiya, M Ohta, A Gupta, G Shiratsuchi, Y Nozaki, ... Journal of cell science 132 (12), jcs217521, 2019 | 31 | 2019 |
Inhibiting the MCM8‐9 complex selectively sensitizes cancer cells to cisplatin and olaparib I Morii, Y Iwabuchi, S Mori, M Suekuni, T Natsume, K Yoshida, ... Cancer Science 110 (3), 1044-1053, 2019 | 28 | 2019 |
Three wise centromere functions: see no error, hear no break, speak no delay TU Tanaka, L Clayton, T Natsume EMBO reports 14 (12), 1073-1083, 2013 | 28 | 2013 |