Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility JW Hill, CF Elias, M Fukuda, KW Williams, ED Berglund, WL Holland, ... Cell metabolism 11 (4), 286-297, 2010 | 445 | 2010 |
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner M Perello, I Sakata, S Birnbaum, JC Chuang, S Osborne-Lawrence, ... Biological psychiatry 67 (9), 880-886, 2010 | 429 | 2010 |
Ghrelin mediates stress-induced food-reward behavior in mice JC Chuang, M Perello, I Sakata, S Osborne-Lawrence, JM Savitt, M Lutter, ... The Journal of clinical investigation 121 (7), 2684-2692, 2011 | 383 | 2011 |
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice ED Berglund, CR Vianna, J Donato, MH Kim, JC Chuang, CE Lee, ... The Journal of clinical investigation 122 (3), 1000-1009, 2012 | 371 | 2012 |
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice T Fujikawa, JC Chuang, I Sakata, G Ramadori, R Coppari Proceedings of the National Academy of Sciences 107 (40), 17391-17396, 2010 | 253 | 2010 |
Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin Q Wang, C Liu, A Uchida, JC Chuang, A Walker, T Liu, ... Molecular metabolism 3 (1), 64-72, 2014 | 252 | 2014 |
Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer X Sun, SC Wang, Y Wei, X Luo, Y Jia, L Li, P Gopal, M Zhu, I Nassour, ... Cancer cell 32 (5), 574-589. e6, 2017 | 236 | 2017 |
The nonsteroidal farnesoid X receptor agonist cilofexor (GS‐9674) improves markers of cholestasis and liver injury in patients with primary sclerosing cholangitis M Trauner, A Gulamhusein, B Hameed, S Caldwell, ML Shiffman, ... Hepatology 70 (3), 788-801, 2019 | 215 | 2019 |
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice N Gustavsson, Y Lao, A Maximov, JC Chuang, E Kostromina, JJ Repa, ... Proceedings of the National Academy of Sciences 105 (10), 3992-3997, 2008 | 205 | 2008 |
Combination therapies including cilofexor and firsocostat for bridging fibrosis and cirrhosis attributable to NASH R Loomba, M Noureddin, KV Kowdley, A Kohli, A Sheikh, G Neff, ... Hepatology 73 (2), 625-643, 2021 | 200 | 2021 |
Ghrelin directly stimulates glucagon secretion from pancreatic α-cells JC Chuang, I Sakata, D Kohno, M Perello, S Osborne-Lawrence, JJ Repa, ... Molecular Endocrinology 25 (9), 1600-1611, 2011 | 172 | 2011 |
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ... Molecular psychiatry 20 (4), 500-508, 2015 | 171 | 2015 |
Ghrelin′ s roles in stress, mood, and anxiety regulation JC Chuang, JM Zigman International journal of peptides 2010 (1), 460549, 2010 | 164 | 2010 |
Suppression of the SWI/SNF component Arid1a promotes mammalian regeneration X Sun, JC Chuang, M Kanchwala, L Wu, C Celen, L Li, H Liang, S Zhang, ... Cell stem cell 18 (4), 456-466, 2016 | 151 | 2016 |
Chronic social defeat stress disrupts regulation of lipid synthesis [S] JC Chuang, H Cui, BL Mason, M Mahgoub, AL Bookout, GY Hana, ... Journal of lipid research 51 (6), 1344-1353, 2010 | 150 | 2010 |
A β3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress JC Chuang, V Krishnan, GY Hana, B Mason, H Cui, MB Wilkinson, ... Biological psychiatry 67 (11), 1075-1082, 2010 | 127 | 2010 |
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain M Perello, MM Scott, I Sakata, CE Lee, JC Chuang, S Osborne‐Lawrence, ... Journal of Comparative Neurology 520 (2), 281-294, 2012 | 111 | 2012 |
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment C Celen, JC Chuang, X Luo, N Nijem, AK Walker, F Chen, S Zhang, ... elife 6, e25730, 2017 | 108 | 2017 |
Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells I Sakata, WM Park, AK Walker, PK Piper, JC Chuang, ... American Journal of Physiology-Endocrinology and Metabolism 302 (10), E1300 …, 2012 | 108 | 2012 |
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver Y Xu, ED Berglund, JW Sohn, WL Holland, JC Chuang, M Fukuda, ... Nature neuroscience 13 (12), 1457-1459, 2010 | 100 | 2010 |